Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Trial to Reduce Alloimmunization to Platelets (TRAP) [Phase 3]
Phase 3 trial TRAP investigating reduction of alloimmunization to platelets has completed.
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5429083 Alone or in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia [Phase 1]
This is a Phase 1 clinical trial evaluating RO5429083 alone or in combination with cytarabine in patients with acute myeloid leukemia. The s…
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CLINICAL_TRIALS trial_result · 2016-11-02Clinical Trial Update: A Study of RO5045337 in Combination With Cytarabine in Patients With Acute Myelogenous Leukemia [Phase 1]
This clinical trial update reports on a phase 1 study evaluating RO5045337 in combination with cytarabine in patients with acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2016-10-24Clinical Trial Update: Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating decitabine with or without bortezomib in older adults with acute myeloid leukemia; study completed with results pos…
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CLINICAL_TRIALS trial_result · 2016-10-13Clinical Trial Update: LBH589 Plus Decitabine for Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This Phase 1/2 clinical trial evaluated the combination of LBH589 (panobinostat) and decitabine in patients with acute myeloid leukemia or m…
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CLINICAL_TRIALS trial_result · 2016-10-12Clinical Trial Update: Treosulfan/Fludarabine/Low Dose TBI as a Preparative Regimen for Children With AML/MDS Undergoing Allo HCT [Phase 2]
This Phase 2 trial evaluates a treosulfan/fludarabine/low-dose total body irradiation preparative regimen for children with acute myeloid le…
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CLINICAL_TRIALS research · 2016-10-12Clinical Trial Update: Molecular Epidemiology of Childhood Leukemia (Aka The California Childhood Leukemia Study)
A completed status update for the California Childhood Leukemia Study, a molecular epidemiology study investigating childhood leukemia. The …
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CLINICAL_TRIALS trial_result · 2016-10-07Clinical Trial Update: Treatment of Older Adult Acute Myeloid Leukemia Patients Aged 55 to 65 Years [NA]
Clinical trial update regarding treatment for older adults with acute myeloid leukemia aged 55 to 65; the current status of the trial is unk…
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CLINICAL_TRIALS research · 2016-10-07Clinical Trial Update: Treatment of Elderly Chinese Acute Myeloid Leukemia Patients Aged 65 to 75 Years Old [NA]
An update on a clinical trial evaluating treatment in elderly Chinese patients with Acute Myeloid Leukemia aged 65 to 75; the current trial …
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FDA approval · 2016-09-29FDA Approved: AZACITIDINE — Original Application (Fresenius Kabi USA, LLC)
FDA approved Fresenius Kabi USA, LLC's azacitidine injection as an original application (ANDA) for a generic version. It is approved for the…
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Interferon for the Intervention of Molecular Relapse in t (8; 21) AML After Allo-HSCT [Phase 4]
This entry provides an update on a Phase 4 clinical trial evaluating interferon for intervention of molecular relapse in t(8;21) acute myelo…
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CLINICAL_TRIALS trial_result · 2016-09-20Clinical Trial Update: Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes [Phase 3]
This Phase 3 trial evaluated cytarabine and daunorubicin with or without gemtuzumab ozogamicin in older patients with acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Tipifarnib Versus Best Supportive Care in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 3]
A Phase 3 trial comparing tipifarnib to best supportive care in newly diagnosed acute myeloid leukemia has completed; the brief update does …
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Invasives Aspergillosis in Acute Myeloid Leukemia
A clinical trial evaluating invasive aspergillosis in patients with acute myeloid leukemia has completed.
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CLINICAL_TRIALS withdrawal · 2016-09-14Clinical Trial Update: Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis [Phase 1]
This Phase 1 trial of a combination of ruxolitinib phosphate, tacrolimus, and sirolimus to prevent acute graft-versus-host disease in patien…
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CLINICAL_TRIALS trial_result · 2016-09-14Clinical Trial Update: Transfusion in Adult Acute Myeloid Leukemia
Clinical trial NCT02899767 investigating transfusion strategies in adult acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2016-09-12Clinical Trial Update: Single Treatment With FT1050 of an Ex-vivo Modulated Umbilical Cord Blood Unit [Phase 1]
This update reports the completion of a Phase 1 trial evaluating a single treatment with FT1050, an ex-vivo modulated umbilical cord blood u…
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CLINICAL_TRIALS trial_result · 2016-09-09Clinical Trial Update: Efficacy and Safety of Panobinostat (LBH589) in Patients With Refractory de Novo or Secondary Acute Myelogenous Leukemia (AML) [Phase 2]
A Phase 2 trial evaluating panobinostat in patients with refractory de novo or secondary acute myeloid leukemia. The study reports on effica…
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CLINICAL_TRIALS research · 2016-09-09Clinical Trial Update: Infection and Tumour Antigen Cellular Therapy [Phase 1]
Phase 1 clinical trial update for infection and tumour antigen cellular therapy in acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-09-01Clinical Trial Update: Cytarabine With or Without SCH 900776 in Treating Adult Patients With Relapsed Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating cytarabine with or without SCH 900776 in adults with relapsed acute myeloid leukemia has completed, and re…
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CLINICAL_TRIALS withdrawal · 2016-09-01Clinical Trial Update: A Study Assessing tOTX015 in Combination With Azacitidine (AZA) or AZA Single Agent in Patients With Newly-diagnosed Acute Myeloid Leukemia (AML) Not Candidate for Standard Intensive Induction Therapy (SIIT) [Phase 1, Phase 2]
A Phase 1/2 study evaluating tOTX015 in combination with azacitidine or azacitidine alone in newly diagnosed acute myeloid leukemia patients…
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Study of Decitabine Alone or in Combination With Valproic Acid and All-trans Retinoic Acid in Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update evaluating decitabine alone or in combination with valproic acid and all-trans retinoic acid in adults with ac…
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CLINICAL_TRIALS trial_result · 2016-08-31Clinical Trial Update: Decitabine Followed by Donor Lymphocyte Infusion for Patients With Relapsed Acute Myeloblastic Leukemia(AML) After Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
Clinical trial investigating decitabine followed by donor lymphocyte infusion for relapse AML after allogeneic stem cell transplantation; th…
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FDA approval · 2016-08-23FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
The FDA approved a supplemental application for Vidaza (azacitidine) submitted by Celgene Corporation, updating/adding to the product's labe…
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CLINICAL_TRIALS trial_result · 2016-08-19Clinical Trial Update: Umbilical Cord Blood Transplant for Hematological Malignancies [Phase 1]
Phase 1 clinical trial evaluating umbilical cord blood transplantation for hematologic malignancies has completed enrollment and reporting.