Adrenocortical Carcinoma
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma [Phase 1]
A Phase 1 clinical trial is evaluating preoperative radiation therapy for participants with resectable recurrent adrenocortical carcinoma an…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Study of Radiotherapy and Pembrolizumab in People With Adrenocortical Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating the combination of radiotherapy and pembrolizumab for Adrenocortical Carcinoma, currently recruiting.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Testing the Addition of an Anti-Cancer Drug, Cabozantinib to the Immunotherapy Drug Cemiplimab (REGN2810), in Adolescents and Adults With Advanced Adrenocortical Cancer [Phase 2]
Phase 2 clinical trial evaluating the addition of cabozantinib to cemiplimab for adolescents and adults with advanced adrenocortical carcino…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001) [NA]
A clinical trial update shows ongoing recruitment for an individualized mRNA neoantigen vaccine, mRNA-0523-L001, to treat several advanced e…
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: Mitotane With or Without Cisplatin and Etoposide After Surgery in Treating Patients With Stage I-III Adrenocortical Cancer With High Risk of Recurrence [Phase 3]
Phase 3 trial update evaluating mitotane with or without cisplatin and etoposide after surgery in patients with Stage I-III adrenocortical c…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors [Phase 1]
First-in-human Phase 1 trial update of the antibody-drug conjugate ADCT-701 in patients with neuroendocrine tumors, neuroendocrine carcinoma…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Positioning of Molecular Markers in Clinical Routine for the Management of Patients With Adrenal Cancers/Tumors (COMETE-CARE) [NA]
The COMETE-CARE study is a clinical trial evaluating how molecular markers may guide routine management of adrenal cancers/tumors. The study…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Optimal Methods of Disease Progression and Survival Analysis in Children and Adults Patients With Adrenocortical Cancer (ACC)
A clinical trial update focusing on optimal methods for assessing disease progression and survival in children and adults with adrenocortica…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma [Phase 2]
A Phase 2 clinical trial evaluating PDS01ADC with hepatic artery infusion pump and systemic therapy for metastatic colorectal cancer, intrah…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate Cancer [Phase 1]
A Phase 1 trial update for DS9051b in advanced or metastatic adrenocortical carcinoma and metastatic castration-resistant prostate cancer, c…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Phase II Trial of Pembrolizumab Plus Lenvatinib in Advanced Adrenal Cortical Carcinoma [Phase 2]
This clinical trial update reports a Phase II study evaluating the combination of pembrolizumab and lenvatinib in advanced adrenocortical ca…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Nivolumab Combined With Ipilimumab for Patients With Advanced Rare Genitourinary Tumors [Phase 2]
Status update on a Phase 2 trial of nivolumab plus ipilimumab for advanced rare genitourinary tumors; the study is currently active but not …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Characterization of the Strasbourg Cohort of Patients With Adrenal Cortex Carcinoma
A Strasbourg-based observational study is recruiting to characterize a cohort of patients with adrenocortical carcinoma.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Structured Evaluation of adRENal Tumors Discovered Incidentally - Prospectively Investigating the Testing Yield
A completed prospective study evaluating the testing yield for adrenal incidentalomas and adrenocortical carcinoma. Sponsored by University …
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)
An ongoing NCI-sponsored observational study to collect tissue samples and characterize the natural history of neuroendocrine neoplasms, inc…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: A Prospective, Randomized, Multicenter Clinical Study Comparing Adjuvant Radiotherapy Versus Observation in High-risk Localized Adrenocortical Carcinoma After Surgery. [NA]
A prospective, randomized, multicenter clinical trial to compare adjuvant radiotherapy versus observation after surgery in high-risk localiz…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: German Adrenocortical Carcinoma Registry
A German registry study for Adrenocortical Carcinoma sponsored by the University of Würzburg is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Adrenal Tumors - Pathogenesis and Therapy
This clinical trial update indicates that a study on the pathogenesis and therapy of adrenal tumors is currently recruiting, covering condit…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma
Preclinical immunotherapy program for adrenocortical carcinoma is described, with Cushing's syndrome listed as a condition; the trial status…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma [Phase 2]
Phase II study evaluating a PD-1 inhibitor in combination with apatinib and mitotane for advanced adrenocortical carcinoma; the trial is cur…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: Phase II Study of PD-1 Antibody Combined With Radiotherapy in Recurrent or Metastatic Adrenal Cortical Carcinoma [Phase 2]
A Phase II clinical trial is evaluating a PD-1 antibody in combination with radiotherapy for recurrent or metastatic adrenocortical carcinom…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Pembrolizumab in the Treatment of Advanced, Progressive Adrenocortical Carcinoma. [Phase 2]
A Phase 2 clinical trial evaluating pembrolizumab for advanced, progressive adrenocortical carcinoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: National Study of Adrenal Tumours
An update on a national study of adrenal tumours, currently enrolling by invitation and focusing on pheochromocytoma, paraganglioma, adrenoc…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Adrenal Project: Clinical and Epidemiological Characterization of Adrenocortical Carcinoma in a Brazilian Cohort
An ongoing observational study in Brazil aims to characterize adrenocortical carcinoma clinically and epidemiologically in a Brazilian cohor…
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CLINICAL_TRIALS research · 2024-08-01Clinical Trial Update: Evaluation of the Efficacy of Addition of Progesterone to Standard Chemotherapy in Adrenocortical Carcinoma (ACC) [Phase 2]
A Phase 2 clinical trial is assessing whether adding progesterone to standard chemotherapy improves outcomes in adrenocortical carcinoma, wi…