Amyloidosis
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Hereditary Transthyretin Amyloidosis Polyneuropathy in Patients With Carpal Tunnel Syndrome in Russia
This document reports the completion of a clinical trial investigating hereditary transthyretin amyloidosis with polyneuropathy in patients …
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Diagnostic Utility of F-18 Florbetapir PET/MR in Peripheral Nerve Amyloidosis [Phase 1, Phase 2]
A completed Phase 1/Phase 2 study evaluating the diagnostic utility of the PET tracer F-18 Florbetapir in conjunction with MRI for periphera…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
Completed clinical trial update describing approaches to monitoring early disease progression in hereditary transthyretin amyloidosis. The s…
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis [Phase 1, Phase 2]
A Phase 1/2a clinical trial is investigating belantamab mafodotin for relapsed or refractory AL amyloidosis; the study is currently recruiti…
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CLINICAL_TRIALS trial_result · 2026-02-11Clinical Trial Update: Study of Olfactory Disorders in Patients With Cardiac Amyloidosis [NA]
A completed clinical trial conducted by Assistance Publique - Hôpitaux de Paris studied olfactory disorders in patients with cardiac amyloid…
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma [Phase 2]
A Phase 2 clinical trial is evaluating daratumumab after stem cell transplant in patients with multiple myeloma. The study is currently acti…
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CLINICAL_TRIALS trial_result · 2025-03-12Clinical Trial Update: Ixazomib Rollover Study [Phase 2]
A Phase 2 Ixazomib rollover study has completed, with results posted on 2025-03-12. The study encompassed multiple myeloma, lymphoma, and am…
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Screening for Amyloidosis Before Aortic Valve Elective Replacement
Charite University in Berlin is screening for amyloidosis in patients undergoing elective aortic valve replacement; the trial (NCT04869631) …
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: carDIo-ttranSSfOrm nucLEar Imaging Study
The carDIo-ttranSSfOrm nucLEar Imaging Study, sponsored by Oregon Health and Science University, has been terminated. The study involves amy…
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: Dietary Reporting in the Amyloidoses [NA]
This clinical trial update reports a recruiting study sponsored by the Barbara Ann Karmanos Cancer Institute investigating dietary reporting…
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CLINICAL_TRIALS trial_result · 2024-11-06Clinical Trial Update: MargheRITA (Remote Intelligence for Therapeutic Adherence) [NA]
A completed clinical trial named MargheRITA (Remote Intelligence for Therapeutic Adherence) sponsored by Advice Pharma Group srl studied tre…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Single Dose Study to Evaluate the Pharmacokinetics of Acoramidis Modified Release Formulations in Healthy Subjects [Phase 1]
Phase 1 pharmacokinetic study evaluating acoramidis modified-release formulations in healthy subjects has been completed.
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CLINICAL_TRIALS trial_result · 2024-04-17Clinical Trial Update: Frontline Lenalidomide for AL Amyloidosis Involving Myocardium [Phase 3]
Phase 3 trial evaluating frontline lenalidomide for amyloidosis involving the heart has completed.
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CLINICAL_TRIALS trial_result · 2023-12-06Clinical Trial Update: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran) [Phase 3]
Phase 3 trial update for patisiran in patients with transthyretin-mediated amyloidosis who have already been treated with patisiran; study c…
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CLINICAL_TRIALS trial_result · 2023-10-25Clinical Trial Update: APG-2575 in Combination With Novel Therapeutic Regimens in Subjects With Relapsed or Refractory Multiple Myeloma [Phase 1, Phase 2]
Phase 1/2 trial evaluating APG-2575 in combination regimens for relapsed or refractory multiple myeloma and amyloidosis.
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: A Study to Desensitize Allergic Reactions to Treatments for Blood Disorders [Phase 2]
Phase 2 clinical trial update on desensitization for allergic reactions to treatments used for blood disorders, completed.
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis Patients [Phase 2]
A Phase 2 clinical trial evaluating propylene glycol-free melphalan hydrochloride (Evomela) in systemic amyloidosis (AL type) has been termi…
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CLINICAL_TRIALS trial_result · 2023-01-25Clinical Trial Update: Lenalidomide, Dexamethasone, and Elotuzumab With or Without Cyclophosphamide in Treating Patients With Relapsed Primary Amyloidosis [Phase 2]
Phase 2 clinical trial evaluating lenalidomide, dexamethasone, and elotuzumab with or without cyclophosphamide in relapsed primary amyloidos…
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CLINICAL_TRIALS trial_result · 2022-12-13Clinical Trial Update: Combined Bone Marrow and Renal Transplantation for Hematologic Disorders With End Stage Renal Disease [NA]
A completed clinical trial investigating combined bone marrow and renal transplantation for hematologic disorders in patients with end-stage…
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CLINICAL_TRIALS trial_result · 2021-07-09Clinical Trial Update: Daratumumab Therapy for Patients With Refractory or Relapsed AL Amyloidosis [Phase 2]
Phase 2 trial evaluating daratumumab therapy in patients with refractory or relapsed amyloidosis has been completed.
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CLINICAL_TRIALS trial_result · 2021-04-30Clinical Trial Update: Lenalidomide, Dexamethasone and Cyclophosphamide in Amyloidosis (AL) [Phase 1, Phase 2]
Phase 1/2 clinical trial of lenalidomide, dexamethasone, and cyclophosphamide in amyloidosis (AL) completed.
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CLINICAL_TRIALS trial_result · 2021-04-15Clinical Trial Update: A Dose Escalation Study of Carfilzomib Taken With Thalidomide and Dexamethasone in Relapsed AL Amyloidosis [Phase 1, Phase 2]
A dose-escalation study of carfilzomib with thalidomide and dexamethasone in relapsed AL amyloidosis has completed Phase 1/2, with results p…
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CLINICAL_TRIALS trial_result · 2020-12-04Clinical Trial Update: Doxycycline and TUDCA in Patients With Transthyretin Amyloid Cardiomyopathy [Phase 1, Phase 2]
Phase 1/2 trial investigating doxycycline and TUDCA in transthyretin amyloid cardiomyopathy has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-30Clinical Trial Update: Bortezomib/Dexamethasone (BD), Followed By Autologous Stem Cell Transplantation and Maintenance Bortezomib/Dexamethasone For the Initial Treatment of Monoclonal Immunoglobulin Deposition Disease (MIDD) Associated With Multiple Myeloma and AL Amyloidosis [NA]
Clinical trial update on BD followed by autologous stem cell transplant and maintenance BD for initial treatment of Monoclonal Immunoglobuli…
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Trial of Two Stem Cell Doses To Reduce Transplant Induced Symptom Burden [Phase 2]
Phase 2 trial evaluating two stem cell dose regimens to reduce transplant-induced symptom burden in patients with multiple myeloma or primar…