Acute Promyelocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ... [Phase 1]
Phase I trial of pexidartinib (TURALIO) in children and young adults with refractory leukemias and solid tumors including NF1-associated ple…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1]
An MD Anderson trial is evaluating PET/MRI, 18F-FDG PET/CT, and whole-body MRI to detect extramedullary myeloid leukemia in patients with ne…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Pivotal Open-label Phase 3 Clinical Study of QTX-2101 in Adult Patients With Acute Promyelocytic Leukemia [Phase 3]
This update outlines the ongoing pivotal open-label Phase 3 trial of QTX-2101 in adults with acute promyelocytic leukemia. The study is curr…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Early Use of Realgar-Indigo Naturalis Formula (RIF) Combined With All-trans Retinoic Acid (ATRA) for Treating Acute Promyelocytic Leukemia (APL). [Phase 3]
This clinical trial update indicates a Phase 3 study evaluating Realgar-Indigo Naturalis Formula (RIF) combined with all-trans retinoic acid…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301) [Phase 3]
Phase 3 trial LATITUDE/SDKARS-301 is evaluating whether oral arsenic trioxide is similar to intravenous arsenic trioxide in pharmacokinetics…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Tretinoin and Arsenic Trioxide With or Without Gemtuzumab Ozogamicin in Treating Patients With Previously Untreated Acute Promyelocytic Leukemia [Phase 2]
This is a Phase 2 trial evaluating tretinoin and arsenic trioxide with or without gemtuzumab ozogamicin in newly diagnosed acute promyelocyt…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: French Registry of First-line Treatment of Acute Promyelocytic Leukemia
French registry study documenting first-line treatment of acute promyelocytic leukemia; sponsored by Groupe Francophone des Myelodysplasies,…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Frontline Oral Arsenic Trioxide for APL [Phase 2]
A Phase 2 trial evaluating frontline oral arsenic trioxide for acute promyelocytic leukemia is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Oral Arsenic With ATRA for Newly Diagnosed Patients With Acute Promyelocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating oral arsenic in combination with all-trans retinoic acid (ATRA) for newly diagnosed acute promyelocytic le…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: Treatment of Chidamide and Venetoclax for Retinoic Acid and Arsenic Resistant Acute Promyelocytic Leukemia [Phase 2]
Phase 2 clinical trial evaluating chidamide in combination with venetoclax for retinoic acid- and arsenic-resistant acute promyelocytic leuk…
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CLINICAL_TRIALS research · 2024-08-09Clinical Trial Update: Venetoclax for Prevention of Differentiation Syndrom in Acute Promyelocytic Leukemia Patients [Phase 2, Phase 3]
A Phase 2/Phase 3 clinical trial is evaluating venetoclax to prevent differentiation syndrome in patients with acute promyelocytic leukemia,…
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CLINICAL_TRIALS research · 2024-06-10Clinical Trial Update: Evaluate the Efficacy and Safety of Interferon-α Combined With ATO in the Treatment of Arsenic-resistant APL [NA]
This clinical trial update tests the efficacy and safety of combining Interferon-α with arsenic trioxide in arsenic-resistant acute promyelo…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Optimum Induction Therapy of Low-risk APL [NA]
A clinical trial (NCT05832320) at Peking University People's Hospital is evaluating optimum oral induction therapy for low-risk acute promye…
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CLINICAL_TRIALS research · 2018-09-07Clinical Trial Update: WT1 Immunity Via DNA Fusion Gene Vaccination in Haematological Malignancies by Intramuscular Injection Followed by Intramuscular Electroporation [Phase 2]
Phase 2 clinical trial investigating WT1 DNA fusion gene vaccination with intramuscular injection and electroporation for haematological mal…
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CLINICAL_TRIALS research · 2018-04-24Clinical Trial Update: Role of Microparticles in the Coagulopathy of Acute Promyelocytic Leukemia
A clinical trial update examining the role of microparticles in the coagulopathy of acute promyelocytic leukemia.
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CLINICAL_TRIALS research · 2017-01-26Clinical Trial Update: Treatment Study for Children and Adolescents With Acute Promyelocitic Leukemia [Phase 3]
A Phase 3 clinical trial update for treatment in children and adolescents with acute promyelocytic leukemia; the current status is unknown.
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CLINICAL_TRIALS research · 2015-10-02Clinical Trial Update: Biomarkers in Tissue Samples From Patients With Acute Promyelocytic Leukemia
This document reports on a completed clinical trial that investigates biomarkers in tissue samples from patients with acute promyelocytic le…
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CLINICAL_TRIALS research · 2014-10-02Clinical Trial Update: Long-Term Quality of Life in Patients With Acute Promyelocytic Leukemia
This clinical trial update summarizes long-term quality-of-life outcomes in patients with Acute promyelocytic leukemia. The report does not …
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CLINICAL_TRIALS research · 2013-09-25Clinical Trial Update: Proteasome Inhibition in Acute Promyelocytic Leukemia [Phase 2]
A Phase 2 clinical trial is investigating proteasome inhibition for relapsed acute promyelocytic leukemia, with the current status listed as…
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CLINICAL_TRIALS research · 2013-09-20Clinical Trial Update: Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Promyelocytic Leukemia [Phase 3]
A Phase 3 clinical trial compares combination chemotherapy with or without bone marrow transplantation for acute promyelocytic leukemia; the…
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CLINICAL_TRIALS research · 2008-05-12Clinical Trial Update: Study of NRX 195183 Therapy for Patients With Relapsed or Refractory Acute Promyelocytic Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study of NRX 195183 in patients with relapsed or refractory acute promyelocytic leukemia; the…
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CLINICAL_TRIALS research · 2007-10-23Clinical Trial Update: Treatment Protocol for Relapsed Acute Promyelocytic Leukemia (APL) With Arsenic [Phase 4]
This clinical trial update describes a Phase 4 treatment protocol using arsenic trioxide for relapsed or refractory acute promyelocytic leuk…