Bipolar Depression
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Minocycline for Bipolar Depression [Phase 4]
Phase 4 clinical trial evaluating minocycline for bipolar depression has completed; results were posted in January 2017.
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CLINICAL_TRIALS trial_result · 2016-11-22Clinical Trial Update: Treatment of Bipolar Depression With H1-Coil Deep Brain rTMS: Clinical-Cognitive and Safety Evaluation [NA]
This trial update reports on the safety and clinical-cognitive evaluation of H1-Coil deep brain rTMS for bipolar depression. The study statu…
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CLINICAL_TRIALS trial_result · 2016-10-19Clinical Trial Update: Ceftriaxone in the Management of Bipolar Depression [NA]
Clinical trial update for ceftriaxone in bipolar depression; study terminated with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-03Clinical Trial Update: Evaluate the Efficacy and Safety of Quetiapine Fumarate (SEROQUEL) Extended Release as Monotherapy in the Treatment of Patients With Bipolar Depression [Phase 3]
Phase 3 trial evaluating quetiapine fumarate extended-release as monotherapy for bipolar depression has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2016-01-12Clinical Trial Update: Bipolar Depression Before and After Lamotrigine Treatment [Phase 3]
Phase 3 clinical trial evaluating lamotrigine for bipolar depression has completed and posted results.
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CLINICAL_TRIALS trial_result · 2015-12-16Clinical Trial Update: Treatment Resistant Bipolar Depression [Phase 1]
Phase 1 trial update for treatment-resistant bipolar depression has been terminated, with no results reported.
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CLINICAL_TRIALS trial_result · 2015-11-02Clinical Trial Update: Memantine Augmentation of Lamotrigine Incomplete-Response in Bipolar Depression [Phase 4]
Phase 4 study results evaluating memantine added to lamotrigine for bipolar depression with incomplete response were posted.
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CLINICAL_TRIALS trial_result · 2015-11-02Clinical Trial Update: Levetiracetam in the Management of Bipolar Depression [NA]
Clinical trial update for levetiracetam in bipolar depression; study completed with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-09-02Clinical Trial Update: Efficacy Study of Lisdexamfetamine to Treat Bipolar Depression [Phase 3]
A Phase 3 efficacy study evaluating lisdexamfetamine for bipolar depression has been terminated; no efficacy results are provided in this up…
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CLINICAL_TRIALS trial_result · 2015-05-28Clinical Trial Update: Repetitive Transcranial Magnetic Stimulation for Treating Resistant Bipolar Depression [Phase 2, Phase 3]
Phase 2/Phase 3 trial update on repetitive transcranial magnetic stimulation for resistant bipolar depression. The study status is completed…
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CLINICAL_TRIALS withdrawal · 2014-07-08Clinical Trial Update: What is the Antidepressant Mechanism of Action of Quetiapine in Bipolar Depression? [Phase 3]
A Phase 3 trial evaluating the antidepressant mechanism of action of quetiapine in bipolar depression was withdrawn, with no trial results r…
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CLINICAL_TRIALS withdrawal · 2014-01-22Clinical Trial Update: RU-486 in the Treatment of Bipolar Depression [Phase 2]
A Phase 2 trial of RU-486 (mifepristone) for bipolar depression has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-11-21Clinical Trial Update: Neurophysiologic Changes in Patients With Bipolar Depression [Phase 4]
Phase 4 clinical trial evaluating neurophysiologic changes in patients with bipolar depression; the current status of the study is unknown.
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CLINICAL_TRIALS trial_result · 2013-08-09Clinical Trial Update: Longitudinal Study on the Neuroprotective and Neurotrophic Effects of Lithium [Phase 4]
A Phase 4 longitudinal study evaluating the neuroprotective and neurotrophic effects of lithium in bipolar disorder and bipolar depression h…
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CLINICAL_TRIALS trial_result · 2013-02-04Clinical Trial Update: Bipolar Study of Seroquel XR With Pramipexole Dihydrochloride [Phase 2]
A Phase 2 trial evaluating quetiapine XR in combination with pramipexole dihydrochloride for bipolar depression has completed.
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CLINICAL_TRIALS trial_result · 2013-01-30Clinical Trial Update: Magnetic Resonance Imaging Study of Lisdexamfetamine for Bipolar Depression [Phase 4]
Phase 4 clinical trial evaluating lisdexamfetamine for bipolar depression was terminated; results were posted in 2013.
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CLINICAL_TRIALS withdrawal · 2012-11-29Clinical Trial Update: Effects of Electroconvulsive Therapy (ECT) in Bipolar Depression
The McLean Hospital-sponsored trial evaluating electroconvulsive therapy for bipolar depression has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-up
The update provides functional outcome data from AstraZeneca's trial in patients with acute bipolar depression after 8 months of follow-up.
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CLINICAL_TRIALS trial_result · 2012-07-18Clinical Trial Update: The Use of a Mitochondrial Enhancement Treatment in Bipolar Disorder [Phase 2]
Phase 2 clinical trial evaluating a mitochondrial enhancement treatment for bipolar depression has completed, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-04-10Clinical Trial Update: Quetiapine XR Versus Sertraline in Acute Bipolar Depression as add-on Therapy [Phase 3]
Phase 3 head-to-head trial comparing quetiapine XR added to antidepressant therapy versus sertraline in adults with acute bipolar depression…
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FDA approval · 2012-03-27FDA Approved: QUETIAPINE FUMARATE — Original Application (Sun Pharmaceutical Industries, Inc.)
FDA approved the original application for a generic version of quetiapine fumarate from Sun Pharmaceutical Industries.
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Double Blind Randomized Controlled, H1 Coil In Subjects With Bipolar Depression [NA]
Clinical trial update of a double-blind randomized controlled trial using the H1 Coil in bipolar depression; the current status is unknown.
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CLINICAL_TRIALS trial_result · 2011-10-25Clinical Trial Update: Lamotrigine for Symptoms of Geriatric Bipolar Depression [Phase 3]
This Phase 3 clinical trial evaluating lamotrigine for symptoms of geriatric bipolar depression has completed and posted results. The study …
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CLINICAL_TRIALS trial_result · 2011-09-28Clinical Trial Update: Functional Connectivity in Mood Regulating Circuit In Bipolar Depression and Mania [Phase 4]
Phase 4 study assessing functional connectivity in mood-regulating circuits for bipolar depression has completed.
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CLINICAL_TRIALS trial_result · 2011-03-31Clinical Trial Update: Study Comparing the Tolerability of Seroquel IR With Seroquel XR in Patients With Bipolar Depression [Phase 4]
A Phase 4 study comparing tolerability of Seroquel immediate-release versus Seroquel extended-release in patients with bipolar depression ha…