Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-12-10Clinical Trial Update: Blood-brain Barrier Permeability in Alzheimer's Disease
A completed clinical trial conducted at Maastricht University Medical Center investigated blood-brain barrier permeability in individuals wi…
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CLINICAL_TRIALS trial_result · 2013-12-09Clinical Trial Update: Usability Study of Spaced Retrieval Exercise Using Mobile Devices for Alzheimer's Disease Rehabilitation
A completed usability study evaluating spaced retrieval exercises delivered on mobile devices for Alzheimer's disease rehabilitation.
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CLINICAL_TRIALS trial_result · 2013-12-04Clinical Trial Update: Positron Emission Tomography (PET) Imaging of Brain Amyloid Compared to Post-Mortem Levels [Phase 3]
GE Healthcare's Phase 3 trial evaluated PET imaging of brain amyloid and compared imaging results to post-mortem levels; the study has compl…
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CLINICAL_TRIALS trial_result · 2013-12-02Clinical Trial Update: Impact of a Memory Group for Older Adults Reporting Memory Difficulties [NA]
A completed clinical trial update evaluating the impact of a memory-group intervention for older adults reporting memory difficulties. The s…
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CLINICAL_TRIALS research · 2013-11-27Clinical Trial Update: Multiple Nutritional Deficiencies Causing Dementia of the Alzheimer Type
This clinical trial update describes research investigating whether multiple nutritional deficiencies can contribute to dementia of the Alzh…
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CLINICAL_TRIALS trial_result · 2013-11-26Clinical Trial Update: A Confirmatory Trial of SK-PC-B70M in Mild to Moderate Alzheimer's Disease [Phase 3]
A Phase 3 confirmatory trial of SK-PC-B70M in mild to moderate Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: AAB-001 (Bapineuzumab) Open-Label, Long-Term Extension Study in Patients With Mild to Moderate Alzheimer's Disease [Phase 2]
This clinical trial update reports the termination of a Phase 2 open-label long-term extension study of bapineuzumab in patients with mild t…
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Non-Carrier) [Phase 3]
Phase 3 trial update for bapineuzumab in mild-to-moderate Alzheimer's disease, focusing on ApoE4 non-carriers. The study has completed.
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Bapineuzumab in Patients With Mild to Moderate Alzheimer's Disease (ApoE4 Carrier) [Phase 3]
This entry reports the completion of a Phase 3 trial of bapineuzumab in mild-to-moderate Alzheimer's disease (ApoE4 carriers).
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CLINICAL_TRIALS trial_result · 2013-11-25Clinical Trial Update: Construction-LBD (Constructional Apraxia in Alzheimer's Disease (AD) and Lewy Body's Dementia (LBD)) [NA]
An update on the Construction-LBD clinical trial for constructional apraxia in Alzheimer's disease and dementia with Lewy bodies, sponsored …
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CLINICAL_TRIALS trial_result · 2013-11-20Clinical Trial Update: Correlation Between Regional Brain Volume and Response to Donepezil Treatment in AD Patients [Phase 4]
This Phase 4 trial update reports termination of a study examining whether regional brain volume predicts response to donepezil in Alzheimer…
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CLINICAL_TRIALS trial_result · 2013-11-15Clinical Trial Update: Study Evaluating Bapineuzumab In Alzheimer Disease Subjects [Phase 2]
Pfizer completed a Phase 2 study evaluating bapineuzumab in Alzheimer's disease. Results were posted in 2013.
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FDA approval · 2013-11-14FDA Approved: MEMANTINE HYDROCHLORIDE — Supplemental Application (Actavis Pharma, Inc.)
The FDA approved a supplemental application for memantine hydrochloride submitted by Actavis Pharma, resulting in an approved modification t…
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CLINICAL_TRIALS trial_result · 2013-11-13Clinical Trial Update: A Comparison of Two Standard Therapies in the Management of Dementia With Agitation [Phase 4]
Phase 4 clinical trial comparing two standard therapies for agitation in dementia has completed; the provided document does not include tria…
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Intramuscular Aripiprazole in Acutely Agitated Patients Diagnosed With Dementia [Phase 3]
Phase 3 trial of intramuscular aripiprazole for acute agitation in dementia patients (including Alzheimer's disease) has completed.
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Evaluation of [18F] PBR111 and PET as a Marker of Inflammation in Subjects With Neurological Conditions [Phase 1]
Phase 1 trial evaluating the PET tracer [18F] PBR111 as a marker of brain inflammation in Alzheimer's disease; the study has completed.
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type [Phase 3]
Phase 3 trial of aripiprazole for psychosis in Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type [Phase 3]
A Phase 3 study evaluating aripiprazole for psychosis in patients with Alzheimer's-type dementia has completed.
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CLINICAL_TRIALS trial_result · 2013-11-11Clinical Trial Update: Evaluation of [18F] FMH3 and PET as a Marker of Histamine-3 Receptor Activity in Subjects With AD Compared w/ HC [EARLY_Phase 1]
This clinical trial update reports the completion of a Phase 1 study evaluating the PET radiotracer [18F] FMH3 to assess histamine-3 recepto…
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FDA approval · 2013-11-08FDA Approved: AMYVID — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for AMYVID (florbetapir F-18) by Eli Lilly, updating its use as an imaging agent to estimate beta-am…
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FDA approval · 2013-11-07FDA Approved: DONEPEZIL HYDROCHLORIDE — Supplemental Application (Macleods Pharmaceuticals Limited)
The FDA approved a supplemental application for Donepezil Hydrochloride from Macleods Pharmaceuticals Limited, enabling the marketing of the…
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: Follow-up Study to Evaluate Long-term Safety and Tolerability of Immunization With AD03 Applied During AFF005A
A follow-up study evaluating the long-term safety and tolerability of the AD03 immunization used during AFF005A for Alzheimer's disease has …
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CLINICAL_TRIALS trial_result · 2013-11-05Clinical Trial Update: Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease [Phase 2]
Phase 2 trial evaluating T-817MA for mild to moderate Alzheimer's disease has completed, reporting efficacy and safety findings.
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EMA guidance · 2013-10-31Comments invited on concept paper on the need to revise the guideline on medicines to treat Alzheimer's disease
EMA invites comments on a concept paper proposing revisions to the guideline for medicines that treat Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2013-10-29Clinical Trial Update: An Evaluation of Three Doses of NS 2330 in Patients With Mild to Moderate Dementia of the Alzheimer's Type [Phase 2]
This update reports results from a Phase 2 trial evaluating three doses of NS 2330 in patients with mild to moderate Alzheimer's disease.