Bipolar Disorder
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental Disorders
A prospective observational study examining how sociodemographic factors, blood-based biomarkers, and psychiatric symptoms relate across sev…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Evaluation of the Genetics of Bipolar Disorder
The NIMH-sponsored study on the genetics of bipolar disorder is active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: mHealth Estimate-based Algorithms Signaling Upcoming Recurrence of Episodes in Bipolar Disorders
A clinical trial is recruiting to evaluate mHealth estimate-based algorithms that signal upcoming recurrence of episodes in bipolar disorder…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine [Phase 3]
Phase 3 trial evaluating adjunctive KarXT (xanomeline/trospium) for mania in adults with Bipolar I Disorder on lithium, valproate, or lamotr…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents [NA]
A clinical trial update indicates the Child Bipolar Network is recruiting adolescents to evaluate a ketogenic diet approach for bipolar diso…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Socio-cognitive and Biological Responses to Maltreatment
A clinical trial update from Medical University Innsbruck on socio-cognitive and biological responses to maltreatment in Bipolar I disorder …
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT [NA]
Clinical trial comparing venous versus arterial tourniquet use for seizure monitoring during electroconvulsive therapy; the study targets ad…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study to Investigate Lithium Brain/Plasma Pharmacokinetics and Safety of an AL001 Oral Capsule Compared to a Marketed Immediate-release Lithium Carbonate Capsule in Subjects With Bipolar I Disorder [Phase 1, Phase 2]
Phase 1/2 clinical trial comparing AL001 oral capsules to marketed lithium carbonate capsules to study brain/plasma pharmacokinetics and saf…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital [NA]
This clinical trial update describes a study at The Royal Ottawa Mental Health Centre testing action-based cognitive remediation for transdi…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Natural History of Depression, Bipolar Disorder and Suicide Risk
This document describes an ongoing NIMH-sponsored clinical research study characterizing the natural history of depression, bipolar disorder…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE. [Phase 2]
A Phase 2 multicenter clinical trial evaluating LB-102 for Bipolar I Disorder is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Decoding Emotional Dynamics in Bipolar Disorder [NA]
A registered clinical trial evaluating emotional dynamics in individuals with Bipolar I or II disorder compared with healthy controls; curre…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1) [Phase 2]
A Phase 2 clinical trial evaluating Brenipatide for Bipolar Disorder is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder [NA]
This clinical trial update describes an ongoing study at Massachusetts General Hospital evaluating a future-thinking behavioral intervention…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder [NA]
A clinical trial is investigating ketosis as a way to modulate metabolic pathways in bipolar disorder, and it is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Enhancing Veteran-Clinical Collaboration in VA PRRCs [NA]
A VA-sponsored initiative aims to enhance veteran-clinical collaboration within VA PRRCs; the study is currently not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder [Phase 3]
Phase 3 clinical trial evaluating KarXT for manic episodes in Bipolar I disorder is recruiting. The study is sponsored by Bristol-Myers Squi…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder [Phase 2]
This is a Phase 2 clinical trial evaluating adverse events and changes in disease activity of oral Icalcaprant in adults with bipolar I or I…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder [Phase 1]
A Phase 1 clinical trial evaluating BXCL501 for efficacy and safety in agitation associated with pediatric schizophrenia and related disorde…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers
NIMH-sponsored clinical trial evaluating mood and anxiety disorders, including bipolar disorder and major depressive disorder, is currently …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder [Phase 2]
This clinical trial update describes a Phase 2 study evaluating the adverse events of oral ABBV-932 in adults with depressive episodes assoc…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2) [Phase 3]
This clinical trial update describes a Phase 3 study (BALSAM-2) evaluating the efficacy and safety of KarXT for manic episodes in Bipolar I …
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: An Open-label Study of Azetukalner in Bipolar I or II Depression (X-CEED-OLE) [Phase 3]
Open-label Phase 3 trial evaluating azetukalner for bipolar depression in bipolar I or II disorder. Enrollment is ongoing by invitation.
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Transcranial Photobiomodulation for Bipolar Depression [NA]
This clinical trial update indicates that a study on transcranial photobiomodulation for bipolar depression (sponsored by Vielight Inc.) is …
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder [Phase 2]
RAP-219 is being studied in a Phase 2 trial to assess its efficacy and safety in adults with Bipolar I Disorder, and the study is currently …