Alveolar Soft Part Sarcoma

• CLINICAL_TRIALS trial_result · 2026-03-23
  Clinical Trial Update: GPNMB-targeting Chimeric Antigen Receptor T-Cell Therapy (GCAR1) for a Patient With Alveolar Soft Part Sarcoma (CLIC-YYC-GPNMB-02) [EARLY_Phase 1]

  An early-phase 1 trial of GCAR1, a GPNMB-targeting CAR T-cell therapy, for alveolar soft part sarcoma; the study is currently active but not…

• CLINICAL_TRIALS trial_result · 2025-11-14
  Clinical Trial Update: A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies. [Phase 1]

  This Phase 1 trial of FAZ053 as a single agent and in combination with PDR001 in patients with advanced malignancies has been terminated.

• CLINICAL_TRIALS trial_result · 2025-08-05
  Clinical Trial Update: A Study to Determine the Safety and Effectiveness of the Investigational Cellular Therapy GCAR1 in a Patient With Alveolar Soft Part Sarcoma [EARLY_Phase 1]

  An early-phase clinical trial is evaluating the investigational cellular therapy GCAR1 for alveolar soft part sarcoma, but the study is not …

• CLINICAL_TRIALS trial_result · 2025-07-23
  Clinical Trial Update: GPNMB-targeting Chimeric Antigen Receptor T-Cell Therapy (GCAR1) for a Patient With Alveolar Soft Part Sarcoma [EARLY_Phase 1]

  An early-phase trial update reports results of GCAR1, a GPNMB-targeting CAR-T cell therapy, in a patient with alveolar soft part sarcoma.

• CLINICAL_TRIALS trial_result · 2025-04-10
  Clinical Trial Update: CAR T Therapy With GCAR1 for Relapsed Alveolar Soft Part Sarcoma [EARLY_Phase 1]

  An early-phase 1 trial of GCAR1 CAR T therapy for relapsed alveolar soft part sarcoma is ongoing, sponsored by the University of Calgary, wi…

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• CLINICAL_TRIALS trial_result · 2024-09-19
  Clinical Trial Update: Sunitinib or Cediranib for Alveolar Soft Part Sarcoma [Phase 2]

  A Phase 2 trial evaluating sunitinib and cediranib for alveolar soft part sarcoma has completed and results are posted.

• CLINICAL_TRIALS trial_result · 2023-12-11
  Clinical Trial Update: CREATE: Cross-tumoral Phase 2 With Crizotinib [Phase 2]

  Phase 2 cross-tumor trial evaluating crizotinib in multiple locally advanced or metastatic cancers; study completed.

• CLINICAL_TRIALS trial_result · 2022-11-28
  Clinical Trial Update: Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors [Phase 2]

  A Phase 2 clinical trial evaluating cabozantinib-s-maleate in pediatric patients with recurrent, refractory, or newly diagnosed sarcomas, Wi…

• CLINICAL_TRIALS trial_result · 2021-11-26
  Clinical Trial Update: Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas [Phase 2]

  Phase 2 trial evaluating axitinib in combination with pembrolizumab in advanced alveolar soft part sarcoma and other soft tissue sarcomas ha…

• CLINICAL_TRIALS trial_result · 2021-04-27
  Clinical Trial Update: Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma [Phase 2]

  Phase II trial update reporting results for Cediranib (AZD2171) in alveolar soft part sarcoma; study completed and results posted.

• CLINICAL_TRIALS trial_result · 2021-03-03
  Clinical Trial Update: Clinical Trial in Chinese Patients of Elapsed/Metastatic/Unresectable Alveolar Soft Part Sarcoma(GB226) [Phase 2]

  Phase 2 clinical trial update in Chinese patients with alveolar soft part sarcoma (GB226).

• CLINICAL_TRIALS trial_result · 2020-06-25
  Clinical Trial Update: A Study of Carilizumab in Combination With Apatinib in Subjects With Unresectable UPS and ASPS [Phase 2]

  Phase 2 trial update investigating carilizumab in combination with apatinib for unresectable undifferentiated pleomorphic sarcoma and alveol…

• CLINICAL_TRIALS trial_result · 2018-03-07
  Clinical Trial Update: A Trial of Perifosine in Patients With Chemo-Insensitive Sarcomas [Phase 2]

  Phase 2 trial evaluating perifosine in chemo-insensitive sarcomas, including chondrosarcoma, alveolar soft-part sarcoma, and extraskeletal m…

• CLINICAL_TRIALS trial_result · 2017-11-06
  Clinical Trial Update: Pazopanib for Metastatic Alveolar Soft Part Sarcoma [Phase 2]

  Phase 2 trial of Pazopanib for metastatic alveolar soft-part sarcoma has been terminated.

• CLINICAL_TRIALS trial_result · 2017-05-12
  Clinical Trial Update: Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma [Phase 2]

  Phase 2 clinical trial update for romidepsin (depsipeptide) in patients with metastatic or unresectable soft tissue sarcoma, with results po…

• CLINICAL_TRIALS trial_result · 2016-07-22
  Clinical Trial Update: Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma [Phase 1, Phase 2]

  Phase 1/Phase 2 trial evaluating vismodegib with RO4929097 targeting Hedgehog and Notch pathways in various advanced/metastatic soft tissue …

• CLINICAL_TRIALS trial_result · 2013-02-08
  Clinical Trial Update: Phase 2 Study in Patients With MiT Tumors [Phase 2]

  Phase 2 study of tivantinib in MiT family tumors including renal cell carcinoma, alveolar soft part sarcoma, and clear cell sarcoma has been…