Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-02-06Clinical Trial Update: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase [Phase 2]
Phase 2 study evaluating safety, tolerability, and potential efficacy markers for CHF 5074 in mild cognitive impairment and Alzheimer's dise…
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CLINICAL_TRIALS research · 2014-02-06Clinical Trial Update: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Open Label Extension (CT04 OLEP) [Phase 2]
Open-label Phase 2 extension evaluating the safety and tolerability of multiple-dose regimens of CHF 5074 and exploring potential markers of…
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FDA approval · 2014-02-05FDA Approved: FLUDEOXYGLUCOSE F 18 — Original Application (Washington University School of Medicine)
FDA approves the original application for Fludeoxyglucose F-18 (FDG F-18), a radiopharmaceutical used in PET imaging to localize abnormal me…
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CLINICAL_TRIALS trial_result · 2014-02-05Clinical Trial Update: Safety, Radiation Dosimetry, Biokinetics, and Effectiveness of [18F]MK3328 (MK-3328-001) [Phase 1]
Phase 1 clinical trial update for the PET radiotracer MK-3328 ([18F]MK3328) assessing safety, radiation dosimetry, biokinetics, and effectiv…
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CLINICAL_TRIALS research · 2014-01-31Clinical Trial Update: Measurement of Retinal Nerve Fiber Layer Thickness - a Biomarker for the Early Detection of Alzheimer's Disease?
This clinical trial update investigates retinal nerve fiber layer thickness as a biomarker for the early detection of Alzheimer's disease. N…
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CLINICAL_TRIALS trial_result · 2014-01-29Clinical Trial Update: A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease [Phase 3]
Phase 3 randomized trial evaluated the combination of memantine and vitamin E for Alzheimer's disease. Results from the study have been post…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Effect of Repetitive Transcranial Magnetic Stimulation on Language in Alzheimer's Disease [Phase 2]
Phase 2 trial results assess whether repetitive transcranial magnetic stimulation improves language in Alzheimer's disease. The study, spons…
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: Phase II Study of Florbetaben (BAY94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid. [Phase 2]
Phase II trial evaluating Florbetaben PET imaging (BAY94-9172) for detection/exclusion of cerebral beta-amyloid; study completed with result…
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CLINICAL_TRIALS trial_result · 2014-01-24Clinical Trial Update: Nutritional Programme for Dementia Elderly Patient [NA]
Nestlé-sponsored clinical trial evaluating a nutritional programme for elderly patients with Alzheimer's disease and dementia has completed.…
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FDA approval · 2014-01-22FDA Approved: DONEPEZIL HYDROCHLORIDE — Original Application (Macleods Pharmaceuticals Limited)
FDA approved a generic version of donepezil hydrochloride (ANDA 202631) from Macleods Pharmaceuticals Limited.
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CLINICAL_TRIALS trial_result · 2014-01-22Clinical Trial Update: The Detection of Early Dementia With the Digital Game Memory
A completed clinical trial evaluated a digital game called Memory for detecting early dementia in Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2014-01-13Clinical Trial Update: Safety, Tolerability, Pharmacokinetics of EVP-0962 and Effects of EVP-0962 on Cerebral Spinal Fluid Amyloid Concentrations in Healthy Subjects and in Subjects With Mild Cognitive Impairment or Early Alzheimer's Disease [Phase 2]
Phase 2 trial evaluating EVP-0962 for safety, tolerability, and pharmacokinetics, and its effects on cerebrospinal fluid amyloid concentrati…
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CLINICAL_TRIALS trial_result · 2014-01-10Clinical Trial Update: Efficacy of Early Stage Alzheimer's Support Groups [NA]
A completed University of Washington trial evaluated the efficacy of early-stage Alzheimer's support groups.
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Effects of Transcranial Direct Current Stimulation on the Apathy of Alzheimer's Disease [Phase 2]
Phase 2 trial evaluating transcranial direct current stimulation for reducing apathy in Alzheimer's disease; results posted after completion…
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CLINICAL_TRIALS trial_result · 2014-01-01Clinical Trial Update: A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients [Phase 3]
The long-term Phase 3 safety and tolerability study of bapineuzumab in Alzheimer's disease was terminated, with results posted in 2014.
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CLINICAL_TRIALS research · 2013-12-23Clinical Trial Update: Blood-brain Barrier Leakage in Dementia. A Dynamic Contrast-enhanced MRI Study
This clinical trial update describes a study using dynamic contrast-enhanced MRI to investigate blood-brain barrier leakage in dementia. The…
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CLINICAL_TRIALS trial_result · 2013-12-20Clinical Trial Update: A Long-Term Safety and Tolerability Study in Subjects With Mild to Moderate Alzheimer's Disease [Phase 3]
Phase 3 long-term safety and tolerability study in mild to moderate Alzheimer's disease was terminated; sponsor was Janssen Alzheimer's Immu…
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CLINICAL_TRIALS trial_result · 2013-12-19Clinical Trial Update: Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]Flutemetamol Positron Emission Tomography (PET) Images [Phase 3]
Phase 3 trial evaluating an electronic training program for orienting and interpreting [18F]Flutemetamol PET images; results were posted aft…
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CLINICAL_TRIALS trial_result · 2013-12-18Clinical Trial Update: Magnetic Resonance Spectroscopy Study of Memantine in Alzheimer's Disease [Phase 4]
Phase 4 MRI spectroscopy study of memantine in Alzheimer's disease has completed and results were posted in 2013.
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CLINICAL_TRIALS research · 2013-12-17Clinical Trial Update: Cognitive Behavioural Therapy for Persons With MCI or Mild Dementia [NA]
Clinical trial update on Cognitive Behavioral Therapy for people with mild cognitive impairment or mild dementia related to Alzheimer's dise…
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FDA approval · 2013-12-12FDA Approved: AMYVID — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for AMYVID (florbetapir F-18) from Eli Lilly and Company.
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease [Phase 2]
Phase 2 trial update evaluating clinical and immunological activity, safety and tolerability of different doses/formulations of AFFITOPE AD0…
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: VI-1121 for the Treatment Alzheimer's Disease [Phase 2]
A Phase 2 clinical trial of VI-1121 for Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: Safety, Tolerability, and Pharmacokinetics of ABT-354 in Subjects With Mild-to-Moderate Alzheimer's Disease on Stable Doses of Acetylcholinesterase Inhibitors [Phase 1]
Phase 1 study evaluating safety, tolerability, and pharmacokinetics of ABT-354 in subjects with Alzheimer's disease on stable acetylcholines…
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CLINICAL_TRIALS trial_result · 2013-12-11Clinical Trial Update: Observational Follow-up Extension Study of AFF002 and AFF004A in Patients With Alzheimer's Disease
An observational follow-up extension study of AFF002 and AFF004A in Alzheimer's disease has been terminated.