Brain Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors [Phase 1]
Pfizer is conducting a Phase 1 study of PF-07799544 as a monotherapy or in combination for advanced solid tumors, including melanoma and gli…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: MRI and Blood Biomarkers for the Prediction of Neurocognitive Decline Following Brain Radiation
A terminated clinical trial evaluating MRI and blood biomarkers for predicting neurocognitive decline after brain radiation in patients with…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Two Cut-Off Values of Plethysmographic Variability Index to Guide Intraoperative Fluid Therapy on Serum Lactate in Patients Undergoing Excision of Supra-Tentorial Brain Tumors [NA]
A completed Cairo University trial investigated two cut-off values of plethysmographic variability index to guide intraoperative fluid thera…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Radiologic Pathologic Correlation of Advanced MR Imaging to Guide the Biopsy of Cerebral Malignancies [NA]
MD Anderson is recruiting a study to evaluate radiologic-pathologic correlations using advanced MRI techniques to guide biopsies of brain tu…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Evaluation of Gadolinium Based Contrast Agents for Portable MR Imaging Systems [NA]
This clinical trial update indicates enrollment by invitation to evaluate gadolinium-based contrast agents for Hyperfine's portable MRI syst…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy
Completed study profiling metabolites and epigenetic marks in body fluids from adults with brain tumors or lung cancer undergoing radiation …
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Brain Irradiation for Childhood Cancer - Endocrine Monitoring During the First Years [NA]
This clinical trial update covers a pediatric brain irradiation study in childhood cancer that includes endocrine monitoring during the earl…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Arterial Pressure and Surgical Hemostasis in Elective Neurosurgery.
A completed clinical trial evaluating how arterial pressure impacts surgical hemostasis in elective neurosurgery.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Phase I, Single-arm, Open-label Clinical Study to Evaluate the Safety, Pharmacokinetics, and Preliminary Efficacy of CHT101 Cell Infusion in Adult Subjects With Recurrent or Progressive Malignant Primary Brain Tumors（CROWN） [Phase 1]
Phase I, single-arm, open-label study to evaluate safety, pharmacokinetics, and preliminary efficacy of CHT101 cell infusion in adults with …
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Effect of Dexmedetomidine on Brain Homeostasis and Neurocognitive Outcome [Phase 4]
Phase 4 trial assessing the effect of dexmedetomidine on brain homeostasis and neurocognitive outcomes in patients with brain tumors and rel…
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CLINICAL_TRIALS research · 2026-03-25Clinical Trial Update: Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures [EARLY_Phase 1]
This document describes a NOT_YET_RECRUITING Phase 1 pilot study evaluating Panitumumab-IRDye800 as an optical imaging agent to detect intra…
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CLINICAL_TRIALS research · 2026-03-20Clinical Trial Update: Guided Meditation During Radiation Therapy for Brain Tumors [NA]
A recruiting clinical trial is evaluating guided meditation during radiation therapy for brain neoplasms.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: The Effects of Intraoperative Tranexamic Acid on Perioperative Bleeding In Craniotomies [Phase 3]
Phase 3 trial evaluating intraoperative tranexamic acid to reduce perioperative bleeding during craniotomies in patients with brain tumors i…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation [NA]
This clinical trial investigates proton craniospinal irradiation with bone-sparing techniques to reduce radiation-related growth decrement i…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors [Phase 2]
An ongoing Phase 2 clinical trial evaluating 18F-DOPA PET/CT to improve clinical management of brain tumors; the study is not yet recruiting…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Neuromodulation-Induced Cortical Prehabilitation in High Grade Glioma Near the Motor Pathway: Cortical Plasticity Assessed by Navigated Transcranial Magnetic Stimulation (nTMS) [NA]
A clinical trial evaluating neuromodulation to prehabilitate cortical function in patients with high-grade glioma near motor pathways, using…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Real Time Craniotomy Planning Using Mixed Reality
A clinical trial sponsored by Brainlab AG is testing real-time craniotomy planning using mixed reality, with recruitment not yet started.
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Dasatinib, Temsirolimus, and Cyclophosphamide in Treating Patients With Advanced, Recurrent, or Refractory Solid Tumors [Phase 1]
A Phase 1 trial evaluating the combination of dasatinib, temsirolimus, and cyclophosphamide for advanced malignant solid tumors and recurren…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Single Versus Multifraction Salvage Spine Stereotactic Radiosurgery for Previously Irradiated Spinal Metastases [Phase 2]
A Phase 2 clinical trial is evaluating single-fraction versus multifraction salvage spine stereotactic radiosurgery for previously irradiate…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors [NA]
The document summarizes a Mayo Clinic clinical trial exploring placing an Ommaya reservoir at brain tumor biopsy to enable longitudinal biom…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Perioperative Multimodal Analgesia for Supratentorial Craniotomy [NA]
Clinical trial update for perioperative multimodal analgesia in supratentorial craniotomy; the study is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-27Clinical Trial Update: Fluorescence-Guided Imaging of Brain Tumors: A Safety Study Using SBK2-ICG [Phase 1]
Phase 1 safety study evaluating SBK2-ICG for fluorescence-guided imaging of malignant brain tumors, including glioma. The trial is currently…
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CLINICAL_TRIALS trial_result · 2026-02-23Clinical Trial Update: Comparison of Systemic Opioid (Morphine) and Pre-Incision Bilateral Scalp Nerve Block for Pain Management in Craniotomy Patients [Phase 4]
A Phase 4 trial comparing systemic morphine to a pre-incision bilateral scalp nerve block for pain management in craniotomy patients with su…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients [NA]
A clinical trial update for OT SMILE, a group occupational therapy intervention for patients with primary brain tumors, including glioblasto…
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: C-SMART: Cognitive Strategies, Mindfulness, and Rehabilitation Therapy for Patients With Primary Brain Tumors
This ClinicalTrials.gov update indicates the C-SMART trial, which assesses cognitive strategies, mindfulness, and rehabilitation therapy for…