Amyloidosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-12-24Clinical Trial Update: Renal AL Amyloid Involvement and NEOD001 [Phase 2]
Phase 2 trial evaluating NEOD001 for renal AL amyloidosis was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-10-16Clinical Trial Update: Multiple Treatment Session Study to Assess GSK2398852 Administered Following and Along With GSK2315698 [Phase 2]
Phase 2 trial update for a study evaluating GSK2398852 with GSK2315698 in amyloidosis has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-09-23Clinical Trial Update: A Safety Study of GSK3039294 in Healthy Volunteers and Patients With Systemic Amyloidosis [Phase 1]
Phase 1 safety study of GSK3039294 in healthy volunteers and amyoidosis patients, terminated with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: Biodistribution of 89Zirconium-labelled GSK2398852 Using PET Imaging [Phase 1]
Phase 1 biodistribution study of 89Zirconium-labelled GSK2398852 using PET imaging in amyloidosis; study TERMINATED with results posted.
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy [Phase 2, Phase 3]
Phase 2/3 trial results summarize efficacy and safety of inotersen for familial amyloid polyneuropathy (FAP).
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Phase 1/2, Open Label, Dose Escalation Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis [Phase 1, Phase 2]
Phase 1/2 open-label dose-escalation trial of NEOD001 in subjects with light chain (AL) amyloidosis completed.
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis [Phase 1]
This is a completed Phase 1 study evaluating the safety of GSK2398852 when co-administered with GSK2315698 in patients with systemic amyloid…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Vinorelbine and Gemcitabine in Myeloma [Phase 2]
A Phase 2 clinical trial evaluating vinorelbine and gemcitabine in patients with multiple myeloma (and amyloidosis) has completed.
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: SAP Depleter Dose Escalation Study in Healthy Volunteers [Phase 1]
Phase 1 dose-escalation study of a SAP depleter in healthy volunteers; the trial has completed.
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CLINICAL_TRIALS trial_result · 2017-06-09Clinical Trial Update: SAP Depleter Dose Assessment Study in Patients [Phase 1]
A Phase 1 dose assessment study of an SAP depleter in patients with amyloidosis has completed.
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CLINICAL_TRIALS trial_result · 2017-06-06Clinical Trial Update: Safety and Effect of Doxycycline in Patients With Amyloidosis [Phase 2]
A Phase 2 clinical trial assessed the safety and potential effect of doxycycline in patients with amyloidosis; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-10Clinical Trial Update: Idelalisib for Immunoglobulin M (IgM)-Associated Primary (AL) Amyloidosis [Phase 2]
Phase 2 trial is terminated for idelalisib in IgM-associated primary (AL) amyloidosis; results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-06Clinical Trial Update: Bortezomib and Dexamethasone Followed by High-Dose Melphalan and Stem Cell Transplantation for Primary (AL) Amyloidosis [Phase 2]
Phase 2 trial evaluating a conditioning regimen of bortezomib and dexamethasone followed by high-dose melphalan and stem cell transplantatio…
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: Phase 1 Study of GSK2315698 in Healthy Japanese Subjects [Phase 1]
A Phase 1 study of GSK2315698 in healthy Japanese subjects has completed; amyloidosis is listed as the associated condition.
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CLINICAL_TRIALS trial_result · 2015-11-17Clinical Trial Update: B-Receptor Signaling in Cardiomyopathy
This clinical trial update announces the completion of a study examining B-Receptor signaling in cardiomyopathy.
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CLINICAL_TRIALS trial_result · 2015-04-03Clinical Trial Update: S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS.
A SWOG trial (NCT00919139) evaluating a blood/bone marrow repository from patients with multiple myeloma, smoldering myeloma, Waldenström's …
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CLINICAL_TRIALS trial_result · 2014-06-05Clinical Trial Update: CC-4047 and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Amyloidosis [Phase 2]
Phase 2 trial evaluating pomalidomide (CC-4047) plus dexamethasone in relapsed or refractory multiple myeloma and amyloidosis; results have …
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CLINICAL_TRIALS trial_result · 2010-10-01Clinical Trial Update: High-Dose Melphalan Followed by Peripheral Stem Cell Transplant in Treating Patients With Amyloidosis [Phase 2]
Phase 2 clinical trial evaluating high-dose melphalan followed by peripheral stem cell transplantation in patients with amyloidosis. The stu…
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CLINICAL_TRIALS trial_result · 2010-09-14Clinical Trial Update: Autologous Stem Cell Rescue for Primary Amyloidosis [Phase 2]
Phase 2 clinical trial evaluating autologous stem cell rescue for primary amyloidosis has completed.
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CLINICAL_TRIALS trial_result · 2007-04-04Clinical Trial Update: Characteristics of Patients With Amyloidosis & Heart Failure Being Evaluated for a Heart Transplant
A completed clinical trial update describes characteristics of patients with amyloidosis-related cardiomyopathy and heart failure who were e…