Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-08-03Clinical Trial Results: A Clinical Effectiveness Study Examining the Efficacy and Safety of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 clinical trial results evaluating the efficacy and safety of ONS-5010 in subjects with neovascular age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2026-07-29Clinical Trial Results: Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration [NA]
Clinical trial results for retinal fundus flavoprotein fluorescence in geographic atrophy and age-related macular degeneration have been com…
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CLINICAL_TRIALS trial_result · 2026-07-17Clinical Trial Results: A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders [Phase 3]
Phase 3 trial assessing the safety of ONS-5010 in subjects with visual impairment due to retinal disorders completed with results posted.
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CLINICAL_TRIALS trial_result · 2026-06-30Clinical Trial Results: A 3-month Study to Assess the Safety and Effectiveness of ONS-5010 in Subjects With Neovascular Age-related Macular Degeneration (AMD) [Phase 3]
Phase 3 trial results for ONS-5010 in neovascular age-related macular degeneration completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-04-28Clinical Trial Update: Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD [Phase 2, Phase 3]
Pivotal Phase 2/3 study of ABBV-RGX-314 (RGX-314) gene therapy for neovascular age-related macular degeneration evaluates subretinal deliver…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Age-Related Eye Disease Study (AREDS) Follow-Up
The AREDS follow-up trial is currently active but not recruiting participants.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Cell Collection to Study Eye Diseases
An NEI-sponsored clinical trial update describes cell collection to study eye diseases, including age-related macular degeneration, retinal …
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Serum Cholinesterases, Paraoxonase, and Cardiovascular Risk After Intravitreal Bevacizumab
Clinical trial investigating the effects of intravitreal bevacizumab on serum cholinesterases, paraoxonase, and cardiovascular risk in patie…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Study to Evaluate the Usability of the SB11 PFS in Trial Participants With Wet AMD, Macular Oedema Secondary to RVO, or mCNV [Phase 2]
Phase 2 study evaluating the usability of the SB11 prefilled syringe (ranibizumab biosimilar) in participants with wet age-related macular d…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Dark Adaptation in Participants With Age-Related Macular Degeneration
NEI-sponsored clinical trial assessing dark adaptation in participants with age-related macular degeneration is currently active but not rec…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) [Phase 2, Phase 3]
EyeBiotech's MK-8748 (EYE201) is in a Phase 2/3 trial for macular degeneration, including age-related macular degeneration, with recruitment…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders [Phase 3]
A Phase 3 trial comparing the safety of ONS-5010 when administered from vials versus pre-filled syringes in adults with retinal disorders ca…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) [Phase 2, Phase 3]
Phase 2/3 trial MK-8748 (EYE201) for age-related macular degeneration is described in this update. The study status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Visual Remapping to Aid Reading With Field Loss [NA]
A University of Minnesota-led clinical trial is evaluating Visual Remapping to Aid Reading With Field Loss for Age-related Macular Degenerat…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Safety and Clinical Applicability of Transcorneal Electrical Stimulation (TES) in Geographic Atrophy [NA]
Clinical trial update on safety and clinical applicability of transcorneal electrical stimulation for Geographic Atrophy due to age-related …
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Phase 2 Study of ADX-038 in Participants With Geographic Atrophy [Phase 2]
Phase 2 trial of ADX-038 for geographic atrophy secondary to age-related macular degeneration is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Optimize Subretinal Surgical Delivery and to Evaluate Safety and Activity of Opregen in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GAlette); Adaptive Optics (AO) Retinal Imaging Substudy in Association With Study GR44251 [Phase 2]
Phase 2 study update evaluating Opregen for Geographic Atrophy due to Age-related Macular Degeneration, including optimization of subretinal…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
A ClinicalTrials.gov study is recruiting to observe how Avacincaptad Pegol (Izervay) is used in clinical practice for geographic atrophy and…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration [Phase 1, Phase 2]
A one-time intravitreal injection of SAR446597 for Geographic Atrophy due to Age-related Macular Degeneration is in a combined Phase 1/2 tri…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD [Phase 3]
Phase 3 pivotal study update on RGX-314 gene therapy for neovascular age-related macular degeneration (nAMD), with recruitment ongoing under…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Ocular Imaging Study Using Advanced OCT
This document provides an update on a UCLA-sponsored clinical trial evaluating advanced Optical Coherence Tomography imaging for retinal dis…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy [Phase 1, Phase 2]
A safety surveillance study of human embryonic stem cell–derived retinal pigment epithelium cell therapy for age-related macular degeneratio…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Avacincaptad Pegol Open-Label Extension for Patients With Geographic Atrophy [Phase 3]
An open-label extension of avacincaptad pegol in geographic atrophy has completed Phase 3, with results posted on April 14, 2026. The study …
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration [NA]
Clinical trial update indicating that Microcurrent Stimulation Therapy is recruiting for intermediate to advanced nonexudative age-related m…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) [Phase 2]
A long-term extension Phase 2 trial update for Janssen's gene therapy JNJ-81201887 (AAVCAGsCD59) in geographic atrophy due to age-related ma…