Clinical Trial Update: A Randomised Controlled Trial to Establish Whether Dapagliflozin and Spironolactone in Patients With Severe Aortic Stenosis Undergoing Aortic Valve Replacement, Result in Better Left Ventricular Mass Regression, Myocardial Health and Patient Reported Outcomes Than Standard-of-care Therapy Alone. [Phase 2]

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Summary

This is a Phase 2 randomized trial to test whether adding dapagliflozin and spironolactone to standard care improves left ventricular mass regression and myocar…

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Diseases / indications

• Aortic Stenosis

Drugs mentioned

• Aldactone (spironolactone)
• FARXIGA (dapagliflozin)

Snippet

Sponsor: University College, London | Conditions: Aortic Stenosis | Phase 2 | Status: NOT_YET_RECRUITING