Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/Phase 2 study of AK130 in combination with AK112 for advanced biliary tract cancer, currently rec…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma [Phase 2]
A Phase 2 clinical trial evaluating sacituzumab govitecan for locally advanced, recurrent, or metastatic cholangiocarcinoma is currently act…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Pilot Comparing ctDNA IDV vs. SPV Sample in Pts Undergoing Biopsies for Hepatobiliary and Pancreatic Cancers [NA]
A pilot study comparing two ctDNA sampling methods (ctDNA IDV vs SPV) in patients undergoing biopsies for hepatobiliary and pancreatic cance…
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CLINICAL_TRIALS research · 2026-02-20Clinical Trial Update: Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes [NA]
Cedars-Sinai Medical Center is recruiting for a study evaluating virtual reality to manage gastrointestinal cancer pain and improve patient-…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations [Phase 2]
This Clinical Trial Update reports on a Phase 2 study of olaparib in patients with advanced glioma, cholangiocarcinoma, or other IDH1/IDH2-m…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial evaluating the combination of trifluridine/tipiracil with oxaliplatin for advanced or metastatic biliary tract cancer…
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CLINICAL_TRIALS research · 2026-02-19Clinical Trial Update: An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic Cholangiocarcinoma [Phase 3]
An early access (compassionate use) study of ivosidenib for patients with pretreated cholangiocarcinoma (locally advanced or metastatic) is …
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Biobank for Cholestatic Liver Diseases.
Mayo Clinic is recruiting for a biobank study of cholestatic liver diseases, including primary sclerosing cholangitis and primary biliary ch…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC Patients
A Mayo Clinic-sponsored study aims to characterize biliary cell-derived organoids from bile samples of patients with primary sclerosing chol…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study [Phase 2]
A Phase 2 trial (The Knight SHIFT Study) is comparing morning versus afternoon administration of immunotherapy for advanced or metastatic so…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or Mesothelioma [Phase 1]
Phase 1 trial update for SynKIR-110 in mesothelin-expressing ovarian cancer, cholangiocarcinoma, and mesothelioma, currently recruiting.
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CLINICAL_TRIALS research · 2026-02-05Clinical Trial Update: Prospective Exploratory Study of FAPi PET/CT With Histopathology Validation in Patients With Various Cancers [Phase 1]
Phase 1 exploratory study evaluating FAPi PET/CT imaging with histopathology validation in patients with various cancers. The trial collects…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Evaluation of the Safety, Tolerability and Efficacy of iNeo-Vac-R01, an Individualized mRNA Therapeutic Technology Based on Tumor Neoantigens, for Adjuvant Treatment in Patients With Biliary Malignant Tumors After Radical Resection [Phase 1, Phase 2]
This clinical trial update reports ongoing Phase 1/2 evaluation of iNeo-Vac-R01, an individualized mRNA neoantigen vaccine, as adjuvant ther…
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CLINICAL_TRIALS research · 2026-01-27Clinical Trial Update: BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating BOLD-100 in combination with FOLFOX for advanced solid tumors, including colorectal cancer, pancreatic…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Study of Gemcitabine, Cisplatin, AB680 and AB122 During First Line Treatment of Advanced Biliary Tract Cancers (QUIC) [Phase 2]
Phase 2 clinical trial assessing a four-drug combination (gemcitabine, cisplatin, AB680, AB122) as first-line therapy for advanced biliary t…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a combination of GNS561 and trametinib in advanced KRAS-mutated cholangiocarcinoma is currently recrui…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: Laryngopharyngeal Injury After Endotracheal Intubation Under General Anesthesia
A Zhejiang University-sponsored clinical trial (NCT07359586) is currently recruiting to evaluate laryngopharyngeal injury after endotracheal…
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CLINICAL_TRIALS research · 2026-01-22Clinical Trial Update: A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating MK-2870 alone or with other therapies for gastrointestinal cancers is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Lenvatinib Plus Paclitaxel for Patients With Advanced Biliary Tract Cancer Who Failed to Gemcitabine-based Treatment [Phase 2]
Phase 2 clinical trial evaluating lenvatinib plus paclitaxel in patients with advanced biliary tract cancer after gemcitabine-based therapy;…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract
This clinical trial update describes the collection of tissue and blood from patients with benign and malignant tumors of the soft tissue an…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Pemigatinib + Afatinib in Advanced Refractory Solid Tumors [Phase 1]
A Phase 1 clinical trial evaluating the combination of pemigatinib and afatinib in advanced, unresectable, or metastatic solid tumors is cur…
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: Hepatobiliary and Pancreatic Tumor Biobank
Clinical trial update describing a hepatobiliary and pancreatic tumor biobank study led by Zhejiang University, currently not recruiting.
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating pemigatinib plus atezolizumab and bevacizumab for advanced cholangiocarcinoma with FGFR2 fusion, current…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Exploration of Sintilimab + Bevacizumab + AG Chemotherapy as First-Line Treatment for Unresectable Advanced/Metastatic Cholangiocarcinoma [Phase 2]
This is a Phase 2 clinical trial exploring a combination of sintilimab, bevacizumab, and AG chemotherapy as first-line treatment for unresec…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation [Phase 1, Phase 2]
This clinical trial evaluates the combination of ivosidenib, durvalumab, and gemcitabine/cisplatin as first-line therapy for locally advance…