Antiphospholipid Syndrome
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Assessment of the Prevalence of Major Psychiatric Disorders in a Cohort of Women With Clinical Criteria Corresponding to Pure, Abortive-form, Obstetrical, Antiphospholipid Syndrome
The study evaluates the prevalence of major psychiatric disorders in women who meet clinical criteria for antiphospholipid syndrome and rela…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: The Prognostic Value of PGF and sFlt1 Variations Induced by the First Low-molecular-weight-heparin Injections in Women With Obstetrical Antiphospholipids Antibody Syndrome Starting a New Pregnancy and Following Treatment in Accordance With International Recommendations
A completed clinical trial studied the prognostic value of PGF and sFlt1 biomarker variations induced by initial low-molecular-weight hepari…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE)
A completed clinical trial registry entry for patients with antiphospholipid syndrome and/or systemic lupus erythematosus, sponsored by Assi…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: Evaluation of Cell Membrane Expression of Annexin A2 on Monocytes by Flow Cytometry in Primary Antiphospholipid Syndrome [NA]
This clinical trial update describes an ongoing study evaluating the expression of Annexin A2 on monocytes in primary antiphospholipid syndr…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Follow-up Cohort of Patients With Antiphospholipid Syndrome
This clinical trial update describes a follow-up cohort study in Antiphospholipid Syndrome, with participant recruitment ongoing.
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Hematological Markers MPV, PLR, and NLR in Primary Versus Secondary Antiphospholipid Syndrome
A clinical trial update investigating whether hematological markers MPV, PLR, and NLR differ between primary and secondary antiphospholipid …
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study evaluating universal CD19-targeting CAR-γδT cells for refractory autoimmune diseases,…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Pilot Study of Gut Commensals in Antiphospholipid Syndrome
A pilot study evaluates gut commensal bacteria in antiphospholipid syndrome; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Hematological Disorders in EHPVO Patients
A clinical trial update describes a study on hematological disorders in patients with Extrahepatic portal vein obstruction and thrombophilia…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Anti-CD38 Antibody Treating APS With Thrombocytopenia [Phase 2]
A Phase 2 clinical trial evaluating an anti-CD38 antibody for antiphospholipid syndrome with thrombocytopenia is currently recruiting in Chi…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: A Clinical Study of YTS109 Cell in R/R Autoimmune Diseases [Phase 1]
A Phase 1 clinical trial evaluating YTS109 cell therapy for relapsed/refractory autoimmune diseases is currently recruiting. The study cover…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Sirolimus Monotherapy in the Treatment of Antiphospholipid Antibody Related Thrombocytopenia [Phase 4]
A Phase 4 clinical trial is evaluating sirolimus as a monotherapy for antiphospholipid antibody-related thrombocytopenia. The study is curre…
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Prevalence and Etiologies of Intracranial Stenosis in Patients With Antiphospholipid Syndrome
A clinical trial from The Chinese University of Hong Kong investigating the prevalence and etiologies of intracranial arterial stenosis in p…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: DOAC Versus VKA in Patients With Non-high-risk APS : Prospective Cohort Study
This clinical trial update describes a prospective cohort study comparing direct oral anticoagulants (DOACs) to vitamin K antagonists (VKAs)…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Telitacicept in Primary APS Patients [Phase 2]
Phase 2 trial of telitacicept in primary antiphospholipid syndrome has been terminated.
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Negative Antiphospholipid Syndrome: a Multicentric Study
This multicenter clinical trial is recruiting to investigate management of Antiphospholipid Syndrome, including Seronegative Antiphospholipi…
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CLINICAL_TRIALS research · 2025-04-20Clinical Trial Update: OBServaToIre interNational Des Patients AnTiphospholipidEs traités Par Anticoagulants Oraux Directs
An international observational study at Central Hospital, Nancy, France, evaluating antiphospholipid syndrome patients treated with direct o…
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CLINICAL_TRIALS other · 2025-04-13Clinical Trial Update: Predictors of Pregnancy Outcome in Systemic Lupus Erythematosus (SLE) and Antiphospholipid Syndrome (APS)
This clinical trial update indicates that a study on predictors of pregnancy outcomes in systemic lupus erythematosus and antiphospholipid s…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases
This entry describes the Armenian nationwide registry of systemic autoimmune and autoinflammatory diseases, which is currently recruiting pa…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases [Phase 2]
Phase 2 clinical trial update on BCMA-CD19 CAR-T therapy for refractory autoimmune diseases, currently recruiting. The study targets several…
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CLINICAL_TRIALS research · 2025-03-19Clinical Trial Update: Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome
This clinical trial update describes an ongoing Duke University study investigating genetic risk factors associated with Antiphospholipid Sy…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Safety and Efficacy of Zanubrutinib in the Treatment of Antiphospholipid Syndrome With Secondary Thrombocytopenia [Phase 2]
A Phase 2 clinical trial is evaluating the safety and efficacy of zanubrutinib for antiphospholipid syndrome with secondary thrombocytopenia…
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CLINICAL_TRIALS other · 2025-02-05Clinical Trial Update: Clinical Outcomes of Primary Versus Secondary Antiphospholipid Syndrome
Clinical trial comparing outcomes of primary versus secondary antiphospholipid syndrome; currently not recruiting.
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: Effect of Belimumab on Antibody Titers in Primary APS Patients [Phase 2]
A Phase 2 clinical trial is evaluating belimumab for reducing antibody titers in primary antiphospholipid syndrome; the study is currently r…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune Diseases [NA]
A clinical trial update shows BRL-301 universal CAR-T cells from Bioray Laboratories enrolling (by invitation) for relapse or refractory aut…