Anaplastic Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma [Phase 1]
Phase 1 trial evaluating high-dose vorinostat with fractionated SBRT in patients with recurrent glioma; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2014-11-14Clinical Trial Update: Interstitial Infusion of IL13-PE38QQR Cytotoxin in Recurrent Malignant Glioma [Phase 1, Phase 2]
The clinical trial evaluating interstitial infusion of IL13-PE38QQR cytotoxin in recurrent malignant glioma has completed Phase 1 and Phase …
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CLINICAL_TRIALS trial_result · 2014-11-04Clinical Trial Update: Sorafenib in Newly Diagnosed High Grade Glioma [Phase 1]
Phase 1 trial update evaluating sorafenib in newly diagnosed high-grade glioma, including glioblastoma, gliosarcoma, and various anaplastic …
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CLINICAL_TRIALS trial_result · 2014-08-22Clinical Trial Update: Efficacy and Safety of AP 12009 in Patients With Recurrent or Refractory Anaplastic Astrocytoma or Secondary Glioblastoma [Phase 3]
A Phase 3 study of AP-12009 in recurrent or refractory anaplastic astrocytoma or secondary glioblastoma was terminated, and results have bee…
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CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: BIBF 1120 for Recurrent High-Grade Gliomas [Phase 2]
Phase 2 trial update on BIBF 1120 (nintedanib) for recurrent high-grade gliomas, with the study status now completed and results posted in 2…
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Aflibercept, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed or Recurrent Glioblastoma Multiforme, Gliosarcoma, or Other Malignant Glioma [Phase 1]
Phase 1 clinical trial assessing aflibercept in combination with radiation therapy and temozolomide in adults with newly diagnosed or recurr…
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CLINICAL_TRIALS trial_result · 2014-05-30Clinical Trial Update: Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1]
This update covers a Phase 1 trial of sorafenib in patients with recurrent or progressive malignant glioma, including several glioma subtype…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: Cilengitide in Treating Younger Patients With Recurrent or Progressive High-Grade Glioma That Has Not Responded to Standard Therapy [Phase 2]
This Phase 2, NCI-sponsored trial evaluated cilengitide in children and adolescents with recurrent or progressive high-grade glioma refracto…
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, Intracranial Glioblastoma, Gliosarcoma or Anaplastic Astrocytoma [Phase 1]
Phase 1 study evaluating the safety and potential activity of bevacizumab plus cediranib in patients with metastatic or unresectable solid t…
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CLINICAL_TRIALS trial_result · 2013-12-03Clinical Trial Update: Phase IIb Clinical Trial With TGF-β2 Antisense Compound AP 12009 for Recurrent or Refractory High-grade Glioma [Phase 2]
A Phase IIb trial of AP-12009, a TGF-β2 antisense oligonucleotide, for recurrent or refractory high-grade glioma including glioblastoma and …
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CLINICAL_TRIALS trial_result · 2013-10-25Clinical Trial Update: Ph I Oral Topotecan and Temozolomide for Patients With Malignant Gliomas [Phase 1]
This is a completed Phase I trial evaluating an oral combination of topotecan and temozolomide for malignant gliomas, including glioblastoma…
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CLINICAL_TRIALS trial_result · 2013-06-14Clinical Trial Update: Bevacizumab in Reducing CNS Side Effects in Patients Who Have Undergone Radiation Therapy to the Brain for Primary Brain Tumor, Meningioma, or Head and Neck Cancer [Phase 2]
Phase 2 trial evaluating bevacizumab to reduce central nervous system side effects after brain radiotherapy in patients with various brain t…
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CLINICAL_TRIALS trial_result · 2013-06-10Clinical Trial Update: Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma [Phase 2]
A Phase 2 clinical trial evaluating ritonavir and lopinavir for progressive or recurrent high-grade glioma was terminated, with results post…
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CLINICAL_TRIALS trial_result · 2013-02-20Clinical Trial Update: PH I Addition of Farnesyl Transferase Inhibitor to Temozolomide for Pts w Gr 3 & 4 Malignant Gliomas [Phase 1]
A Phase I trial evaluated adding a Farnesyl Transferase Inhibitor to temozolomide in patients with Grade 3-4 malignant gliomas, and the stud…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: Bortezomib in Treating Patients With Recurrent Glioma [Phase 1]
Phase 1 trial evaluating bortezomib in adults with recurrent glioma; the study has been terminated.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Erlotinib in Treating Patients With Solid Tumors and Liver or Kidney Dysfunction [Phase 1]
Phase 1 clinical trial evaluating erlotinib in patients with solid tumors and liver or kidney dysfunction has been completed.
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CLINICAL_TRIALS trial_result · 2013-01-16Clinical Trial Update: Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors [Phase 1]
This document is a terminated Phase 1 trial update evaluating PET imaging with 18F-EF5 to measure oxygenation in brain tumor cells of adults…
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CLINICAL_TRIALS trial_result · 2012-11-30Clinical Trial Update: Tumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma [NA]
This completed clinical trial update reports on tumor DNA and MRI/CT imaging findings in patients with grade III or grade IV malignant gliom…
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CLINICAL_TRIALS trial_result · 2012-11-16Clinical Trial Update: Phase IIa Safety and Light Dose-escalation Study in Patients With Primary or Recurrent/High-grade Glioma Using the Litx™ System to Confirm the Zone of Tumor Destruction During the Intraoperative Treatment of Glioma [Phase 2]
Phase IIa safety and light-dose escalation trial in patients with primary or recurrent high-grade glioma using the Litx System to define the…
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CLINICAL_TRIALS trial_result · 2012-10-31Clinical Trial Update: A Phase II Trial of Sutent (Sunitinib; SU011248) for Recurrent Anaplastic Astrocytoma and Glioblastoma [Phase 2]
A Phase II trial evaluated sunitinib (Sutent) for recurrent anaplastic astrocytoma and glioblastoma. The results were posted in October 2012…
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CLINICAL_TRIALS trial_result · 2012-09-13Clinical Trial Update: Leflunomide in Treating Patients With Anaplastic Astrocytoma in First Relapse [Phase 2]
Pfizer-sponsored Phase 2 trial evaluating Leflunomide in patients with first-relapse anaplastic astrocytoma has completed.
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CLINICAL_TRIALS trial_result · 2012-08-31Clinical Trial Update: Tandutinib Plus Bevacizumab to Treat Recurrent Brain Tumors [Phase 2]
A Phase 2 trial evaluated tandutinib in combination with bevacizumab for recurrent brain tumors, with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-08-29Clinical Trial Update: Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy [Phase 1]
A Phase 1 trial evaluating chemotherapy and radiation with chemoprotective cells and an experimental drug to reduce chemotherapy resistance …
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CLINICAL_TRIALS trial_result · 2012-08-03Clinical Trial Update: Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Newly Diagnosed Malignant Glioma [Phase 3]
Phase 3 clinical trial evaluating intracranially implanted carmustine for newly diagnosed malignant glioma, assessing safety and efficacy. T…
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Recurrent Malignant Glioma [NA]
A clinical trial update describes a safety and efficacy study of intracranially implanted Carmustine for recurrent malignant glioma, with th…