Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-05-28Clinical Trial Update: French Evaluation Group Avastin Versus Lucentis [Phase 3]
Phase 3 trial comparing Avastin to Lucentis for age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: A Study Investigating the Efficacy and Safety of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration [Phase 3]
Phase 3 trial of lampalizumab for geographic atrophy due to age-related macular degeneration was terminated with posted results in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: A Safety and Efficacy Study of Brimonidine Intravitreal Implant in Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 2]
Phase 2 safety and efficacy trial of brimonidine intravitreal implant for geographic atrophy due to age-related macular degeneration was ter…
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CLINICAL_TRIALS trial_result · 2019-03-21Clinical Trial Update: Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection [NA]
A completed pilot randomized trial evaluating anesthetic agents for intravitreal injections in macular degeneration; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-03-14Clinical Trial Update: A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration [Phase 3]
Phase 3 trial investigating lampalizumab for geographic atrophy due to age-related macular degeneration was terminated; results posted in 20…
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: A 24 Month Phase 2a Open Label, Randomized Study of Avastin®, Lucentis®, or Eylea® (Anti-VEGF Therapy) Administered in Combination With Fovista® (Anti-PDGF BB Pegylated Aptamer) [Phase 2]
A 24-month Phase 2a open-label randomized study evaluated Avastin, Lucentis, or Eylea in combination with Fovista for age-related macular de…
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CLINICAL_TRIALS trial_result · 2019-02-21Clinical Trial Update: Intravitreal Aflibercept for Submacular Hemorrhage [Phase 4]
The document reports the completion of a Phase 4 clinical trial evaluating intravitreal aflibercept for submacular hemorrhage in exudative a…
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CLINICAL_TRIALS trial_result · 2019-02-20Clinical Trial Update: Efficacy and Safety of Lucentis® (Ranibizumab Intravitreal Injections) in Chilean Patients With Diabetic Macular Edema. [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of Lucentis (ranibizumab) in Chilean patients with diabetic macular edema has comp…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT) [Phase 3]
Phase 3 trial update on long-term safety of lampalizumab intravitreal injections in geographic atrophy due to age-related macular degenerati…
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: Measuring Geographic Atrophy in AMD Patients Using the Nidek MP-3 Microperimetry Device
A completed clinical trial evaluating geographic atrophy measurements in age-related macular degeneration using the Nidek MP-3 microperimetr…
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CLINICAL_TRIALS trial_result · 2019-02-07Clinical Trial Update: Brain Connectivity in Age-Related Macular Degeneration
A Duke University–sponsored clinical trial investigating brain connectivity in age-related macular degeneration has completed.
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: Enhancing the Lucentis (Ranibizumab) Management of Choroidal Neovascular Membranes With Hyperspectral Imaging
A clinical trial evaluating hyperspectral imaging to enhance management of choroidal neovascular membranes in age-related macular degenerati…
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CLINICAL_TRIALS trial_result · 2019-02-01Clinical Trial Update: Prevalence of Age Related Macular Degeneration (ARMD) in Parkinson's Patients and Assesment of the Role of L-DOPA
This clinical trial update summarizes a completed study evaluating the prevalence of age-related macular degeneration in Parkinson disease p…
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CLINICAL_TRIALS research · 2019-01-30Clinical Trial Update: Polarization Perception in Health and Disease. Testing a New Sight Test
An update on a clinical trial investigating a new sight test to measure polarization perception in eye diseases such as cataract and age-rel…
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CLINICAL_TRIALS trial_result · 2019-01-23Clinical Trial Update: OCT and Microperimetry in Patients With Active Neovascular ARMD (CORFI)
This clinical trial update describes a study evaluating OCT and microperimetry in patients with active neovascular age-related macular degen…
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Effect Aflibercept on Ocular Perfusion [Phase 4]
Phase 4 trial update investigating the effect of aflibercept on ocular perfusion in macular degeneration.
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CLINICAL_TRIALS trial_result · 2019-01-10Clinical Trial Update: Intense Treatment Regimen With Intravitreal Aflibercept Injection [Phase 1, Phase 2]
Phase 1/2 trial evaluating an intense intravitreal aflibercept treatment regimen for neovascular age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2018-09-17Clinical Trial Update: Safety and Preliminary Efficacy Study of WST11 (Stakel®)-Mediated VTP Therapy in Subjects With CNV Associated With AMD [Phase 2]
Phase 2 safety and preliminary efficacy study of WST11-mediated VTP therapy in CNV associated with AMD was terminated; results posted in 201…
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CLINICAL_TRIALS trial_result · 2018-09-07Clinical Trial Update: To Evaluate The Role of Intravitreal Aflibercept Injection (2.0 mg) in the Management of Previously Treated Patients With Exudative AMD [Phase 4]
Phase 4 trial evaluating intravitreal aflibercept (2.0 mg) for previously treated exudative AMD with persistent or recurrent fluid.
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CLINICAL_TRIALS trial_result · 2018-08-29Clinical Trial Update: Ziv-aflibercept in Ocular Disease Requiring Anti-VEGF Injection [Phase 2]
Phase 2 trial update for Ziv-aflibercept in ocular diseases requiring anti-VEGF injections.
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CLINICAL_TRIALS trial_result · 2018-08-28Clinical Trial Update: Prophylactic Ranibizumab for Exudative Age-Related Macular Degeneration [Phase 1, Phase 2]
Phase 1/2 trial evaluating prophylactic ranibizumab for exudative age-related macular degeneration has completed.
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FDA approval · 2018-08-16FDA Approved: EYLEA — Supplemental Application (Regeneron Pharmaceuticals, Inc.)
FDA has approved a supplemental application for EYLEA (aflibercept) from Regeneron Pharmaceuticals, Inc. The approval indicates the suppleme…
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CLINICAL_TRIALS trial_result · 2018-08-15Clinical Trial Update: A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy [Phase 3]
A Phase 3 study evaluating Fovista (E10030) plus Lucentis versus Lucentis alone in age-related macular degeneration was terminated, with res…
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CLINICAL_TRIALS trial_result · 2018-08-10Clinical Trial Update: A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy [Phase 3]
A Phase 3 study evaluating the safety and efficacy of Fovista (E10030) in combination with Lucentis versus Lucentis alone for age-related ma…
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial [Phase 2, Phase 3]
A phase 2/3 trial is investigating whether combining propranolol with bevacizumab for intravitreal injection improves treatment response in …