Aplastic Anemia
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy [NA]
This ClinicalTrials.gov entry describes a pediatric stem cell transplant and cellular therapy trial evaluating a family health communication…
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: A Prediction Model in Pregnant Women With Aplastic Anemia
This ClinicalTrials.gov entry describes a prospective study evaluating a prediction model for outcomes in pregnant women with aplastic anemi…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: ATGAM General Investigation
Pfizer's ATGAM anti-thymocyte globulin trial for aplastic anemia is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2025-10-30Clinical Trial Update: Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion [NA]
Clinical trial update from Baylor College of Medicine reports results for haploidentical hematopoietic cell transplantation using TCR alpha/…
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CLINICAL_TRIALS trial_result · 2025-10-24Clinical Trial Update: REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy [Phase 1]
Phase 1 trial of REGN7257 in adults with severe aplastic anemia refractory to or relapsed on immunosuppressive therapy has been terminated.
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CLINICAL_TRIALS trial_result · 2025-10-23Clinical Trial Update: Methadone as an Alternative Treatment for Children Underdoing HSCT [Phase 3]
Phase 3 trial evaluating methadone as an alternative treatment for children undergoing hematopoietic stem cell transplantation; the study is…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Umbilical Cord Blood Transplantation From Unrelated Donors
This is an ongoing clinical trial evaluating umbilical cord blood transplantation from unrelated donors for hematologic diseases. The study …
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)
The document announces a new clinical trial called HALO-SCT, assessing high-altitude observation in stem cell transplantation. It is current…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies [EARLY_Phase 1]
An early-phase trial evaluating Darzalex Faspro (daratumumab and hyaluronidase-fihj) given before desensitization and allogeneic stem cell t…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Modified Transplantation Regimen and aGVHD Prophylaxis for Severe Aplastic Anemia in the Setting of Allogeneic HSCT.
This clinical trial reports results on a modified transplantation regimen and acute graft-versus-host disease prophylaxis for patients with …
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CLINICAL_TRIALS trial_result · 2025-09-16Clinical Trial Update: Efficacy and Safety in Transfusion Independent Non-severe Aplastic Anemia [Phase 2]
Phase 2 trial results evaluating efficacy and safety in transfusion-independent non-severe aplastic anemia.
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Long Term Follow-up Observational Study After Clinical Trials of AMG531 (Romiplostim) in Patients With Untreated Aplastic Anemia
A long-term follow-up observational study of Romiplostim (AMG531) in patients with untreated aplastic anemia, building on prior clinical tri…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Multi-omics Profiling of Patients With Aplastic Anemia Before and After CD7-CAR-T Therapy
The study profiles multi-omics data from patients with aplastic anemia before and after CD7-CAR-T therapy to understand treatment-related bi…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Assesment of Treatment Outcomes of Aquired Aplastic Anemia in Children : A Retrospective and Prospective Cohort
A trial update from Assiut University describing a retrospective and prospective cohort study on treatment outcomes for acquired aplastic an…
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: T Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation Conditioned With a Reduced Intensity Regimen in Patients With Hematologic Malignancies and Aplastic Anemia [Phase 1]
Phase 1 study evaluating T cell-depleted allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning in patients …
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
This document provides an update on a phase 1/2 clinical trial evaluating CD34+ stem cell selection for patients receiving allogeneic stem c…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Umbilical Cord Blood-Supported Haplo-HSCT for Aplastic Anemia Treatment Study [NA]
Recruiting clinical trial assessing umbilical cord blood-supported haploidentical hematopoietic stem cell transplantation for treating aplas…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion [Phase 2]
A Phase 2 clinical trial evaluating allogeneic stem cell transplantation with alpha/beta T cell and CD19+ B cell depletion for malignant and…
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CLINICAL_TRIALS other · 2025-08-05Clinical Trial Update: Reproductive and Mental Health of Patients With Aplastic Anemia
Clinical trial update announcing ongoing recruitment to study reproductive and mental health in patients with aplastic anemia. Sponsored by …
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia [Phase 1]
A Phase 1 clinical trial evaluating CD7 CAR T cells (RD13-02) for relapsed/refractory severe aplastic anemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Efficacy and Safety of UCBT With TMI -Based Conditioning Regimen for Adults With Refractory/Relapsed Aplastic Anemia [Phase 2]
Phase 2 clinical trial evaluating Umbilical Cord Blood Transplant with a TMI-based conditioning regimen for adults with refractory or relaps…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplastic Anemia [Phase 2]
A Phase 2 trial evaluating eltrombopag in combination with immunosuppressive therapy for East-Asian patients with severe aplastic anemia has…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Haploidentical HCT for Severe Aplastic Anemia [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating haploidentical hematopoietic cell transplantation for severe aplasti…
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CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children [Phase 2]
A Phase 2 clinical trial at Johns Hopkins All Children's Hospital is evaluating TCR alpha-beta T-cell-depleted haploidentical hematopoietic …
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. [Phase 2]
Phase 2 trial evaluating hematopoietic cell transplantation with reduced-intensity conditioning and post-transplant cyclophosphamide for sev…