Adrenocortical Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-05-17Clinical Trial Update: Phase II Trial of ZD1839 (Iressa) in Patients With Nonresectable Adrenocortical Carcinoma (ACC) [Phase 2]
A Phase II study evaluating ZD1839 (Iressa) in patients with nonresectable adrenocortical carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: Antineoplaston Therapy in Treating Patients With Stage IV Adrenal Gland Cancer [Phase 2]
Phase 2 trial of antineoplaston therapy for Stage IV adrenocortical carcinoma was terminated; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: Cabazitaxel Activity in Patients With Advanced AdrenoCortical-Carcinoma Progressing After Previous Chemotherapy Lines [Phase 2]
Phase 2 trial evaluating cabazitaxel in patients with advanced adrenocortical carcinoma progressing after prior chemotherapy shows activity.…
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CLINICAL_TRIALS trial_result · 2017-11-06Clinical Trial Update: Phase 1 Study of ATR-101 in Subjects With Advanced Adrenocortical Carcinoma [Phase 1]
This update reports the completion of a Phase 1 study of ATR-101 in adults with advanced Adrenocortical Carcinoma.
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CLINICAL_TRIALS research · 2017-05-10Clinical Trial Update: Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma [Phase 2]
Phase 2 clinical trial update evaluating abiraterone acetate for managing Cushing's syndrome in patients with adrenocortical carcinoma; curr…
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FDA approval · 2017-05-09FDA Approved: LYSODREN — Supplemental Application (ESTEVE PHARMACEUTICALS, S.A.)
The FDA approved a supplemental application for LYSODREN (mitotane) filed by ESTEVE Pharmaceuticals, S.A.
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: Efficacy of Adjuvant Mitotane Treatment (ADIUVO) [Phase 3]
Phase 3 trial ADIUVO evaluating adjuvant mitotane for adrenocortical carcinoma; the update notes the trial status as UNKNOWN.
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Clinical Trial of Dovitinib in First-line Metastatic or Locally Advanced Non-resectable Adrenocortical Carcinoma [Phase 2]
A Phase 2 trial of dovitinib as first-line treatment for metastatic or locally advanced non-resectable adrenocortical carcinoma has complete…
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CLINICAL_TRIALS trial_result · 2017-02-09Clinical Trial Update: Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
A completed natural history study followed infants with adrenal masses detected prenatally or neonatally to document disease course for adre…
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CLINICAL_TRIALS trial_result · 2016-09-21Clinical Trial Update: Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT) [Phase 3]
Phase 3 trial in locally advanced or metastatic adrenocortical carcinoma completed; results were posted in 2016 as part of the FIRM-ACT stud…
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CLINICAL_TRIALS research · 2016-05-18Clinical Trial Update: Studying Genes in Samples From Younger Patients With Adrenocortical Tumor
The Children's Oncology Group completed a clinical trial studying gene expression in samples from younger patients with adrenocortical tumor…
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FDA label_change · 2016-03-11FDA Approved: LYSODREN — Supplemental Application (ESTEVE PHARMACEUTICALS, S.A.)
FDA approved a supplemental application for LYSODREN (mitotane) submitted by ESTEVE Pharmaceuticals, S.A.
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CLINICAL_TRIALS trial_result · 2015-04-27Clinical Trial Update: Possible New Therapy for Advanced Cancer [Phase 1]
A Phase 1 trial investigating a new therapy for adrenocortical carcinoma conducted by INSYS Therapeutics Inc was terminated; no results are …
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CLINICAL_TRIALS withdrawal · 2015-04-22Clinical Trial Update: Treatment Study Using Bevacizumab for Patients With Adrenocortical Carcinoma [Phase 2]
A Phase 2 clinical trial of bevacizumab for adrenocortical carcinoma has been withdrawn.
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CLINICAL_TRIALS trial_result · 2014-02-21Clinical Trial Update: Gossypol Acetic Acid in Treating Patients With Recurrent, Metastatic, or Primary Adrenocortical Cancer That Cannot Be Removed By Surgery [Phase 2]
Phase 2 trial of gossypol acetic acid in patients with recurrent, metastatic, or primary adrenocortical carcinoma that cannot be surgically …
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CLINICAL_TRIALS trial_result · 2014-01-30Clinical Trial Update: Seneca Valley Virus-001 and Cyclophosphamide in Treating Young Patients With Relapsed or Refractory Neuroblastoma, Rhabdomyosarcoma, or Rare Tumors With Neuroendocrine Features [Phase 1]
Phase 1 clinical trial update for Seneca Valley Virus-001 with Cyclophosphamide in pediatric patients with relapsed/refractory neuroblastoma…
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FDA approval · 2013-11-15FDA Approved: LYSODREN — Supplemental Application (ESTEVE PHARMACEUTICALS, S.A.)
FDA approved a supplemental application for LYSODREN (mitotane) from Esteve Pharmaceuticals, S.A., related to its labeling/indication.
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CLINICAL_TRIALS trial_result · 2013-11-06Clinical Trial Update: IMC-A12 With Mitotane vs Mitotane Alone in Recurrent, Metastatic, or Primary ACC That Cannot Be Removed by Surgery [Phase 2]
A Phase 2 trial comparing IMC-A12 (cixutumumab) plus mitotane versus mitotane alone in recurrent, metastatic, or unresectable adrenocortical…
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CLINICAL_TRIALS trial_result · 2013-07-10Clinical Trial Update: Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors [Phase 2]
Phase 2 trial update evaluating the combination of chemotherapy and tamoxifen in patients with solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2012-10-05Clinical Trial Update: S9427, Suramin in Treating Patients With Stage III or Stage IV Adrenocortical Cancer Incurable by Surgery [Phase 2]
A Phase 2 trial evaluating suramin for stage III or stage IV adrenocortical carcinoma unresectable by surgery was terminated.
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CLINICAL_TRIALS trial_result · 2012-09-12Clinical Trial Update: Surgery Plus Chemotherapy (Doxorubicin, Vincristine and Etoposide), Mitotane, and Tariquidar to Treat Adrenocortical Cancer [Phase 2]
Phase 2 trial evaluating surgery plus chemotherapy (doxorubicin, vincristine, etoposide) with mitotane and tariquidar for adrenocortical car…
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CLINICAL_TRIALS trial_result · 2012-05-02Clinical Trial Update: Tumor Necrosis Factor in Patients Undergoing Surgery for Primary Cancer or Metastatic Cancer [EARLY_Phase 1]
This early-phase 1 trial evaluated tumor necrosis factor in patients undergoing surgery for various primary or metastatic cancers, and the s…
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CLINICAL_TRIALS trial_result · 2012-04-02Clinical Trial Update: Continuous Hyperthermic Peritoneal Perfusion (CHPP) With Cisplatin for Children With Peritoneal Cancer [Phase 1]
Phase 1 trial assessing continuous hyperthermic peritoneal perfusion with cisplatin in children with peritoneal cancers. The study status is…
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CLINICAL_TRIALS trial_result · 2012-02-22Clinical Trial Update: Trial With Taxotere and Cisplatin in Non-operable Adrenocortical Carcinoma [Phase 2]
Phase 2 clinical trial evaluating Taxotere (docetaxel) with cisplatin in non-operable adrenocortical carcinoma has completed.
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: Combination Chemotherapy With Suramin Plus Doxorubicin in Treating Patients With Advanced Solid Tumors [Phase 1]
A Phase 1 trial evaluating the combination of suramin and doxorubicin in adults with advanced solid tumors, including adrenocortical carcino…