Antiphospholipid Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Study of the Efficiency of Hydroxychloroquine on the Endothelial Dysfunction and Its Vascular Consequences During the Antiphospholipid Syndrome [Phase 2]
Phase 2 clinical trial evaluating hydroxychloroquine for endothelial dysfunction in antiphospholipid syndrome has been terminated.
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CLINICAL_TRIALS withdrawal · 2026-04-06Clinical Trial Update: HYDROxychloroquine in Syndrome Primary AntiPhospholipid [Phase 2]
A Phase 2 clinical trial of hydroxychloroquine for antiphospholipid syndrome (including pregnancy) has been withdrawn.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Daratumumab in Primary Antiphospholipid Syndrome [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial evaluating daratumumab for primary antiphospholipid syndrome. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Phase 1b Long-term Extension Trial of RAY121 in Immunological Diseases (RAINBOW-LTE Trial) [Phase 1]
Phase 1b long-term extension trial of RAY121 in multiple immunological diseases is currently enrolling by invitation, expanding early-phase …
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CLINICAL_TRIALS other · 2026-04-02Clinical Trial Update: Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial) [Phase 1]
Chugai Pharmaceutical’s RAY121 is being studied in a Phase 1b trial (RAINBOW) across several immunological diseases, and the study is curren…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy [Phase 2]
A Phase 2 study (IMPACT) is evaluating certolizumab pegol to improve pregnancy outcomes in antiphospholipid syndrome during high-risk pregna…
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CLINICAL_TRIALS withdrawal · 2026-03-27Clinical Trial Update: Pregnancy and Medically Assisted Conception in Rare Diseases
Clinical trial NCT02450396 on pregnancy and medically assisted conception in rare autoimmune diseases has been withdrawn.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: An Exploratory Clinical Study of YTS109 Cell for R/R Autoimmune Diseases [Phase 1]
Exploratory Phase 1 clinical trial evaluating YTS109 Cell for relapsed/refractory autoimmune diseases, including systemic lupus erythematosu…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: Exploratory Clinical Study on YTS109 Cell Therapy for Autoimmune Diseases [Phase 1]
A Phase 1 exploratory study evaluating the safety and feasibility of YTS109 cell therapy for multiple autoimmune diseases, currently recruit…
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases [Phase 1]
Phase 1 trial update on YTS109 cell therapy for relapsed/refractory autoimmune diseases, currently recruiting across multiple indications.
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CLINICAL_TRIALS withdrawal · 2026-03-02Clinical Trial Update: A Study to Evaluate Crovalimab in People With Antiphospholipid Syndrome (APS) [Phase 2]
A Phase 2 study evaluating crovalimab for antiphospholipid syndrome has been withdrawn.
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CLINICAL_TRIALS research · 2026-03-02Clinical Trial Update: A Clinical Study of YTS109 Cell for R/R Autoimmune Diseases [Phase 1]
Phase 1 clinical study of YTS109 cell therapy for refractory autoimmune diseases is currently recruiting. The trial will evaluate safety and…
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: YTS109 in Pediatric Relapsed/Refractory Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial evaluating YTS109 in pediatric relapsed/refractory autoimmune diseases, including SLE and diffuse systemic sclerosi…
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CLINICAL_TRIALS research · 2026-01-30Clinical Trial Update: Observational Study to Evaluate the Effectiveness of DOACS for Secondary Thrombosis Prevention in Low-risk Thrombotic APS Patients
An observational study is evaluating the effectiveness of direct oral anticoagulants for secondary thrombosis prevention in low-risk antipho…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Medium-term Follow-up of Patients With Obstetric Antiphospholipid Syndrome: MRI Study of White Matter [NA]
This clinical trial update reports medium-term follow-up findings from patients with obstetric antiphospholipid syndrome. The study uses MRI…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: Effect of Telitacicept on Antibody Titers in Primary APS Patients [Phase 2]
A Phase 2 trial evaluating the effect of Telitacicept on antibody titers in patients with primary antiphospholipid syndrome has completed.
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Anti-CD19 IL-10/IL15 CAR-NK Cells in Refractory/Relapsed Autoimmune Diseases [NA]
This clinical trial is recruiting to evaluate anti-CD19 IL-10/IL-15 CAR-NK cells for refractory/relapsed autoimmune diseases. Conditions inc…
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CLINICAL_TRIALS other · 2025-12-24Clinical Trial Update: Clinical Study of BCT301 Cell Injection Therapy for Refractory Autoimmune Diseases [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating BCT301 cell injection therapy for refractory autoimmune diseases, including systemic lupus erythe…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: A Study of CD19 UCAR-T Cells in Subjects With Autoimmune Diseases [NA]
A clinical trial update evaluating CD19 UCAR-T cell therapy in autoimmune diseases; the study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Registry on Augmented Antithrombotic Treatment Regimens for Patients With Arterial Thrombotic APS
This registry from McMaster University aims to evaluate augmented antithrombotic treatment regimens for patients with antiphospholipid syndr…
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Register for Pediatric Patients With Antiphospholipid Syndrome (APS): European Project Extended Internationally Study
A pediatric antiphospholipid syndrome trial (NCT00616317) sponsored by the University of California, Davis is currently recruiting internati…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Obstetric Antiphospholipid Antibody Syndrome : Contribution of the Evaluation of ADAMTS13 Made at the Diagnosis of Pregnancy on Evaluation the Risk of Pre-eclampsia
A completed obstetric trial evaluating whether ADAMTS13 measurement at diagnosis of pregnancy in women with antiphospholipid antibody syndro…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Characterization of Autoreactive b Lymphocytes in Autoimmune Diseases and Immune Deficiencies
This clinical trial aims to characterize autoreactive B lymphocytes in autoimmune diseases and immune deficiencies. The study status is not …
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Evaluation of the Incidence of Cancer in the Follow-up of Women With 3 Consecutive Embryonic Demises Before 10 Weeks or 1 Fetal Death, According to Their Thrombophilia Status, With a Special Focus on Women With an Obstetric Antiphospholipid Symdrome (oAPS)
A completed clinical study evaluating cancer incidence during follow-up of women with a history of three consecutive embryonic losses before…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Prevalence and Consequences of Antiphospholipid Syndrome in Patients Aged 65 and Over With Ischemic Strokes (IS) [NA]
This clinical trial update indicates ongoing recruitment for a study examining the prevalence and consequences of antiphospholipid syndrome …