Aortic Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-09-24Clinical Trial Update: A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan) [NA]
A study evaluating transcatheter aortic valve therapy in dialysis patients with aortic stenosis in Japan has posted results.
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CLINICAL_TRIALS trial_result · 2020-09-14Clinical Trial Update: DEFLECT I: Keystone Heart Embolic Deflection Trial [NA]
Clinical trial update for the DEFLECT I study on embolic deflection in aortic stenosis; status completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese Population [NA]
Clinical trial update reporting safety and effectiveness results of Edwards Lifesciences' SAPIEN 3 transcatheter heart valve in the Chinese …
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: China XT: Safety and Effectiveness of Edwards Lifesciences SAPIEN XT THV in the Chinese Population [NA]
Clinical trial update reports on safety and effectiveness of Edwards SAPIEN XT transcatheter heart valve in Chinese patients with aortic ste…
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CLINICAL_TRIALS trial_result · 2020-05-28Clinical Trial Update: Pressure Assessment to Improve Outcomes After TAVR: a Registry [EARLY_Phase 1]
Early-phase registry trial assessing pressure measurement after TAVR to improve outcomes has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-04-30Clinical Trial Update: Effect of Preoperative Iron Isomaltoside 1000 Administration on Hemoglobin Concentration in Patients Undergoing Transcatheter Aortic Valve Implantation [Phase 4]
Phase 4 trial assessing whether preoperative iron isomaltoside 1000 improves hemoglobin in patients undergoing transcatheter aortic valve im…
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CLINICAL_TRIALS research · 2020-01-18Clinical Trial Update: Assessment of Osteoblastic Activity With 18F-Fluoride in Aortic Bioprosthesis Structural Valve Dysfunction (SVD) [Phase 4]
A Phase 4 trial evaluating osteoblastic activity using 18F-Fluoride imaging in patients with structural valve dysfunction of aortic bioprost…
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CLINICAL_TRIALS trial_result · 2019-12-27Clinical Trial Update: ProspeCtive, nOn-randoMized, MulticENter Clinical Evaluation of Edwards Pericardial Bioprostheses With a New Tissue Treatment Platform (COMMENCE) [NA]
A prospective, non-randomized, multicenter evaluation of Edwards pericardial bioprostheses using a new tissue treatment platform (COMMENCE) …
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CLINICAL_TRIALS trial_result · 2019-11-08Clinical Trial Update: EDWARDS INTUITY Elite Valve System
Clinical trial update for the Edwards INTUITY Elite Valve System showing completed status with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-14Clinical Trial Update: EDWARDS INTUITY Valve System FOUNDATION Study
Clinical trial update for the Edwards INTUITY Valve System FOUNDATION study; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-09-17Clinical Trial Update: Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Severe, Symptomatic Aortic Stenosis in Intermediate Risk Subjects Who Need Aortic Valve Replacement (SURTAVI). [NA]
This clinical trial update describes the SURTAVI study evaluating the safety and efficacy of Medtronic's CoreValve System for severe symptom…
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CLINICAL_TRIALS trial_result · 2019-09-10Clinical Trial Update: REPRISE II: REpositionable Percutaneous Replacement of Stenotic Aortic Valve Through Implantation of Lotus™ Valve System [NA]
A completed clinical trial update for the REPRISE II study evaluating repositionable percutaneous replacement of a stenotic aortic valve usi…
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CLINICAL_TRIALS trial_result · 2019-07-30Clinical Trial Update: Safety and Efficacy Study of Lotus Valve for Transcatheter Aortic Valve Replacement [NA]
Clinical trial update for the Lotus Valve in transcatheter aortic valve replacement (TAVR) shows terminated status with results posted.
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CLINICAL_TRIALS trial_result · 2019-04-29Clinical Trial Update: Neuroprotection in Patients Undergoing Aortic Valve Replacement [NA]
Clinical trial updating neuroprotection during aortic valve replacement; study completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-17Clinical Trial Update: Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study [Phase 4]
Phase 4 pilot study examining phosphodiesterase type 5 inhibition in aortic stenosis; trial terminated with posted results.
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CLINICAL_TRIALS trial_result · 2019-04-16Clinical Trial Update: The SOLACE-AU Clinical Trial [NA]
Clinical trial update for the SOLACE-AU study (NCT01675596) by Edwards Lifesciences, completed with results posted in 2019, involving severe…
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CLINICAL_TRIALS trial_result · 2019-02-04Clinical Trial Update: First in Human Experience of the St. Jude Medical TAVI Valve and Delivery System [NA]
This update covers the completed first-in-human experience with the St. Jude Medical transcatheter aortic valve and its delivery system.
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CLINICAL_TRIALS withdrawal · 2019-02-04Clinical Trial Update: Assessment of the St. Jude Medical PorticoTM Re-sheathable Aortic Valve System - Alternative Access [NA]
The clinical trial NCT02088021 evaluating the Portico Re-sheathable Aortic Valve System for alternative access in symptomatic aortic stenosi…
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CLINICAL_TRIALS withdrawal · 2019-02-04Clinical Trial Update: Assessment of St Jude Medical Portico Re-sheathable Transapical Aortic Valve System [NA]
A clinical trial evaluating the Portico Re-sheathable Transapical Aortic Valve System sponsored by Abbott has been withdrawn.
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CLINICAL_TRIALS research · 2019-01-30Clinical Trial Update: Biological Collection and Registry of Patients Who Will Have a TAVR (Transcatheter Aortic Valve Replacement) Intervention
This document outlines a biological collection and patient registry for individuals planned to undergo transcatheter aortic valve replacemen…
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: CardioCel Tri-leaflet Repair Study [NA]
A CardioCel Tri-leaflet Repair study by Anteris Technologies completed; the trial assessed outcomes for aortic stenosis and aortic insuffici…
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CLINICAL_TRIALS trial_result · 2019-01-28Clinical Trial Update: EDWARDS INTUITY Valve System CADENCE-MIS Study [NA]
The CADENCE-MIS study evaluating Edwards Lifesciences' INTUITY Valve System has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2018-09-12Clinical Trial Update: Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Study [Phase 4]
A Phase 4 pilot study evaluating phosphodiesterase inhibition with aortic valve replacement in aortic stenosis was terminated; results poste…
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CLINICAL_TRIALS trial_result · 2018-08-29Clinical Trial Update: Self-Centering Guide Catheter Feasibility Study [NA]
A feasibility study on a self-centering guide catheter for aortic stenosis has completed; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-08-23Clinical Trial Update: The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose [NA]
Clinical trial completed evaluating the effect of the hyperinsulinemic normoglycemic clamp on myocardial function and glucose utilization in…