Bipolar Depression
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-13Clinical Trial Results: A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression [Phase 2]
Phase 2 trial results for a fatty acid amide hydrolase inhibitor (palmitoylethanolamide) in Bipolar Depression have been completed and resul…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study [Phase 2, Phase 3]
A non-inferiority study evaluating electro-magnetic convulsive therapies for major depressive disorder and bipolar depression is ongoing in …
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CLINICAL_TRIALS withdrawal · 2026-04-14Clinical Trial Update: Dopamine D3 Receptor Occupancy in Bipolar Depression [Phase 4]
A Phase 4 clinical trial evaluating dopamine D3 receptor occupancy in bipolar depression has been withdrawn.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Probiotics to Prevent Relapse After Hospitalization for Bipolar Depression [Phase 2]
Phase 2 clinical trial evaluating whether probiotics can prevent relapse after hospitalization for bipolar depression; the study NCT03349528…
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CLINICAL_TRIALS trial_result · 2026-04-06Clinical Trial Update: Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder [Phase 2]
Phase 2 trial evaluating low-dose interleukin-2 therapy in Bipolar Depression has completed.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression) [Phase 3]
A Phase 3 randomized trial is evaluating Azetukalner versus placebo for depressive episodes in bipolar disorder (bipolar I or II); the study…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression [NA]
An update on a clinical trial evaluating low-field magnetic stimulation imaging biomarkers in geriatric bipolar disorder. The study is curre…
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CLINICAL_TRIALS research · 2026-03-18Clinical Trial Update: Low Frequency Right Dorsolateral Pre Frontal Cortical Repetitive TMS for Bipolar Depression [Phase 3]
A Phase 3 trial is evaluating low-frequency right dorsolateral prefrontal cortex repetitive transcranial magnetic stimulation for bipolar de…
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CLINICAL_TRIALS research · 2026-03-16Clinical Trial Update: Empagliflozin Adjunctive Therapy in Bipolar Depression [NA]
Clinical trial update on empagliflozin as adjunctive therapy for bipolar depression, sponsored by the University of Sao Paulo; the study is …
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Ketamine for Treatment-Resistant Bipolar Disorder [Phase 2]
A Phase 2 clinical trial evaluating ketamine for treatment-resistant bipolar disorder has completed.
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: Maintenance Ketamine Infusions for Treatment-Resistant Bipolar Depression [Phase 2]
A Phase 2 completed trial update evaluating maintenance ketamine infusions for treatment-resistant bipolar depression.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: PROgram To Enhance Cardiovascular Risk Trough an Intervention of Nutrition in Bipolar Disorder [NA]
It describes an ongoing University of Sao Paulo-sponsored clinical trial evaluating a nutrition-based intervention to lower cardiovascular r…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Braining- Aerobic Physical Activity as Add on Treatment in Bipolar Depression [NA]
A clinical trial evaluating aerobic physical activity as an add-on treatment for bipolar depression. The study is currently suspended.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Deep Brain Stimulation of Treatment-Resistant Bipolar Depression [NA]
This clinical trial is currently recruiting to evaluate deep brain stimulation for treatment-resistant bipolar depression.
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: FMRI of Patients Receiving IV Ketamine for Treatment Resistant Bipolar Depression [Phase 2]
Phase 2 trial evaluating intravenous ketamine with functional MRI in treatment-resistant bipolar depression. The study has completed.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: A Trial of the Fatty Acid Amide Hydrolase Inhibitor Palmitoylethanolamide in Bipolar Depression [Phase 2]
Phase 2 trial of palmitoylethanolamide for bipolar depression has completed.
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CLINICAL_TRIALS trial_result · 2025-08-12Clinical Trial Update: 8 Week Multi-site Study of MYDAYIS® for Bipolar Depression [Phase 2]
A Phase 2 multi-site study evaluating MYDAYIS for bipolar depression has completed.
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Acceptability & Safety of Two Sequential Doses of Psilocybin in Bipolar Disorder II Depression and Suicidality [Phase 2]
Phase 2 clinical trial evaluating the safety and acceptability of two sequential psilocybin doses in Bipolar Disorder Type II with depressio…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients [Phase 3]
This document reports an ongoing Phase 3 multicenter trial evaluating lumateperone for pediatric bipolar depression. Recruitment is currentl…
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CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Ketamine Associated ACC GABA and Glutamate Change and Depression Remission: [EARLY_Phase 1]
This early-phase trial reports ketamine-associated changes in ACC GABA and glutamate and notes depression remission. The study targets major…
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CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Efficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression [NA]
Clinical trial evaluating Temporal Interference Stimulation for efficacy and safety in bipolar depression; currently recruiting with no resu…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Mechanism of Action of Electroconvulsive Therapy
A completed clinical trial from Massachusetts General Hospital studying the mechanism of action of electroconvulsive therapy in unipolar and…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression [Phase 1, Phase 2]
This clinical trial from Laureate Institute for Brain Research is studying whether a brief bout of exercise combined with ibuprofen affects …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: A Pilot Study Investigating the Efficacy of Minocycline and N-Acetyl Cysteine for Bipolar Depression [Phase 4]
A Phase 4 pilot study evaluating the efficacy of minocycline and N-acetylcysteine for bipolar depression has been suspended.
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: SYNCED - SYNChronized Eating in Bipolar Depression Study [NA]
A not-yet-recruiting clinical trial named SYNCED is investigating synchronized eating as an intervention for bipolar depression, including B…