Age-related Macular Degeneration
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-07-28Clinical Trial Update: A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration [Phase 3]
Phase 3 trial investigating safety and efficacy of Abicipar Pegol in neovascular age-related macular degeneration has completed with results…
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CLINICAL_TRIALS research · 2020-07-22Clinical Trial Update: Stem Cell Therapy for Outer Retinal Degenerations [Phase 1, Phase 2]
A completed early-stage trial investigating stem cell therapy for age-related macular degeneration and Stargardt's disease.
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CLINICAL_TRIALS trial_result · 2020-06-23Clinical Trial Update: A Study to Evaluate the Safety and Clinical Response of Subretinal Administration of CNTO 2476 in Participants With Geographic Atrophy [Phase 2]
Phase 2 trial update on subretinal administration of CNTO 2476 in geographic atrophy, reporting safety and clinical response outcomes with r…
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CLINICAL_TRIALS trial_result · 2020-05-27Clinical Trial Update: Cooling Anesthesia for Intravitreal Injection [Phase 1, Phase 2]
Clinical trial update on cooling anesthesia for intravitreal injection showing completed Phase 1 and Phase 2 studies.
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CLINICAL_TRIALS trial_result · 2020-05-21Clinical Trial Update: Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye [Phase 4]
Phase 4 clinical trial evaluating 2 mg intravitreal aflibercept with different dosing schedules for wet age-related macular degeneration ove…
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CLINICAL_TRIALS trial_result · 2020-05-19Clinical Trial Update: Efficacy and Safety of "Treat-and-Extend" Regimen Versus "Pro Re Nata" of Conbercept in Age-related Macular Degeneration [Phase 4]
Phase 4 trial comparing Treat-and-Extend versus Pro Re Nata regimens of conbercept for age-related macular degeneration; efficacy and safety…
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CLINICAL_TRIALS trial_result · 2020-04-01Clinical Trial Update: Efficacy of Acupuncture in Macular Diseases [NA]
A completed clinical trial evaluating acupuncture for macular diseases (age-related macular degeneration and Stargardt disease) with results…
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study) [Phase 4]
Phase 4 trial comparing povidone iodine disinfection to AVEnova in pre-injection procedures for retinal diseases; completed.
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CLINICAL_TRIALS trial_result · 2020-02-17Clinical Trial Update: Subthreshold Laser Treatment for Reticular Pseudodrusen and Geographic Atrophy Secondary to AMD [NA]
Completed results for a trial of subthreshold laser treatment for reticular pseudodrusen and geographic atrophy due to age-related macular d…
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration [Phase 1, Phase 2]
Phase I/II study assessing safety, tolerability, immunogenicity, and bioactivity of DE-122 injectable solution for refractory exudative age-…
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CLINICAL_TRIALS trial_result · 2020-01-13Clinical Trial Update: Safety and Tolerability of Oral CM082 in Patients With wAMD [Phase 2]
Phase 2 study evaluating safety and tolerability of oral CM082 in patients with age-related macular degeneration.
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CLINICAL_TRIALS trial_result · 2019-12-04Clinical Trial Update: Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)
Clinical trial completed investigating rod sensitivity in age-related macular degeneration and retinitis pigmentosa; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-12-03Clinical Trial Update: Dorzolamide-timolol Drops With Injections to Treat AMD, RVO or DME. [Phase 2]
Phase 2 trial evaluating dorzolamide-timolol drops administered with injections for wet AMD, age-related macular degeneration, diabetic macu…
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FDA approval · 2019-10-07FDA Approved: BEOVU — Original Application (Novartis Pharmaceuticals Corporation)
The FDA approved BEOVU (brolucizumab) under an original application from Novartis Pharmaceuticals Corporation for the treatment of neovascul…
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CLINICAL_TRIALS research · 2019-09-30Clinical Trial Update: Complement Factor H Haplotypes and Smoking in Age-related Macular Degeneration
A completed clinical trial investigating the relationship between Complement Factor H haplotypes, smoking, and age-related macular degenerat…
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: Clinical Assessment Of Age-related Macular Degeneration Patients After Early Diagnosis and Treatment With Ranibizumab [Phase 2, Phase 3]
A Phase 2/3 clinical trial evaluating ranibizumab for age-related macular degeneration was terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-15Clinical Trial Update: Ranibizumab In Pigment Epithelium Tears Secondary To Age-Related Macular Degeneration Study [Phase 2]
Phase 2 trial update of ranibizumab for pigment epithelium tears associated with age-related macular degeneration; study completed with resu…
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CLINICAL_TRIALS trial_result · 2019-08-14Clinical Trial Update: Study EvAluating Genotypes While Using Lucentis 2 [Phase 4]
Phase 4 trial update evaluating genotypes while using Lucentis for age-related macular degeneration; study completed with results posted in …
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: S0000B: Vitamin E and/or Selenium in Preventing Cataract and Age-Related Macular Degeneration in Men on SELECT SWOG-S0000 [Phase 3]
Phase 3 trial evaluating vitamin E and/or selenium for preventing cataract and age-related macular degeneration in men; study completed with…
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CLINICAL_TRIALS trial_result · 2019-07-22Clinical Trial Update: Macular EpiRetinal Brachytherapy Versus Lucentis® Only Treatment (MERLOT) [Phase 4]
Phase 4 trial update comparing Macular Epiretinal Brachytherapy to Lucentis-only treatment for macular degeneration; results have been poste…
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: HOme Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device [NA]
Clinical trial update on home vision monitoring (ForeseeHome) for progression to neovascular age-related macular degeneration in AREDS2 part…
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CLINICAL_TRIALS trial_result · 2019-07-10Clinical Trial Update: Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMD [Phase 2]
Phase 2A open-label safety study of Fovista in combination with anti-VEGF therapy for sub-retinal fibrosis in neovascular age-related macula…
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CLINICAL_TRIALS trial_result · 2019-06-25Clinical Trial Update: Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections [NA]
A completed clinical trial evaluating topical proparacaine eye drops to improve patient experience during intravitreal injections for age-re…
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CLINICAL_TRIALS trial_result · 2019-06-07Clinical Trial Update: Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT) [Phase 4]
Phase 4 trial comparing ranibizumab monotherapy versus ranibizumab combined with verteporfin photodynamic therapy for symptomatic macular po…
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patients [Phase 4]
Phase 4 clinical trial comparing ranibizumab and aflibercept for development of geographic atrophy in wet age-related macular degeneration; …