Anaplastic Astrocytoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-12-16Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Anaplastic Astrocytoma [Phase 2]
Phase 2 clinical trial results for antineoplaston therapy in patients with anaplastic astrocytoma, sponsored by the Burzynski Research Insti…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: The Effect of Radiotherapy and Temozolomide on the Tumor Vasculature and Stem Cells in Human High-grade Astrocytomas
The clinical trial evaluating the effects of radiotherapy and temozolomide on tumor vasculature and cancer stem cells in high-grade astrocyt…
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CLINICAL_TRIALS trial_result · 2016-11-15Clinical Trial Update: FR901228 in Treating Patients With Recurrent High-Grade Gliomas [Phase 1, Phase 2]
A completed Phase 1/2 clinical trial evaluated FR901228 in adults with recurrent high-grade gliomas; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-10-04Clinical Trial Update: Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating an NY-ESO-1 vaccine therapy with or without sirolimus in patients whose tumors express NY-ESO-1.
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CLINICAL_TRIALS trial_result · 2016-07-14Clinical Trial Update: Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Anaplastic Astrocytoma [Phase 2]
A Phase 2 clinical trial update evaluating the combination of chemotherapy and radiation therapy for patients with anaplastic astrocytoma.
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CLINICAL_TRIALS trial_result · 2016-05-30Clinical Trial Update: Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery [Phase 1]
This clinical trial update reports on a Phase 1 study of the oncolytic herpes simplex virus HSV-1716 in children with refractory or recurren…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Cellular Immunotherapy Study for Brain Cancer [Phase 1]
Phase 1 clinical trial update describes completion of a cellular immunotherapy study for brain tumors to assess safety and initial signals o…
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CLINICAL_TRIALS trial_result · 2016-04-27Clinical Trial Update: Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Astrocytoma [Phase 1]
Phase 1 trial evaluating temozolomide with radiation therapy for newly diagnosed glioblastoma and anaplastic astrocytoma; results have been …
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CLINICAL_TRIALS trial_result · 2016-04-18Clinical Trial Update: Temsirolimus and Perifosine in Treating Patients With Recurrent or Progressive Malignant Glioma [Phase 1, Phase 2]
Clinical trial update for Temsirolimus and Perifosine in recurrent or progressive malignant glioma (Phase 1/2) with completed status and pos…
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CLINICAL_TRIALS trial_result · 2016-04-15Clinical Trial Update: AMG 595 First-in-Human in Recurrent Gliomas [Phase 1]
Amgen completed a first-in-human Phase 1 trial of AMG 595 in recurrent gliomas to assess safety and early signals of activity. The study inc…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: A Randomized Phase II Trial of Vandetanib (ZD6474) in Combination With Carboplatin Versus Carboplatin Alone Followed by Vandetanib Alone in Adults With Recurrent High-Grade Gliomas [Phase 2]
Results from a Phase II randomized trial in adults with recurrent high-grade gliomas comparing vandetanib with carboplatin followed by vande…
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CLINICAL_TRIALS trial_result · 2016-03-07Clinical Trial Update: AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors [Phase 1]
Phase 1 study of AZD2171 (cediranib) in children with recurrent, progressive, or refractory primary central nervous system tumors has comple…
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CLINICAL_TRIALS trial_result · 2016-02-29Clinical Trial Update: Sunitinib in Treating Patients With Recurrent Malignant Gliomas [Phase 2]
Phase 2 trial evaluating sunitinib for adults with recurrent malignant gliomas has completed; results were posted in 2016.
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Oral Tarceva Study for Recurrent/Residual Glioblastoma Multiforme and Anaplastic Astrocytoma [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial of Tarceva (erlotinib) for recurrent/residual glioblastoma multiforme and anaplastic astr…
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CLINICAL_TRIALS trial_result · 2015-10-02Clinical Trial Update: VEGF Trap in Treating Patients With Recurrent Malignant Gliomas That Did Not Respond to Temozolomide [Phase 2]
Phase 2 trial evaluating aflibercept (VEGF Trap) for recurrent malignant gliomas unresponsive to temozolomide has completed; results were po…
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CLINICAL_TRIALS trial_result · 2015-09-29Clinical Trial Update: RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma [Phase 1]
This Phase 1 trial assessed RO4929097 in combination with temozolomide and radiation therapy for newly diagnosed malignant glioma and has co…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma [Phase 1, Phase 2]
Phase 1/2 trial evaluating RO4929097 in combination with Bevacizumab for progressive or recurrent malignant glioma was terminated; results w…
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CLINICAL_TRIALS trial_result · 2015-06-15Clinical Trial Update: Erlotinib and Temsirolimus in Treating Patients With Recurrent Malignant Glioma [Phase 1, Phase 2]
This entry reports the completion and posted results of a Phase 1/2 trial evaluating erlotinib in combination with temsirolimus for recurren…
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CLINICAL_TRIALS trial_result · 2015-06-12Clinical Trial Update: A Study of PD 0332991 in Patients With Recurrent Rb Positive Glioblastoma [Phase 2]
A Phase 2 study of Palbociclib (PD-0332991) in recurrent RB-positive glioblastoma was terminated. Results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Phase II NKTR-102 In Bevacizumab-Resistant High Grade Glioma [Phase 2]
A Phase II trial of NKTR-102 in bevacizumab-resistant high-grade glioma has completed, with results posted in 2015, evaluating activity in a…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2 [Phase 1]
Phase I trial evaluating intratumoral GRm13Z40-2 T-cell therapy (genetically modified allogeneic CD8+ T cells expressing IL-13-Zetakine and …
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CLINICAL_TRIALS trial_result · 2015-04-22Clinical Trial Update: Super-Selective Intraarterial Intracranial Infusion of Avastin (Bevacizumab) [Phase 1]
Completed Phase 1 study evaluating super-selective intraarterial intracranial infusion of bevacizumab (Avastin) for glioblastoma and anaplas…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms [Phase 2]
A Phase II trial of Carmustine, Streptozocin, and Mercaptopurine for refractory or recurrent brain neoplasms has completed.
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CLINICAL_TRIALS trial_result · 2015-01-07Clinical Trial Update: A Phase I Trial of Nanoliposomal CPT-11 (NL CPT-11) in Patients With Recurrent High-Grade Gliomas [Phase 1]
This report covers a Phase I trial of nanoliposomal irinotecan (NL-CPT-11) in patients with recurrent high-grade gliomas, completed to evalu…
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumors [Phase 1]
This Phase 1 trial evaluated the combination of RO4929097, a gamma-secretase inhibitor, with Cediranib maleate in adults with advanced solid…