B-cell Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-04-04Clinical Trial Update: Clinical Trial to Evaluate the Safety and Efficacy of IM19 CAR-T Cells in Patients With Relapsed and Refractory (R/R) B-cell Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Clinical trial update on IM19 CAR-T cells evaluating safety and efficacy in relapsed/refractory B-cell acute lymphoblastic leukemia (ALL) ac…
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CLINICAL_TRIALS trial_result · 2021-12-20Clinical Trial Update: Allogeneic CD19 CAR-T Cells for the Treatment of Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Clinical trial update on allogeneic CD19 CAR-T cells for relapsed/refractory B-cell acute lymphoblastic leukemia (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2021-11-22Clinical Trial Update: Study of Efficacy and Safety of CTL019 in Pediatric ALL Patients [Phase 2]
Phase 2 trial update on efficacy and safety of CTL019 (tisagenlecleucel) in pediatric B-cell acute lymphoblastic leukemia has completed with…
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CLINICAL_TRIALS trial_result · 2021-09-30Clinical Trial Update: Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell Malignancies [Phase 1, Phase 2]
Clinical trial update on combining acalabrutinib (ACP-196) with ACP-319 for B-cell malignancies, including non-Hodgkin lymphoma, multiple my…
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CLINICAL_TRIALS trial_result · 2021-04-13Clinical Trial Update: Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 study assessing the combination of chemotherapy with inotuzumab ozogamicin in patients with B-cell acute lymphoblastic leukemia, inc…
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CLINICAL_TRIALS trial_result · 2021-02-10Clinical Trial Update: Induced-T Cell Like NK Cells for B Cell Malignancies [Phase 1, Phase 2]
A clinical trial update for induced-T cell like NK cells targeting B cell malignancies is underway in Phase 1/Phase 2, with unspecified curr…
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CLINICAL_TRIALS trial_result · 2021-02-04Clinical Trial Update: A Clinical Study Evaluating the Safety and Efficacy of BinD19 Treatment in R/R ALL and Lymphoma Subjects [Phase 1, Phase 2]
A clinical trial update for a study evaluating BinD19 treatment in relapsed/refractory B-cell ALL and B-cell lymphoma across Phase 1 and Pha…
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CLINICAL_TRIALS trial_result · 2021-02-01Clinical Trial Update: CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL) [Phase 1, Phase 2]
Phase 1/2 trial updates for AUTO3 (CD19/22 CAR T cells) in B-cell acute lymphoblastic leukemia, including recurrent/refractory pediatric cas…
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Dual Target CAR-T Cells in B-cell Acute Lymphoblastic Leukemia [Phase 1, Phase 2]
Phase 1/2 trial update for dual-target CAR-T cells in B-cell acute lymphoblastic leukemia (B-ALL) with relapse/refractory disease, status no…
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CLINICAL_TRIALS trial_result · 2020-11-23Clinical Trial Update: Study of Efficacy and Safety of CTL019 in Pediatric ALL Patients [Phase 2]
Phase 2 trial update on CTL019 (tisagenlecleucel) for pediatric B-cell acute lymphoblastic leukemia, including relapsed/refractory cases, wi…
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CLINICAL_TRIALS trial_result · 2020-09-01Clinical Trial Update: Study of IFN-α Combined With CAR-T Cell Therapy in Relapsed and Refractory Acute Lymphoblastic Leukemia（R/R-ALL） [Phase 2]
Phase 2 trial evaluating IFN-α combined with CAR-T cell therapy for relapsed/refractory B-cell acute lymphoblastic leukemia.
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CLINICAL_TRIALS trial_result · 2019-12-11Clinical Trial Update: Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial update for autologous CAR-T/TCR-T cell immunotherapy targeting multiple malignancies; current status is unknown.
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CLINICAL_TRIALS trial_result · 2019-05-24Clinical Trial Update: Study of Redirected Autologous T Cells Engineered to Contain Anti-CD19 Attached to TCR and 4-1BB Signaling Domains in Patients With Chemotherapy Resistant or Refractory Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating redirected autologous T cells engineered with anti-CD19, TCR, and 4-1BB signaling in chemotherapy-resistant or refr…
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CLINICAL_TRIALS trial_result · 2018-12-07Clinical Trial Update: A Feasibility and Safety Study of CD38 CAR-T Cell Immunotherapy for Relapsed B-cell Acute Lymphoblastic Leukemia After CD19 CAR-T Adoptive Cellular Immunotherapy [Phase 1, Phase 2]
Feasibility and safety study of CD38 CAR-T cell therapy for relapsed B-cell acute lymphoblastic leukemia following CD19 CAR-T, conducted in …
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CLINICAL_TRIALS trial_result · 2018-06-29Clinical Trial Update: CD19-CAR-T Cells in Patients With R/R B-ALL [Phase 1]
This Clinical Trial Update describes a Phase 1 study of CD19-CAR-T cells in patients with relapsed/refractory B-cell acute lymphoblastic leu…
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CLINICAL_TRIALS trial_result · 2018-02-27Clinical Trial Update: Multi-centric Study [Phase 2]
Phase 2 multi-center trial in B-cell acute lymphoblastic leukemia with refractory disease and CD22+ expression has completed; sponsored by N…
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CLINICAL_TRIALS trial_result · 2018-01-05Clinical Trial Update: CART-19 Cells For R/R B-ALL [Phase 2, Phase 3]
Clinical trial update for CART-19 cell therapy in relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL) across Phase 2 and Phase 3…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia
This completed clinical trial update reports cognitive and brain-function outcomes in children treated with methotrexate for acute lymphobla…
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CLINICAL_TRIALS trial_result · 2017-05-22Clinical Trial Update: Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma [Phase 2]
Phase 2 trial evaluating rituximab in patients undergoing donor peripheral blood stem cell transplantation for relapsed or refractory B-cell…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia [Phase 3]
A Phase 3 trial updated on dosing of vincristine (low-dose vs high-dose) plus combination chemotherapy for relapsed B-cell acute lymphoblast…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update evaluating whether adding donor stem cell transplantation to combination chemotherapy improves outcomes in adu…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Genetically Modified Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 trial evaluating genetically modified haploidentical natural killer cell infusions for B-lineage acute lymphoblastic leukemia has co…
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy [Phase 1]
Phase 1 trial evaluating CART19 therapy for B-cell hematologic malignancies including various lymphomas and leukemias that are refractory or…
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CLINICAL_TRIALS trial_result · 2017-01-16Clinical Trial Update: Ibrutinib in Treating Patients With Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia [Phase 2]
This clinical trial update reports the termination of a Phase 2 study of ibrutinib in adults with relapsed or refractory B-cell acute lympho…
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CLINICAL_TRIALS trial_result · 2016-11-18Clinical Trial Update: A Phase I Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Leukemia [Phase 1]
Update on a Phase I trial of 4SCAR19 cells for relapsed/refractory B-cell acute lymphoblastic leukemia. The trial status is currently UNKNOW…