Apical Periodontitis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Accuracy of PoCT to ELISA by Detecting Human IL-6 in Teeth with Apical Periodontitis
A clinical trial evaluating the accuracy of point-of-care testing versus ELISA by detecting human IL-6 in teeth affected by apical periodont…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Comparison of Post-operative Pain After Use of Endo-activator and Conventional Irrigation During Endodontic Treatment in Symptomatic Periapical Periodontitis [NA]
A completed clinical trial comparing EndoActivator sonic activation with conventional irrigation during endodontic treatment for symptomatic…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Effect of Cryotherapy and Laser Application on Post-Operative Pain in Single Visit Endodontically Treated Symptomatic Apical Periodontitis Cases [NA]
Clinical trial assessed the effect of cryotherapy and laser application on postoperative pain after single-visit endodontic treatment of irr…
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CLINICAL_TRIALS research · 2024-10-17Clinical Trial Update: Comparative Evaluation of Antimicrobial Efficacy, Clinical and Radiographic Success of Calcium Hydroxide, Chlorhexidine, and Modified Triple Antibiotic Paste in Different Combination Forms As Intracanal Medicaments Against Enterococcus Faecalis in Primary Teeth [NA]
This clinical trial protocol compares calcium hydroxide, chlorhexidine, and modified triple antibiotic paste as intracanal medicaments for E…
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CLINICAL_TRIALS withdrawal · 2024-10-15Clinical Trial Update: Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General [Phase 2]
Phase 2 trial comparing Kovanaze nasal spray with Articaine for pulpal anesthesia in maxillary teeth has been withdrawn.
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: The Efficacy of Two Different Irrigation Methods on PGE2, NO and IL-6 Levels [NA]
This update reports the results of a completed trial comparing two irrigation methods and their effects on inflammatory markers (PGE2, NO, I…
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: The Effect of Ca(OH)2 in Apical Periodontitis [NA]
A completed clinical trial evaluating the effect of calcium hydroxide in apical periodontitis and its use as an intracanal medicament, inclu…
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CLINICAL_TRIALS trial_result · 2024-10-03Clinical Trial Update: Sclerostin Regulation in Apical Periodontitis Lesions in Apical Periodontitis Lesions
A completed clinical trial investigating sclerostin regulation in apical periodontitis lesions.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial. [Phase 1]
A Phase 1 randomized trial evaluating post-operative pain and IL-8 expression using ketorolac tromethamine versus cryoirrigation as the fina…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Outcome of Bone Window Approach in Endodontic Microsurgery Using Novel Piezoelectric Device [NA]
This clinical trial update reports on a bone window approach in endodontic microsurgery using a novel piezoelectric device, sponsored by the…
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CLINICAL_TRIALS research · 2024-08-29Clinical Trial Update: Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery [NA]
A clinical trial is investigating the effect of photobiomodulation on pain and healing after endodontic microsurgery in patients with apical…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment [Phase 4]
Phase 4 trial reports results on using ferumoxytol nanoparticles as an antibiofilm treatment for dental conditions, including apical periodo…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis [Phase 2, Phase 3]
A Phase 2/3 clinical trial is evaluating asiaticoside as an intracanal medication for teeth with apical periodontitis and is currently recru…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: Comparative Analysis of Photodynamic Therapy on Periapical Healing [NA]
This completed clinical trial evaluated photodynamic therapy for promoting periapical healing in apical periodontitis.
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Detection of Periapical Lesions on Dental Panoramic Radiographs Based on Artificial Intelligence
This clinical trial is evaluating an AI-based method to detect periapical lesions on dental panoramic radiographs. Sponsored by Centre Hospi…
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CLINICAL_TRIALS trial_result · 2024-07-09Clinical Trial Update: Periapical Healing in Response to Endodontically Treated Teeth With Different Sealing Cement [Phase 4]
A Phase 4 clinical trial is investigating periapical healing after endodontically treated teeth using different sealing cements in apical pe…
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CLINICAL_TRIALS research · 2024-07-03Clinical Trial Update: Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines [Phase 2, Phase 3]
Mansoura University is conducting a Phase 2/Phase 3 clinical trial to evaluate glycyrrhizin as an intracanal medicament for root canal disin…
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CLINICAL_TRIALS research · 2024-07-01Clinical Trial Update: Revitalization of Traumatized Immature Permanent Teeth
A clinical trial from Universitaire Ziekenhuizen KU Leuven is recruiting to study revitalization of traumatized immature permanent teeth in …
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: No Code Artificial Intelligence to Detect Radiographic Features Associated With Unsatisfactory Endodontic Treatment [NA]
Clinical trial update on a No Code AI tool intended to detect radiographic features associated with unsatisfactory endodontic treatment; the…
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CLINICAL_TRIALS research · 2024-06-20Clinical Trial Update: Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis [Phase 2, Phase 3]
An ongoing Phase 2/3 clinical trial at Mansoura University evaluates the effectiveness of a boswellia-based intracanal medicament compared w…
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CLINICAL_TRIALS research · 2024-06-06Clinical Trial Update: Effects of RCT on Periapical Healing, Inflammatory Markers, and Kidney Function Indicators in CKD Patients With AP [NA]
This clinical trial update describes a randomized controlled trial evaluating periapical healing, inflammatory markers, and kidney function …
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CLINICAL_TRIALS trial_result · 2024-06-03Clinical Trial Update: Association Between Apical Periodontitis and Psoriasis Vulgaris
A completed clinical trial from the University of Siena studied the association between apical periodontitis and psoriasis vulgaris. The stu…
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CLINICAL_TRIALS research · 2024-05-29Clinical Trial Update: Effect of Endodontic Treatment on Inflammatory Markers, Disease Activity and Periapical Healing in Rheumatoid Arthritis Patients With Apical Periodontitis : A Prospective Interventional Study [NA]
A prospective interventional study evaluating whether endodontic treatment affects inflammatory markers, rheumatoid arthritis disease activi…
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CLINICAL_TRIALS trial_result · 2024-05-09Clinical Trial Update: Influence of Sonic Activation of Root Sealers on Post-Operative Pain [NA]
Completed clinical trial evaluating the effect of sonic activation of root sealers on postoperative pain in apical periodontitis.
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: The Effects of EndoActivator on Postoperative Pain and Root Canal Treatment Success [NA]
A completed clinical trial update evaluating the EndoActivator device's effect on postoperative pain and root canal treatment success.