Acute Promyelocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Evaluate the Pharmacokinetics of Oral Arsenic Trioxide Solution Under Fasting and Fed Conditions, to Compare Intravenous Arsenic Trioxide, in Acute Promyelocytic Leukemia [Phase 1]
Phase 1 trial evaluated the pharmacokinetics of an oral arsenic trioxide solution under fasting and fed conditions and compared it to intrav…
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: AI-Assisted Acute Myeloid Leukemia Evaluation With the Leukemia End-to-End Analysis Platform (LEAP) Versus Clinician-Only Assessment [NA]
A completed clinical trial evaluating the LEAP AI-assisted evaluation platform versus clinician-only assessment in acute promyelocytic leuke…
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CLINICAL_TRIALS trial_result · 2025-09-23Clinical Trial Update: Venetoclax Combined With ATRA and ATO in Hyperleukocytic Acute Promyelocytic Leukemia [NA]
Clinical trial evaluating the combination of venetoclax with all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) for hyperleukocytic a…
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: Simplified Patient Care Strategy in Decreasing Early Death in Patients With Acute Promyelocytic Leukemia [NA]
Clinical trial results have been posted evaluating a simplified patient-care strategy to reduce early death in acute promyelocytic leukemia …
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CLINICAL_TRIALS trial_result · 2025-02-26Clinical Trial Update: Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia [Phase 3]
Phase 3 study NCT02688140 in newly diagnosed, high-risk Acute Promyelocytic Leukemia has completed. The entry notes the trial status as COMP…
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CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: Phase III Trial in Acute Promyelocytic Leukemia Patients [Phase 3]
Phase III clinical trial in acute promyelocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2022-10-04Clinical Trial Update: Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia [Phase 2]
Phase 2 trial investigating oral arsenic trioxide for newly diagnosed acute promyelocytic leukemia is ongoing or results not yet available.
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CLINICAL_TRIALS trial_result · 2021-12-16Clinical Trial Update: Tretinoin and Arsenic Trioxide in Treating Patients With Untreated Acute Promyelocytic Leukemia [Phase 3]
Phase 3 trial update of tretinoin and arsenic trioxide for untreated acute promyelocytic leukemia; results have been posted and the trial is…
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CLINICAL_TRIALS trial_result · 2021-11-30Clinical Trial Update: Combined Tretinoin and Arsenic Trioxide for Patients With Newly Diagnosed Acute Promyelocytic Leukemia Followed by Risk-Adapted Postremission Therapy [Phase 2]
Phase 2 trial evaluating combined tretinoin and arsenic trioxide for newly diagnosed acute promyelocytic leukemia with risk-adapted postremi…
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CLINICAL_TRIALS trial_result · 2021-09-08Clinical Trial Update: Treatment of Non-high-risk Acute Promyelocytic Leukemia (APL) With Realgar-Indigo Naturalis Formula (RIF) [Phase 3]
A Phase 3 trial evaluating Realgar-Indigo Naturalis Formula (RIF) for non-high-risk acute promyelocytic leukemia is in early status (phase 3…
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Cytarabine (Ara-C) in Children With Acute Promyelocytic Leukemia (APL) [Phase 4]
Phase 4 clinical trial update on cytarabine (Ara-C) in children with acute promyelocytic leukemia (APL) completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: AIDA 2000 Guidelines [Phase 2]
Phase 2 clinical trial update for Acute Promyelocytic Leukemia under the AIDA 2000 Guidelines.
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CLINICAL_TRIALS trial_result · 2020-06-25Clinical Trial Update: Prevention and Treatment of Differentiation Syndrome in Patients With Acute Promyelocytic Leukemia [Phase 4]
Phase 4 clinical trial update focused on prevention and treatment of differentiation syndrome in acute promyelocytic leukemia.
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CLINICAL_TRIALS trial_result · 2019-08-19Clinical Trial Update: Combined Retinoic Acid,Arsenic Trioxide and Chemo for Newly-diagnosed APL [Phase 4]
Phase 4 trial update investigating the combination of retinoic acid, arsenic trioxide, and chemotherapy for newly diagnosed acute promyelocy…
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CLINICAL_TRIALS trial_result · 2019-04-18Clinical Trial Update: All-trans Retinoic Acid, and Arsenic +/- Idarubicin [Phase 2]
Phase 2 trial evaluating all-trans retinoic acid with arsenic +/- idarubicin in acute promyelocytic leukemia has completed with results post…
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: Red Cell Transfusion Goals in Patients With Acute Leukemias [Phase 1]
Phase 1 trial completed evaluating red blood cell transfusion goals in patients with acute leukemias (acute lymphoblastic leukemia, acute my…
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CLINICAL_TRIALS trial_result · 2017-12-22Clinical Trial Update: S0535, Gemtuzumab and Combination Chemotherapy in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia [Phase 2]
Phase 2 trial update examining gemtuzumab in combination with chemotherapy for previously untreated acute promyelocytic leukemia; results po…
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CLINICAL_TRIALS trial_result · 2017-12-06Clinical Trial Update: MEK Inhibitor MEK162, Idarubicin, and Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial evaluating a MEK inhibitor (MEK162) in combination with idarubicin and cytarabine for adults with relapsed or refractory acu…
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CLINICAL_TRIALS trial_result · 2017-09-08Clinical Trial Update: Clofarabine, Cytarabine, and G-CSF in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the combination of clofarabine, cytarabine, and G-CSF in relapsed or refractory acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Promyelocytic Leukemia [Phase 3]
Phase 3 trial update evaluating combination chemotherapy in children with newly diagnosed acute promyelocytic leukemia expressing PML-RARA; …
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
A Stanford-sponsored clinical trial evaluating allogeneic transplantation for acute and chronic leukemias has been terminated.
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CLINICAL_TRIALS trial_result · 2016-01-29Clinical Trial Update: Tretinoin and Arsenic Trioxide With or Without Idarubicin in Treating Patients With Acute Promyelocytic Leukemia [Phase 2]
A Phase 2 trial evaluating tretinoin and arsenic trioxide with or without idarubicin for acute promyelocytic leukemia was terminated, and re…
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CLINICAL_TRIALS trial_result · 2015-12-04Clinical Trial Update: Romidepsin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
This Phase 2 trial updates romidepsin for relapsed or refractory acute myeloid leukemia, covering several AML subtypes defined by cytogeneti…
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CLINICAL_TRIALS trial_result · 2015-08-05Clinical Trial Update: Selumetinib in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update evaluating selumetinib in adults with recurrent or refractory acute myeloid leukemia, including AML with t(15;…
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Biomarkers in Bone Marrow Samples From Patients With Acute Promyelocytic Leukemia
A completed clinical trial update reports biomarker analyses in bone marrow samples from patients with acute promyelocytic leukemia (APL). T…