Autosomal Dominant Polycystic Kidney Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: NOX4 and Related Biomarkers in ADPKD
A Mayo Clinic-sponsored clinical trial (NCT04630613) is recruiting to investigate NOX4 and related biomarkers in Autosomal Dominant Polycyst…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Canadian Medical Assessment of JINARC™ Outcomes Registry
Completed Canadian medical assessment of the JINARC outcomes registry for autosomal Dominant Polycystic Kidney Disease.
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Descriptive Analysis of Preimplantation Genetic Test (PGT)in Couples With Polycystic Kidney Disease (PKD). In the ADPKD Subgroup Evaluation of Outcomes and Complications Comparing Couples in Which the Father is Affected With Couples in Which the Mother is Affected
This completed clinical trial update provides a descriptive analysis of preimplantation genetic testing (PGT) in couples affected by autosom…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Bempedoic Acid Therapy for Polycystic Kidney Disease [Phase 2]
A Phase 2 clinical trial is evaluating bempedoic acid for autosomal dominant polycystic kidney disease; the study status is not yet recruiti…
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Post-Marketing Surveillance Study of Tolvaptan in Patients With ADPKD
Post-marketing surveillance study of tolvaptan in autosomal dominant polycystic kidney disease has completed and posted its results.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Hypertension in Children and Young People at Risk of Autosomal Dominant Polycystic Kidney Disease
A King’s College London–led clinical trial is recruiting to study hypertension in children and young people at risk of autosomal dominant po…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD) [Phase 4]
Phase 4 trial update on empagliflozin for Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD). The study is currently active but not rec…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Somatosensory Phenotyping of ADPKD
A clinical trial is currently recruiting to study somatosensory phenotyping in autosomal dominant polycystic kidney disease (ADPKD), with a …
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CLINICAL_TRIALS research · 2025-10-27Clinical Trial Update: Role of ROS and cAMP-PKA Biomarkers in ADPKD
Clinical trial update examining reactive oxygen species (ROS) and cAMP-PKA biomarkers in autosomal dominant polycystic kidney disease (ADPKD…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Drug-Drug Interaction of JMKX003142 With Amiodarone and Febuxostat in Healthy Subjects [Phase 1]
Phase 1 clinical trial assessing potential drug-drug interaction between JMKX003142 and amiodarone and febuxostat in healthy subjects; the l…
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CLINICAL_TRIALS research · 2025-09-12Clinical Trial Update: Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease [Phase 2]
A Phase 2 clinical trial is evaluating the short-term effects of an SGLT2 inhibitor on divalent ion levels in autosomal dominant polycystic …
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: Outcome of ADPKD With Octreotide LAR
An update on a clinical trial evaluating octreotide long-acting release for autosomal dominant polycystic kidney disease (ADPKD). The trial …
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Simulated and Synthetic Health Data: Improving Clinical Research on Rare Diseases. A Real-World Data Simulation of Autosomal Dominant Polycystic Kidney Disease (ADPKD) Trials. A Retrospective, Observational Study
A real-world data simulation and retrospective observational study is described to improve clinical research for Autosomal Dominant Polycyst…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Renal Oxygen Consumption, Insulin Sensitivity, and Daily Caloric Restriction in ADPKD [NA]
Update on an active-not-recruiting clinical trial in autosomal dominant polycystic kidney disease examining renal oxygen consumption, insuli…
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CLINICAL_TRIALS trial_result · 2025-08-17Clinical Trial Update: Treatment of Vascular Stiffness in ADPKD [Phase 4]
A Phase 4 clinical trial evaluating treatments for vascular stiffness in autosomal dominant polycystic kidney disease has completed.
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Daily Caloric Restriction in ADPKD [NA]
This clinical trial update reports that a study evaluating daily caloric restriction for Autosomal Dominant Polycystic Kidney Disease is cur…
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EMA approval · 2025-08-08EMA Authorised: Jinarc (tolvaptan) — Otsuka Pharmaceutical Netherlands B.V.
The EMA has authorised Jinarc (tolvaptan) for autosomal dominant polycystic kidney disease under the MAH Otsuka Pharmaceutical Netherlands B…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Effects on Blood and Urine Markers of Single Ascending Dose of GSK4771261 in Healthy Participants and Participants With Autosomal Dominant Polycystic Kidney Disease [Phase 1]
A Phase 1 study to evaluate the safety, tolerability, and effects on blood and urine markers of a single ascending dose of GSK4771261 in hea…
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CLINICAL_TRIALS trial_result · 2025-08-06Clinical Trial Update: Pravastatin and Alkali Therapy in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
A Phase 2 clinical trial evaluating pravastatin with alkali therapy in adults with autosomal dominant polycystic kidney disease has complete…
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CLINICAL_TRIALS trial_result · 2025-07-24Clinical Trial Update: Samsca PMS in ADPKD Patients
A completed post-marketing safety surveillance study of Samsca (tolvaptan) in patients with autosomal dominant polycystic kidney disease.
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Trial of JMKX003142 in Participants With Rapidly Progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) [Phase 2]
The document provides a status update on a Phase 2 clinical trial evaluating JMKX003142 for rapidly progressive autosomal dominant polycysti…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Autosomal Dominant Polycystic Kidney Disease (ADPKD) Study
Clinical trial update shows recruitment for an Autosomal Dominant Polycystic Kidney Disease (ADPKD) study sponsored by Children's Hospital o…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease [NA]
This completed clinical trial evaluated the effect of beetroot juice on reducing hypertension in autosomal dominant polycystic kidney diseas…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Study of RGLS8429 in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 1]
This Phase 1 trial update reports the completion of a study evaluating the safety and pharmacology of RGLS8429 in adults with autosomal domi…
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CLINICAL_TRIALS trial_result · 2025-05-13Clinical Trial Update: Feasibility of Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease [Phase 2]
Phase 2 feasibility study of empagliflozin in autosomal dominant polycystic kidney disease; the trial is currently active but not recruiting…