B-cell Acute Lymphoblastic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Efficacy of Short-course Blinatumomab for MRD Erradication in B-ALL [Phase 2]
Phase 2 clinical trial evaluating short-course blinatumomab for eradication of measurable residual disease in B-cell acute lymphoblastic leu…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Bridging Allogeneic Hematopoietic Stem Cell Transplantation or Not After CD19 CAR - T (S1904) Cell Therapy for r/r B-cell Acute Lymphoblastic Leukemia [NA]
A clinical trial (S1904) from Peking University People's Hospital is investigating whether to bridge to allogeneic hematopoietic stem cell t…
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CLINICAL_TRIALS research · 2025-02-25Clinical Trial Update: a Clinical Research of CD19 and CD22 Targeted Prime CAR-T Cell in Relapsed/Refractory B-ALL [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a CD19 and CD22-targeted Prime CAR-T cell therapy for relapsed or refractory B-cell acute lymphoblasti…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Newly-diagnosed Intermediate/High Risk Pediatric B-cell ALL Protocol [Phase 2, Phase 3]
A multicenter Phase 2/3 pediatric trial protocol for newly diagnosed intermediate/high risk B-cell acute lymphoblastic leukemia is currently…
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Donor Derived CD19 CAR-T Cells in the Treatment of R/R B-cell Acute Lymphoblastic Leukemia [EARLY_Phase 1]
A Phase 1 trial evaluating donor-derived CD19 CAR-T cells for relapsed/refractory B-cell acute lymphoblastic leukemia is currently recruitin…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Inaticabtagene Autoleucel (Inati-cel; CNCT19) Treatment for Newly Diagnosed B-cell ALL Patients in CR1 [Phase 2]
Phase 2 study of Inati-cel (Inaticabtagene Autoleucel) for newly diagnosed B-cell acute lymphoblastic leukemia in CR1 is not yet recruiting.
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: CAR-T-19 Injection in the Treatment of CD19-positive Relapsed/Refractory B-ALL [Phase 2]
A Phase 2 clinical trial evaluating CAR-T-19 therapy for CD19-positive relapsed or refractory B-cell acute lymphoblastic leukemia is current…
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CLINICAL_TRIALS research · 2025-01-13Clinical Trial Update: Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 clinical trial update on locally manufactured CAR T-cell products for multiple B-cell malignancies, including B-cell lymphoma and B-…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Allogeneic CD19-targeted CAR-γδT Cell Infusion Therapy in Relapsed/Refractory B Cell Acute Lymphoblastic Leukemia [EARLY_Phase 1]
Early-phase clinical trial of allogeneic CD19-targeted CAR-γδT cell infusion therapy for relapsed/refractory B-cell acute lymphoblastic leuk…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALL [Phase 2]
Phase 2 clinical trial evaluating maintenance therapy with decitabine, venetoclax, and blinatumomab after hematopoietic stem cell transplant…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies [Phase 1]
Phase 1 study of VIP943 in adults with advanced CD123+ hematologic malignancies is currently recruiting, including acute myeloid leukemia, B…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: JY231(JY231) Injection for the Treatment of Relapsed or Refractory B Cell Lymphoma/ Leukemia [NA]
Clinical trial update for JY231 Injection studying its use in relapsed or refractory B-cell lymphoma and B-cell acute lymphoblastic leukemia…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Safety and Efficacy of PRG-2302 for Refractory or Relapsed B-cell Acute Lymphoblastic Leukemia Disease. [EARLY_Phase 1]
An early-phase trial evaluating the safety and efficacy of PRG-2302 for refractory or relapsed B-cell acute lymphoblastic leukemia, currentl…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Blinatumomab as Maintenance Therapy in Patients With High-risk B-lineage Acute Lymphoblastic Leukemia Post Allogeneic Hematopoietic Cell Transplantation [NA]
Trial evaluating Blinatumomab as maintenance therapy for high-risk B-cell acute lymphoblastic leukemia after allogeneic hematopoietic cell t…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Clinical Research of CD19 Targeted CAR-T Cell in Relapsed/ Refractory B-ALL [Phase 1]
Phase 1 clinical trial evaluating CD19-targeted CAR-T cell therapy for relapsed/refractory acute lymphoblastic leukemia.
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: Safety and Efficacy of CAR T Cell Therapy in Patients with R/r B-ALL [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating the safety and efficacy of an unnamed CAR T cell therapy in patients with relapsed or refractory B-…
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CLINICAL_TRIALS research · 2024-09-23Clinical Trial Update: Efficacy Study of Blinatumomab Clean Up Early Residual Disease for Newly Diagnosed Pediatric B Lymphoblastic Leukemia [Phase 2, Phase 3]
This clinical trial update outlines a Phase 2/3 efficacy study of blinatumomab for newly diagnosed pediatric B-cell acute lymphoblastic leuk…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Inaticabtagene Autoleucel Injection Treatment for Adult Relapsed or Refractory Acute Lymphocytic Leukemia
The trial update indicates that Inaticabtagene Autoleucel is being studied for adults with relapsed or refractory B-cell acute lymphoblastic…
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CLINICAL_TRIALS research · 2024-08-28Clinical Trial Update: Pilot CAR-T Cells Therapy for Children/Young Adults With CD19+ R/R Leukemia/Lymphoma [Phase 1]
A Phase 1 trial in Belarus is evaluating a pilot CD19-targeted CAR-T cell therapy for children and young adults with relapsed/refractory B-c…
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CLINICAL_TRIALS research · 2024-08-19Clinical Trial Update: Hema-NeoTIL01 Cell Infusion Therapy in Relapsed/Refractory Acute Leukemia [EARLY_Phase 1]
This is an early Phase 1 trial update for Hema-NeoTIL01 cell infusion therapy in relapsed/refractory acute leukemia, including acute myeloid…
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CLINICAL_TRIALS research · 2024-08-15Clinical Trial Update: Blinatumomab Plus Venetoclax Sequenced With Inotuzumab Ozogamicin in Treating B-ALL [Phase 2]
Phase 2 study evaluating sequencing of Blinatumomab, Venetoclax, and Inotuzumab Ozogamicin for B-cell acute lymphoblastic leukemia is curren…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: CD19 & CD20 Bispecific CAR T Cells for Relapsed / Refractory B Cell Hematological Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a CD19 and CD20 bispecific CAR T cell therapy for relapsed or refractory B-cell hematologic malignancies…
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CLINICAL_TRIALS research · 2024-07-16Clinical Trial Update: The Use of Blinatumomab in Patients With NGS-MRD Relapsed B-ALL After Autologous/Allogeneic Transplantation [NA]
Clinical trial evaluating blinatumomab for patients with NGS-MRD positive relapsed B-cell acute lymphoblastic leukemia after autologous or a…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Combination of an Anti-PD1 Antibody With Tisagenlecleucel Reinfusion in Children, Adolescents and Young Adults With Acute Lymphoblastic Leukemia After Loss of Persistence [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating reinfusion of tisagenlecleucel in combination with an anti-PD1 antibody for children, adolescents, and…
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CLINICAL_TRIALS research · 2019-02-04Clinical Trial Update: Evaluation of ProALL miRs in Blood Specimen for Prediction of ALL Relapse Risk
Clinical trial update evaluating ProALL microRNAs in blood to predict relapse risk in B-cell acute lymphoblastic leukemia.