Aortic Stenosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-06-09Clinical Trial Update: AntiCoagulation Versus AcetylSalicylic Acid After Transcatheter Aortic Valve Implantation [Phase 3]
Phase 3 trial comparing AntiCoagulation to AcetylSalicylic Acid after transcatheter aortic valve implantation has completed.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Alternative Peripheral TAVI Accesses
This clinical trial update reports on alternative peripheral access options for transcatheter aortic valve implantation (TAVI); the trial NC…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Transcatheter AortiC Valve Implantation in aorTic stenosIs CardiogenIc Shock [NA]
A clinical trial investigating transcatheter aortic valve implantation in patients with aortic stenosis and cardiogenic shock is currently i…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System [NA]
DurAVR THV System is currently in a recruiting clinical trial to assess safety and effectiveness in patients with severe aortic stenosis and…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Echo-Guided vs Fluoroscopy-Guided Transcatheter Aortic Valve Replacement in Patients With Aortic Stenosis（ECHO-TAVR） [Phase 4]
A Phase 4 trial comparing echo-guided versus fluoroscopy-guided transcatheter aortic valve replacement (TAVR) in patients with aortic stenos…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Randomised Controlled Trial to Establish Whether Dapagliflozin and Spironolactone in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement, Result in Better Left Ventricular Mass Regression, Myocardial Health and Patient Reported Outcomes Than Standard-of-care Therapy Alone. [Phase 2]
This is a Phase 2 randomized trial to test whether adding dapagliflozin and spironolactone to standard care improves left ventricular mass r…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Ischemic And Bleeding Risk Assessment After TAVR
This clinical trial update reports a study assessing ischemic and bleeding risk after transcatheter aortic valve replacement (TAVR) in patie…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: DELINEATE-Prospective
A prospective clinical trial (DELINEATE-Prospective) sponsored by Columbia University is currently recruiting for valvular heart diseases in…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: INFLATE Study: Investigation of the Safety and Performance of a Novel PTV Balloon in Patients Undergoing TAVI for Severe Aortic Stenosis [NA]
The INFLATE study is evaluating the safety and performance of a novel PTV balloon for use in transcatheter aortic valve implantation in pati…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Respiratory and Haemodynamic Effects of Conscious Sedation With Dexmedetomidine for a TAVI Procedure [NA]
A clinical trial update describing the respiratory and hemodynamic effects of conscious sedation with dexmedetomidine during a Transcatheter…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: CLEAR-AS: CT-FFR-Guided Revascularization in Patients With Severe Aortic Stenosis [NA]
The CLEAR-AS study is evaluating CT-FFR-guided revascularization in patients with severe aortic stenosis. The trial is currently in recruitm…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Intravenous Iron Supplement for Iron Deficiency in Patients With Severe Aortic Stenosis [Phase 2]
Phase 2 trial evaluating intravenous iron supplementation for iron deficiency in patients with severe aortic stenosis has completed and resu…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis [Phase 2]
A multicenter Phase 2 trial is evaluating whether lowering lipoprotein(a) with Pelacarsen (TQJ230) can influence the progression of calcific…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Prospective, Multicenter, Observational Study Evaluating Safety and Effectiveness of SAPIEN 3 Transcatheter Aortic Valve Replacement for Type-0 Bicuspid Aortic Valve Stenosis Patients in China
This entry describes a prospective, multicenter observational study evaluating the safety and effectiveness of the SAPIEN 3 transcatheter ao…
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CLINICAL_TRIALS other · 2026-04-14Clinical Trial Update: Valvosoft Outcomes Registry for Real-World Evidence
ClinicalTrials.gov update for the Valvosoft outcomes registry sponsored by Cardiawave SA. The study aims to collect real-world outcomes in s…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation [NA]
This clinical trial update reports on the evaluation of transcatheter aortic valve replacement using the NAVITOR valve in a global study for…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis) [NA]
The STAR trial evaluating transcatheter aortic valve replacement in patients with symptomatic severe native aortic stenosis is currently rec…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Early System Experience With the Abbott Balloon-expandable TAVI System: First-In-Human Study [NA]
This document provides an early-system experience update from Abbott's first-in-human study of the balloon-expandable TAVI System. It concer…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility Study [NA]
This document provides an early feasibility study update on the use of the DurAVR THV System for patients with severe aortic stenosis. The t…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: TRanscatheter Aortic-Valve Implantation With or Without On-site Cardiac Surgery: the TRACS Trial [NA]
The TRACS trial evaluating transcatheter aortic-valve implantation with or without on-site cardiac surgery is currently active but not recru…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: TAVI Without On-Site Cardiac Surgery in Poland: A Randomized Multicenter Trial Protocol [NA]
This document outlines a randomized multicenter trial protocol in Poland to evaluate transcatheter aortic valve implantation (TAVI) without …
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis
An ongoing clinical trial is evaluating transcatheter aortic valve replacement for severe aortic stenosis with low flow, low gradient and is…
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: Safety & Efficacy Study of the Medtronic CoreValve® System-Treatment of Symptomatic Severe Aortic Stenosis With Significant Comorbidities in Extreme Risk Subjects Who Need Aortic Valve Replacement
This update reports on the completed safety and efficacy evaluation of the Medtronic CoreValve System in patients with symptomatic severe ao…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: PRessure-based Evaluation of Disease Improvement in the Course of TAVI
A clinical trial update describes a study evaluating pressure-based assessment of disease improvement during transcatheter aortic valve impl…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Comparative Observational Study of Supra-annular Versus Intra-annular Self-expanding Aortic Valves in Routine Clinical Practice
This observational trial compares supra-annular versus intra-annular self-expanding transcatheter aortic valve devices in routine clinical p…