Adenocarcinoma of the Gastroesophageal Junction
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Suratadenoturev (OBP-301) in Combination With Pembrolizumab in Esophagogastric Adenocarcinoma [Phase 2]
Phase 2 trial evaluating Suratadenoturev (OBP-301) in combination with pembrolizumab for esophagogastric adenocarcinoma; recruitment is ongo…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: Adebrelimab Plus Apatinib Combined With SOX Regimen as Conversion Therapy for Gastric Cancer [Phase 2]
Phase 2 clinical trial evaluating conversion therapy for gastric cancer using the PD-1 inhibitor Adebrelimab plus Apatinib in combination wi…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers [NA]
A UCSF-led clinical trial is evaluating radiation therapy for metastatic gastrointestinal cancers, and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Expanded Access Use of DKN-01 for the Treatment of Advanced Solid Tumors
Expanded-access update for Leap Therapeutics' DKN-01 in advanced solid tumors, noting the program is no longer available and targeting multi…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: A Study on Immunotherapy Combined With Radiotherapy for Esophagogastric Junction/Gastric Adenocarcinoma [Phase 2]
Phase 2 study evaluating immunotherapy combined with radiotherapy for gastroesophageal junction and gastric adenocarcinoma; currently not re…
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CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Efficacy and Safety of IMAB362 in Combination With the EOX Regimen for CLDN18.2-positive Gastric Cancer [Phase 2]
Phase 2 trial evaluating IMAB362 (zolbetuximab) in combination with the EOX chemotherapy regimen for CLDN18.2-positive gastric, gastroesopha…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: A Prospective Study on Esophagogastrostomy by an Innovative Surgical Technique [NA]
A prospective study from Huashan Hospital is evaluating an innovative esophagogastrostomy surgical technique for gastric cancer and adenocar…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: Trial of Preoperative Therapy for Gastric and Esophagogastric Junction Adenocarcinoma [Phase 2, Phase 3]
A phase 2/3 trial of preoperative therapy for gastric and gastroesophageal junction adenocarcinoma is currently active but not recruiting. T…
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CLINICAL_TRIALS approval · 2025-01-09Clinical Trial Update: International Expanded Access Program to Provide Ramucirumab for the Treatment of Metastatic Gastric Cancer
An international expanded-access program for ramucirumab has been established to treat metastatic gastric cancer and metastatic adenocarcino…
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CLINICAL_TRIALS trial_result · 2024-11-14Clinical Trial Update: Safety and Activity of IMAB362 in Combination With Zoledronic Acid and Interleukin-2 in CLDN18.2-positive Gastric Cancer [Phase 1]
Phase 1 study assessing safety and activity of IMAB362 (zolbetuximab) in combination with zoledronic acid and interleukin-2 in CLDN18.2-posi…
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CLINICAL_TRIALS trial_result · 2024-11-12Clinical Trial Update: Chemotherapy Alone vs. Chemotherapy + Surgical Resection in Patients With Limited-metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction [Phase 3]
Phase 3 trial comparing chemotherapy alone versus chemotherapy plus surgical resection for limited-metastatic gastric cancer or gastroesopha…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Preoperative Chemotherapy vs. Chemoradiation in Esophageal / GEJ Adenocarcinoma [Phase 2, Phase 3]
This clinical trial update describes the completion of Phase 2 and Phase 3 trials comparing preoperative chemotherapy versus preoperative ch…
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: A Study of Ramucirumab Plus Pembrolizumab in Participants With Gastric or GEJ Adenocarcinoma, NSCLC, Transitional Cell Carcinoma of the Urothelium, or Biliary Tract Cancer [Phase 1]
Phase 1 trial evaluating the combination of ramucirumab and pembrolizumab in gastric/GEJ adenocarcinoma, non-small cell lung cancer, urothel…
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: Perioperative Chemo and Pembrolizumab in Gastric Cancer [Phase 2]
Phase 2 clinical trial evaluating perioperative chemotherapy with pembrolizumab for gastric cancer and gastroesophageal junction adenocarcin…
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Neoadjuvant Sintilimab Plus Chemoradiotherapy for Locally Advanced Adenocarcinoma of Esophagogastric Junction [Phase 2]
Phase 2 neoadjuvant trial evaluating sintilimab in combination with chemoradiotherapy for locally advanced adenocarcinoma of the gastroesoph…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: FOLFOX-6 Induction Chemotherapy Followed by Esophagectomy and Post-operative Chemoradiotherapy in Patients With Esophageal Adenocarcinoma [Phase 2]
Phase 2 clinical trial of FOLFOX-6 induction chemotherapy followed by esophagectomy and post-operative chemoradiotherapy for esophageal aden…
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CLINICAL_TRIALS trial_result · 2021-11-03Clinical Trial Update: PET Scan Imaging in Assessing Response in Patients With Esophageal Cancer Receiving Combination Chemotherapy [Phase 2]
Phase 2 trial evaluating PET scan imaging to assess response in patients with esophageal cancer treated with combination chemotherapy; study…
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: A Trial of ZD6474, Paclitaxel, Carboplatin, 5-Fluorouracil, and Radiation Therapy Followed by Surgery [Phase 1]
Phase 1 trial evaluating ZD6474 with paclitaxel, carboplatin, 5-fluorouracil, radiation, followed by surgery for esophageal/GEJ adenocarcino…
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CLINICAL_TRIALS trial_result · 2020-10-20Clinical Trial Update: Radiation Therapy and Chemotherapy, With or Without Cetuximab, Followed by Surgery in Treating Patients With Locally Advanced Esophageal Cancer That Can Be Removed by Surgery [Phase 3]
Phase 3 trial assessing radiation therapy and chemotherapy with or without cetuximab followed by surgery in locally advanced resectable esop…
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CLINICAL_TRIALS trial_result · 2019-10-08Clinical Trial Update: 64Cu DOTA-Trastuzumab PET/CT in Studying Patients With Gastric Cancer [NA]
Clinical trial evaluating 64Cu DOTA-Trastuzumab PET/CT imaging in patients with gastric cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-08-29Clinical Trial Update: S1201: Combination Chemo for Patients W/Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Cancer [Phase 2]
Phase 2 trial update of S1201 evaluating combination chemotherapy for advanced or metastatic esophageal, gastric, or gastroesophageal juncti…
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Second-line Treatment With Icotinib in Esophageal Carcinoma Patients With EGFR Overexpression (IHC 3+) or Positive FISH [Phase 2]
Phase 2 trial evaluating icotinib as second-line treatment in esophageal carcinoma/esophagogastric junction adenocarcinoma with EGFR overexp…
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CLINICAL_TRIALS trial_result · 2019-02-26Clinical Trial Update: Lapatinib With Carboplatin and Paclitaxel in Esophagus and Gastroesophageal Junction (GEJ) [Phase 1, Phase 2]
Phase 1/2 trial evaluating lapatinib with carboplatin and paclitaxel in esophagus and GEJ adenocarcinoma; study terminated with results post…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Capecitabine With or Without Sunitinib Malate as First-Line Therapy in Treating Patients With Metastatic Cancer of the Esophagus or Gastroesophageal Junction [Phase 2]
Phase 2 trial evaluating first-line capecitabine with or without sunitinib malate in metastatic esophageal or gastroesophageal junction aden…
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CLINICAL_TRIALS trial_result · 2018-07-02Clinical Trial Update: Oxaliplatin, Fluorouracil, Erlotinib Hydrochloride, and Radiation Therapy Before Surgery and Erlotinib Hydrochloride After Surgery in Treating Patients With Locally Advanced Cancer of the Esophagus or Gastroesophageal Junction [Phase 1]
This Phase 1 trial evaluates a multimodal approach using oxaliplatin, fluorouracil, and erlotinib with pre-surgical radiation, followed by a…