Bipolar Depression
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: 12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression [Phase 2]
A Phase 2 trial evaluating adjunctive infliximab for bipolar depression has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-02Clinical Trial Update: Cannabidiol as an Adjunctive Treatment for Bipolar Depression [Phase 2, Phase 3]
A phase 2/3 clinical trial evaluating cannabidiol as an adjunctive treatment for bipolar depression was terminated.
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CLINICAL_TRIALS trial_result · 2021-05-25Clinical Trial Update: Sequential Therapy for the Treatment of Severe Bipolar Depression. [Phase 2]
Phase 2 clinical trial update for sequential therapy in severe bipolar depression has completed enrollment with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-19Clinical Trial Update: Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression [Phase 2]
Phase 2 study assessing efficacy, safety, and pharmacokinetics of inhaled esketamine for treatment-resistant bipolar depression has been com…
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CLINICAL_TRIALS trial_result · 2020-10-06Clinical Trial Update: 18F-DOPA PET to Elucidate the Antidepressant Mechanism of Lurasidone in Bipolar Disorder [Phase 4]
Phase 4 trial updating the use of 18F-DOPA PET to understand how lurasidone may exert antidepressant effects in bipolar depression; results …
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CLINICAL_TRIALS trial_result · 2020-04-09Clinical Trial Update: NeoSync TMS Treatment for Bipolar I Depression [Phase 2]
Phase 2 trial update for NeoSync TMS treatment in bipolar depression has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Bright Light Therapy in the Treatment of Non-seasonal Bipolar Depression [Phase 1, Phase 2]
Clinical trial update on bright light therapy for non-seasonal bipolar depression, spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2020-01-18Clinical Trial Update: Ketamine as an Adjunctive Therapy for Major Depression [Phase 1]
Phase 1 trial update on ketamine as an adjunctive therapy for major depression; completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-12-26Clinical Trial Update: A Prophylactic Trial of Omega-3 Polyunsaturated Fatty Acids in Bipolar Disorder [Phase 2]
Phase 2 trial update on prophylactic omega-3 fatty acids in bipolar depression; study completed.
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CLINICAL_TRIALS trial_result · 2019-12-19Clinical Trial Update: Pediatric Open-Label Extension Study [Phase 3]
Phase 3 pediatric open-label extension study completed; results posted in 2019 for schizophrenia and autism conditions.
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression [Phase 3]
Phase 3 clinical trial evaluating minocycline and celecoxib as adjunctive treatments for bipolar depression has completed.
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CLINICAL_TRIALS trial_result · 2019-07-25Clinical Trial Update: A Phase III Study of SM-13496 in Patients With Bipolar I Depression. [Phase 3]
Phase III study of SM-13496 in bipolar I depression completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Nitrous TRD Bipolar Depression [EARLY_Phase 1]
Early-phase trial update for nitrous oxide in treatment-resistant bipolar disorder and bipolar depression; study terminated with results pos…
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CLINICAL_TRIALS trial_result · 2019-03-13Clinical Trial Update: Brexpiprazole for Bipolar Depression [Phase 4]
Phase 4 clinical trial update for brexpiprazole in bipolar depression; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-03-01Clinical Trial Update: Taurine as an Anti-Manic Agent: A Double-Blind, Placebo-Controlled Study [Phase 2]
Phase 2 double-blind, placebo-controlled trial evaluating taurine as an anti-manic agent in bipolar disorder with mania.
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: Vortioxetine add-on Treatment Improves the Symptoms in Patients With Bipolar Depression [Phase 2]
A Phase 2 trial evaluating vortioxetine as an add-on therapy shows improvement in symptoms for patients with bipolar depression.
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: Vitamin D Supplementation for Bipolar Depression [NA]
This entry reports the completion and posting of results for a clinical trial evaluating vitamin D supplementation in individuals with bipol…
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CLINICAL_TRIALS trial_result · 2018-03-12Clinical Trial Update: Uridine Adolescent Bipolar Depression Randomized Controlled Trial [NA]
This ClinicalTrials.gov entry notes that the randomized controlled trial of uridine for adolescent bipolar depression completed and results …
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CLINICAL_TRIALS trial_result · 2017-12-20Clinical Trial Update: Lurasidone Pediatric Bipolar Study [Phase 3]
Phase 3 trial update for lurasidone in pediatric bipolar I depression has completed, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: Biosignatures of Latuda for Bipolar Depression [NA]
A completed clinical trial evaluating biosignatures of Latuda (lurasidone) for bipolar depression, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-11-08Clinical Trial Update: Minocycline and Aspirin in the Treatment of Bipolar Depression [Phase 3]
Phase 3 trial evaluating minocycline and aspirin for bipolar depression has completed; results posted.
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CLINICAL_TRIALS trial_result · 2017-10-30Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Repeat Doses of GSK1014802. [Phase 1]
Phase 1 clinical trial update shows safety, tolerability, and pharmacokinetics of repeat doses of GSK1014802. The study has completed in par…
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CLINICAL_TRIALS trial_result · 2017-07-31Clinical Trial Update: Medication, Weight Gain and GI Hormones [Phase 4]
A Phase 4 clinical trial conducted by Vanderbilt University in bipolar depression studied a medication's effects on weight gain and gastroin…
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CLINICAL_TRIALS trial_result · 2017-05-30Clinical Trial Update: A Study To Investigate The Antidepressant Effect Of Lamotrigine In Patients With Bipolar Disorder Using Lithium [Phase 3]
Phase 3 study evaluating whether adding lamotrigine to lithium improves depressive symptoms in bipolar disorder, including bipolar depressio…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Simvastatin Augmentation of Lithium Treatment in Bipolar Depression [Phase 2]
This Phase 2 clinical trial update reports results for simvastatin augmentation of lithium in bipolar depression; the study (NCT01665950) wa…