Brain Neoplasms

CLINICAL_TRIALS research · 2026-02-20

Clinical Trial Update: [18F]FET PET for Characterization of Progressive or Recurrent Glioma From Treatment Related Changes

Clinical trial update for a retrospective study using the radiotracer [18F]FET PET to characterize progressive or recurrent glioma after tre…

CLINICAL_TRIALS research · 2026-02-19

Clinical Trial Update: SIMPLIFication of Care Pathways for Patients With Rare Brain Tumors Through Artificial Intelligence [NA]

A clinical trial titled SIMPLIFication of Care Pathways for Patients With Rare Brain Tumors Through Artificial Intelligence is currently rec…

CLINICAL_TRIALS research · 2026-02-13

Clinical Trial Update: An Exercise Intervention for Improving Mental and Physical Health in Patients With Primary Brain Tumors and Their Caregivers, ET-NEURO Trial [NA]

The ET-NEURO trial is investigating an exercise intervention to improve mental and physical health in patients with primary brain tumors and…

CLINICAL_TRIALS trial_result · 2026-02-12

Clinical Trial Update: Relationship of PNI and Clinical Outcome in Patients Undergoing Brain Tumor Surgery

A completed clinical trial evaluating whether the Prognostic Nutritional Index (PNI) predicts clinical outcomes in patients undergoing brain…

CLINICAL_TRIALS research · 2026-02-11

Clinical Trial Update: FASt Track in Elective Neurosurgery: the Role of Low Propofol Bis-NOL Guided General Anaesthesia for Full, Early and Safe Awakening

A clinical trial update describes a study evaluating low-propofol Bis-NOL guided general anesthesia for elective supratentorial brain tumor …

CLINICAL_TRIALS research · 2026-02-09

Clinical Trial Update: MR Elastography in Intracranial Lesions: Feasibility & Accuracy

A clinical trial update evaluating the feasibility and accuracy of magnetic resonance elastography for intracranial lesions. The study is cu…

CLINICAL_TRIALS research · 2026-02-09

Clinical Trial Update: DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) [NA]

A clinical trial evaluating dexmedetomidine for postoperative analgesia and delirium prevention after neurosurgery, currently not recruiting…

CLINICAL_TRIALS research · 2026-01-30

Clinical Trial Update: Detection of Brain Metastases Using a Novel Gadolinium-Weighted MRI Sequence: A Prospective Comparison

A prospective clinical trial from Region Stockholm evaluating a novel gadolinium-weighted MRI sequence for detecting brain metastases; the s…

CLINICAL_TRIALS research · 2026-01-09

Clinical Trial Update: Virtual Home-based Exercise Intervention (RISE) to Improve Cancer-Related Cognitive Impairment and Gut Microbiome in Adolescent and Young Adult Brain Tumor Survivors [NA]

This clinical trial update describes a home-based exercise program (RISE) intended to improve cancer-related cognitive impairment and gut mi…

CLINICAL_TRIALS research · 2026-01-07

Clinical Trial Update: Radiation Therapy in Treating Patients With Recurrent Brain Tumors Who Have Undergone Previous Radiation Therapy [NA]

Clinical trial update shows a study on radiation therapy for patients with recurrent brain tumors who previously received radiation; the stu…

CLINICAL_TRIALS research · 2026-01-05

Clinical Trial Update: Platelets Activation in Brain Neoplasms [NA]

A clinical trial investigating platelets activation in brain neoplasms, including glioma, is currently recruiting. The sponsor is Fondation …

CLINICAL_TRIALS research · 2025-12-31

Clinical Trial Update: PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study [NA]

This clinical trial update describes a microdosing PET imaging study using a 124I-labeled cRGDY silica nanomolecular particle tracer in pati…

CLINICAL_TRIALS research · 2025-12-30

Clinical Trial Update: Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases [NA]

A Mayo Clinic-led clinical trial investigates breathing practices to support brain and mental health in cancer and neurodegenerative disease…

CLINICAL_TRIALS trial_result · 2025-12-26

Clinical Trial Update: Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent [Phase 2]

Phase 2 ascending-dose study of RVP-001, a manganese-based MRI contrast agent, completed to assess safety and preliminary efficacy in CNS le…

CLINICAL_TRIALS research · 2025-12-17

Clinical Trial Update: NeuroPathways Intervention for Brain Tumor Patients [NA]

A clinical trial sponsored by Massachusetts General Hospital investigating NeuroPathways Intervention for glioma/brain tumors is currently r…

CLINICAL_TRIALS trial_result · 2025-12-16

Clinical Trial Update: A Comparative Study Between Opioids Free Anesthesia and Opioid Anesthesia in Patients With Supratentorial Tumor Resection [NA]

A completed clinical trial comparing opioid-free anesthesia to opioid anesthesia in patients undergoing supratentorial tumor resection.

CLINICAL_TRIALS research · 2025-11-24

Clinical Trial Update: DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers. [Phase 2, Phase 3]

This clinical trial update describes Arm 03 of the DETERMINE trial evaluating entrectinib in adults, pediatric, and teenage/young adult pati…

CLINICAL_TRIALS research · 2025-11-21

Clinical Trial Update: HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer) [NA]

The HOBSCOTCH-CA trial, a home-based self-management and cognitive training program for brain cancer patients, is currently recruiting.

CLINICAL_TRIALS research · 2025-11-20

Clinical Trial Update: Levetiracetam for Seizure Prevention After Brain Tumor Surgery [Phase 3]

Phase 3 trial of levetiracetam to prevent postoperative seizures after brain tumor surgery is listed, but recruitment has not yet begun.

CLINICAL_TRIALS research · 2025-11-18

Clinical Trial Update: A Study of the Boron Neutron Capture Therapy (BNCT) Using B10 L-BPA in Malignant Brain Tumors [Phase 1, Phase 2]

A Phase 1/2 clinical trial evaluating boron neutron capture therapy using boron-10 labeled L-BPA for malignant brain tumors. The study is sp…

CLINICAL_TRIALS research · 2025-11-18

Clinical Trial Update: Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors [NA]

An MD Anderson Cancer Center trial is recruiting to evaluate electrocorticography for mapping functional brain areas during brain tumor surg…

CLINICAL_TRIALS research · 2025-11-12

Clinical Trial Update: Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery [NA]

This update indicates ongoing recruitment for a study evaluating intraoperative fluorescence-guided monitoring using 5-ALA during brain tumo…

CLINICAL_TRIALS trial_result · 2025-10-23

Clinical Trial Update: A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement [Phase 1]

A first-in-human Phase 1 trial of PF-07284890 in patients with BRAF V600 mutant solid tumors, including those with brain involvement, has be…

CLINICAL_TRIALS trial_result · 2025-10-10

Clinical Trial Update: Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. [EARLY_Phase 1]

An early-phase study evaluating the Ga-68 labeled FF58 radiotracer in selected solid tumors overexpressing integrins has been terminated.

CLINICAL_TRIALS research · 2025-10-07

Clinical Trial Update: Integrated PET/MR Imaging With Amino Acid Radiotracers in the Evaluation of Brain Neoplasms: Assessing Diagnostic Accuracy and Therapeutic Response

This clinical trial evaluates integrated PET/MR imaging using amino acid radiotracers to assess diagnostic accuracy and therapeutic response…

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