Aortic Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: Feasibility of Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic, Severe Aortic Stenosis [NA]
This clinical trial update notes the completion of a feasibility study evaluating transcatheter aortic valve replacement (TAVR) in low-risk …
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis [NA]
An update on the EARLY TAVR trial comparing transcatheter aortic valve replacement to surveillance in asymptomatic patients with severe aort…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Mechanism of Decompensation Evaluation - Aortic Stenosis
A completed University of Edinburgh clinical trial evaluating the mechanism of decompensation in aortic stenosis, with investigation into my…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: PARTNER 3 Trial - Aortic Valve-in-Valve [NA]
The PARTNER 3 trial investigating aortic valve-in-valve therapy sponsored by Edwards Lifesciences is currently recruiting.
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CLINICAL_TRIALS research · 2024-05-09Clinical Trial Update: Effect of PCSK9 Inhibitors on Calcific Aortic Valve Stenosis [Phase 3]
A Phase 3 clinical trial is evaluating the effect of PCSK9 inhibitors on calcific aortic valve stenosis and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: PERIGON Japan Trial [NA]
Clinical trial update for the PERIGON Japan trial has completed; results were posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-04-03Clinical Trial Update: Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure [Phase 4]
Phase 4 trial evaluating the effects of levosimendan on cardiac function after transcatheter aortic valve replacement in patients with heart…
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR). [Phase 4]
Phase 4 clinical trial examining glucocorticoid treatment in transcatheter aortic valve replacement (TAVR) to reduce conduction disturbances…
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: Comparison of Procedural Sedation With Propofol and Dexmedetomidine During Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 clinical trial comparing procedural sedation using propofol versus dexmedetomidine during transcatheter aortic valve implantation ha…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Association of Type of Anesthetic and Outcomes in Transfemoral Aortic Valve Replacement
Clinical trial assessing how the type of anesthesia influences outcomes in transfemoral aortic valve replacement for aortic stenosis has com…
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: Transmural Systems Transcaval Closure Device for Transcaval Access Ports During Transcatheter Aortic Valve Replacement [NA]
Trial update for a transcaval closure device used in transcaval access ports during transcatheter aortic valve replacement; study status ter…
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CLINICAL_TRIALS trial_result · 2023-01-05Clinical Trial Update: A Prospective Study of Fractional Flow Reserve Assessment of Intermediate Coronary Stenoses in Severe Aortic Stenosis [NA]
Clinical trial update on using fractional flow reserve to assess intermediate coronary stenoses in patients with severe aortic stenosis; the…
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CLINICAL_TRIALS trial_result · 2022-11-14Clinical Trial Update: AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation [Phase 3]
Phase 3 trial comparing anticoagulation versus acetylsalicylic acid after transcatheter aortic valve implantation is currently recruiting.
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CLINICAL_TRIALS trial_result · 2022-10-27Clinical Trial Update: IV Sodium Ferric Gluconate Complex in Patients Undergoing TAVI [Phase 4]
Phase 4 trial update for IV sodium ferric gluconate complex in patients undergoing transcatheter aortic valve implantation (TAVI).
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CLINICAL_TRIALS trial_result · 2022-09-15Clinical Trial Update: Study to Evaluate the Effect on Improvement of LVH by the Control of BP in Hypertension Patients With AV Disease [Phase 4]
Phase 4 clinical trial evaluating the effect of blood pressure control on improvement of left ventricular hypertrophy in hypertension patien…
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CLINICAL_TRIALS trial_result · 2022-07-27Clinical Trial Update: Perceval Sutureless Implant Versus Standard-Aortic Valve Replacement [NA]
A terminated clinical trial comparing Perceval sutureless aortic valve replacement with standard AVR; results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-07-20Clinical Trial Update: Inflammation and Thrombosis in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (TAVR) [Phase 4]
Phase 4 trial update on inflammation and thrombosis in patients with severe aortic stenosis after transcatheter aortic valve replacement (TA…
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CLINICAL_TRIALS trial_result · 2022-06-28Clinical Trial Update: Effect of Antifibrotic Therapy on Regression of Myocardial Fibrosis After Transcatheter Aortic Valve Implantation (TAVI) in Aortic Stenosis Patients With High Fibrotic Burden [Phase 3]
Phase 3 trial evaluating antifibrotic therapy to induce regression of myocardial fibrosis after TAVI in patients with severe aortic stenosis…
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CLINICAL_TRIALS trial_result · 2022-02-15Clinical Trial Update: Effect of Dapagliflozin on Myocardial and Renal Function Following Aortic Valve Stenosis Intervention [Phase 2, Phase 3]
Phase 2/3 trial investigating the effect of dapagliflozin on myocardial and renal function after aortic valve intervention.
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CLINICAL_TRIALS trial_result · 2021-12-02Clinical Trial Update: PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis [NA]
The PARTNER 3 trial evaluated the SAPIEN 3 transcatheter heart valve in low-risk patients with aortic stenosis, reporting on safety and effe…
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Transcatheter Aortic Valve Replacement Single Center Registry in Chinese Population [Phase 4]
Phase 4 registry update for transcatheter aortic valve replacement in Chinese population; condition is symptomatic aortic stenosis.
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CLINICAL_TRIALS trial_result · 2021-04-08Clinical Trial Update: PARTNER II Trial: S3iCAP [NA]
Clinical trial update for the PARTNER II trial (S3iCAP) related to aortic stenosis; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: Iron Supplementation in TAVI and SAVR Patients With Iron Deficiency [Phase 4]
Phase 4 trial update on iron supplementation in patients undergoing transcatheter or surgical aortic valve replacement with iron deficiency.
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis [Phase 3]
Phase 3 trial evaluating anti-thrombotic strategies after transcatheter aortic valve implantation in symptomatic aortic stenosis patients; s…
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis [NA]
A clinical trial evaluating the SAPIEN 3 Ultra System in intermediate-risk patients with symptomatic, severe aortic stenosis has completed a…