Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-04-23Clinical Trial Update: Safety and Tolerability of Etanercept in Alzheimer's Disease [Phase 2]
Phase 2 clinical trial update evaluating the safety and tolerability of etanercept in Alzheimer's disease has been reported. The update summ…
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CLINICAL_TRIALS trial_result · 2014-04-22Clinical Trial Update: Effects of Exercise Training in Patients With Mild Cognitive Impairment
A completed clinical trial investigating the effects of exercise training in patients with mild cognitive impairment, with Alzheimer's disea…
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CLINICAL_TRIALS trial_result · 2014-04-22Clinical Trial Update: Cerebrospinal Fluid (CSF) Biomarkers Alzheimer's Disease (AD) and Non-AD Dementias
Clinical trial update reporting on a completed study evaluating cerebrospinal fluid biomarkers in Alzheimer's disease and non-Alzheimer's de…
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Effects of Exercise Training in Patients With Mild Cognitive Impairment and Early Alzheimer's Disease [NA]
Clinical trial update on the effects of exercise training in patients with Mild Cognitive Impairment and early Alzheimer's disease; the stud…
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Effect of NeuroAD on Alzheimer Patients [NA]
Clinical trial update showing completion of a study evaluating NeuroAD in Alzheimer's disease; no results are provided in the snippet.
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CLINICAL_TRIALS research · 2014-04-16Clinical Trial Update: PRISM Registry: Pseudobulbar Affect Registry Series
The PRISM Registry update for pseudobulbar affect has completed. Avanir Pharmaceuticals sponsored the registry, which collected PBA data acr…
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EMA guidance · 2014-04-11Registration opens for EMA workshop on the clinical investigation of medicines for the treatment of Alzheimer's disease
EMA announces a workshop registration about the clinical investigation of medicines for Alzheimer's disease, providing information and parti…
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CLINICAL_TRIALS research · 2014-04-09Clinical Trial Update: Imaging of New Learning in Severe Alzheimer's Disease Patients [NA]
This entry provides an update on a clinical trial investigating imaging of new learning in patients with severe Alzheimer's disease; the cur…
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CLINICAL_TRIALS trial_result · 2014-04-09Clinical Trial Update: Yogic Breathing Changes Salivary Components [NA]
This completed clinical trial examined whether yogic breathing changes salivary components.
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CLINICAL_TRIALS research · 2014-04-09Clinical Trial Update: Prospective Memory Imaging [NA]
This document reports a clinical trial update for prospective memory imaging in Alzheimer's disease. The trial phase and current status are …
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CLINICAL_TRIALS trial_result · 2014-04-03Clinical Trial Update: A Two-part Multiple Dose Study to Assess the Safety and Effects of AZD3293 in Healthy Elderly and Alzheimer's Patients [Phase 1]
This document reports the completion of a Phase 1 two-part multiple-dose study evaluating the safety and effects of AZD3293 (lanabecestat) i…
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Evaluation of Efficacy and Safety of Galantamine in Patients With Dementia of Alzheimer's Type Who Failed to Benefit From Donepezil [Phase 4]
Phase 4 trial assessing the efficacy and safety of galantamine in Alzheimer's disease patients who did not benefit from donepezil.
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CLINICAL_TRIALS safety_alert · 2014-03-20Clinical Trial Update: Inappropriate Medications Associated With Anticholinesterase and/or Memantine Treatment in the Elderly
A clinical trial update highlighting inappropriate prescribing among elderly patients treated with acetylcholinesterase inhibitors and/or me…
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FDA approval · 2014-03-19FDA Approved: NEURACEQ — Original Application (Lantheus Biosciences Ltd.)
FDA approved NEURACEQ (florbetaben F-18) for PET imaging to estimate beta-amyloid neuritic plaque density in adults with cognitive impairmen…
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CLINICAL_TRIALS trial_result · 2014-03-18Clinical Trial Update: A Study to Measure CSF Proteins in Elderly Healthy Volunteers and Volunteers With Mild Cognitive Impairment or Alzheimer's Disease [EARLY_Phase 1]
This completed early-phase trial measured cerebrospinal fluid proteins in elderly healthy volunteers and participants with mild cognitive im…
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FDA label_change · 2014-03-14FDA Approved: AMYVID — Supplemental Application (Eli Lilly and Company)
FDA approved a supplemental application for AMYVID (Florbetapir F-18) by Eli Lilly, updating the labeling for its use as an amyloid imaging …
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CLINICAL_TRIALS withdrawal · 2014-03-13Clinical Trial Update: Efficacy of Pulsatile IV Insulin on Cognition and Amyloid Burden in Patients With Alzheimer's Disease [NA]
The trial investigating pulsatile intravenous insulin for Alzheimer's disease and mild cognitive impairment has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-03-10Clinical Trial Update: Evaluation of a Handheld Event Related Potential (ERP)/Quantitative Electroencephalography (qEEG) System (COGNISION™) as a Useful Cognitive Biomarker for Alzheimer's Disease.
The study evaluates the COGNISION handheld ERP/qEEG system as a potential cognitive biomarker for Alzheimer's disease. The trial by Neuronet…
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CLINICAL_TRIALS trial_result · 2014-03-07Clinical Trial Update: Assess 123-I IMPY and SPECT Imaging as a Tool to Detect β-Amyloid in the Brain [Phase 1]
Phase 1 clinical trial evaluating 123I IMPY with SPECT imaging to detect beta-amyloid in the brain for Alzheimer's disease has been complete…
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CLINICAL_TRIALS trial_result · 2014-03-03Clinical Trial Update: Treatment for Early Memory Loss [Phase 4]
A Phase 4 clinical trial addressing early memory loss has completed. The update does not provide the trial's results.
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CLINICAL_TRIALS trial_result · 2014-02-28Clinical Trial Update: Effect of Exercises Training in Patients With Mild Cognitive Impairment and Early Alzheimer's Disease [NA]
This update summarizes a completed clinical trial evaluating the effects of exercise training in people with mild cognitive impairment and e…
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CLINICAL_TRIALS trial_result · 2014-02-20Clinical Trial Update: [18F]MK-3328 as a Possible Novel Positron Emission Tomography (PET) Tracer for the Detection of Brain Amyloid Plaques (MK-3328-002) [Phase 1]
Phase 1 clinical trial evaluating [18F]MK-3328 as a potential PET tracer for detecting brain amyloid plaques in Alzheimer's disease; trial t…
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CLINICAL_TRIALS research · 2014-02-19Clinical Trial Update: The Study of microRNA 107 (miRNA 107) and Beta-amyloid Precursor Protein-cleaving Enzyme 1 (BACE1) Messenger Ribonucleic Acid (mRNA) Gene Expression in Cerebrospinal Fluid and Peripheral Blood of Alzheimer's Disease
This study examines miRNA-107 and BACE1 mRNA expression in cerebrospinal fluid and peripheral blood of individuals with Alzheimer’s disease …
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CLINICAL_TRIALS trial_result · 2014-02-14Clinical Trial Update: Genes, Exercise, Memory and Neurodegeneration [NA]
A completed study sponsored by Howard University explored the roles of genes, exercise, and memory in Alzheimer's disease neurodegeneration.
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CLINICAL_TRIALS trial_result · 2014-02-06Clinical Trial Update: Evaluation of Safety & Tolerability of Multiple Dose Regimens of CHF 5074 and Exploration of Effects on Potential Markers of Clinical Efficacy in Patients With Mild Cognitive Impairment - Prolonged Open Label Extension Phase [Phase 2]
Phase 2 study evaluating safety, tolerability, and potential efficacy markers for CHF 5074 in mild cognitive impairment and Alzheimer's dise…