Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Supra-papillary Versus Trans-papillary Biliary Stenting in Malignant Peri-hilar Stenosis [NA]
A clinical trial comparing supra-papillary versus trans-papillary biliary stenting in malignant peri-hilar obstruction is not yet recruiting…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors [Phase 1, Phase 2]
APL-5125 is being studied in a Phase 1/2 trial for adults with advanced solid tumors, with recruitment ongoing across several indications in…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Analysis of the Incidence of Cholangiocarcinoma on Choledochal Cyst in a Western Center
A clinical trial update shows a study led by María Teresa Moreno Asencio investigating the incidence of cholangiocarcinoma in patients with …
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Target-specific immunoPET Imaging of Digestive System Carcinoma [NA]
A recruiting clinical trial evaluating a target-specific immunoPET imaging agent for digestive system carcinomas across multiple digestive c…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or Rearrangement [Phase 2]
Phase 2 study evaluating Futibatinib in patients with advanced cholangiocarcinoma harboring FGFR2 fusions; trial status is recruiting.
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Observational Study Protocol: LIVER-R
An observational study protocol called LIVER-R sponsored by AstraZeneca focusing on hepatobiliary cancers, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Clinical Application of PET Imaging Targeting CLDN18.2 in Malignant Tumors
A clinical trial is evaluating PET imaging targeting CLDN18.2 for detecting malignant tumors, with recruitment ongoing in gastric cancer, pa…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Preventing Postoperative Complications in Patients Undergoing High-risk Pancreatoduodenectomy With a Bundle Approach Including Hydrocortisone, Octreotide, and the Teres Ligament Patch (PANENCA) [Phase 4]
Phase 4 clinical trial evaluating a perioperative bundle including hydrocortisone, octreotide, and a teres ligament patch to reduce postoper…
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CLINICAL_TRIALS research · 2025-12-22Clinical Trial Update: Adjuvant Chemotherapy for BTC Based on 3D-PTA [Phase 2]
Phase 2 trial evaluating adjuvant chemotherapy for biliary tract cancer (cholangiocarcinoma) based on 3D-PTA; currently not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: PULSAR Combined With Immunotherapy and Chemotherapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating PULSAR in combination with immunotherapy and chemotherapy for cholangiocarcinoma is currently recruiti…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCA
A clinical trial is evaluating anti-PD-1/PD-L1 antibodies in combination with gemcitabine and cisplatin for advanced cholangiocarcinoma, and…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Phase I/II Study: Allogeneic NK-cell Therapy With Chemotherapy for Post-Surgery PDA or Cholangiocarcinoma Patients [Phase 1, Phase 2]
Phase I/II clinical trial evaluating allogeneic NK-cell therapy with chemotherapy for patients after surgical resection of pancreatic ductal…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Diagnostic Approach for Cholangiocarcinoma Using Liquid Bile Biopsy
This ClinicalTrials.gov study, conducted by University Hospital, Bordeaux, is recruiting to evaluate a liquid bile biopsy-based diagnostic a…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Intravital Microscopy in Human Solid Tumors [NA]
Mayo Clinic is conducting a clinical trial using intravital microscopy in multiple solid tumors, currently recruiting.
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract Cancer [Phase 1]
A Phase 1 clinical trial evaluating chemoimmunotherapy combined with hyperthermia and spatially-fractionated radiotherapy in advanced biliar…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Pembrolizumab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer [Phase 2]
A Phase 2 trial is examining pembrolizumab alone or with lenvatinib or chemotherapy as first-line treatment for advanced biliary tract cance…
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: Trop2-targeted immunoPET Imaging of Solid Tumors [Phase 2, Phase 3]
Clinical trial update for Trop2-targeted immunoPET imaging of solid tumors, currently in Phase 2/3 and recruiting.
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer [Phase 1]
Phase 1 trial evaluating the combination of guadecitabine and durvalumab in advanced cholangiocarcinoma, gallbladder cancer, hepatocellular …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver Injury [NA]
A mechanistic clinical trial evaluating the protective and regenerative effects of Spirulina on hepatectomy-related liver injury in cholangi…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Perioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers [Phase 2]
Phase 2 perioperative regimen of gemcitabine, cisplatin, and pembrolizumab for potentially resectable biliary tract cancers; sponsored by Jo…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer
This clinical trial update describes a noninvasive miRNA-based test being explored for screening gastrointestinal cancers. It is currently r…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational Study
An observational study evaluating the use of ivosidenib for locally advanced or metastatic cholangiocarcinoma with IDH1 R132 mutation after …
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: A Study of GV20-0251 in Advanced or Refractory Solid Tumors [Phase 1]
This Phase 1 clinical trial update indicates that GV20-0251 is being studied in advanced or refractory solid tumors and is currently recruit…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating a recombinant EphB4-HSA fusion protein in combination with standard chemotherapy for advanced or metastatic solid t…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle Hepato-Pancreato-Biliary Cancers
This clinical trial protocol from the University of Nottingham aims to characterize biliary strictures and hepatobiliary–pancreatic focal le…