Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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FDA approval · 2017-01-30FDA Approved: VIDAZA — Supplemental Application (Celgene Corporation)
The FDA approved a supplemental application for Vidaza (azacitidine) submitted by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Use of Ribavirin and Low Dose Ara-C to Treat Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 trial evaluating ribavirin plus low-dose cytarabine for acute myeloid leukemia has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-01-30Clinical Trial Update: Physical Conditioning and Decitabine for Newly Diagnosed AML Patients Age ≥ 60 [Phase 1]
Phase 1 trial update on decitabine with physical conditioning for newly diagnosed acute myeloid leukemia patients aged 60 and older. The stu…
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Efficacy of Gemtuzumab Ozogamycin for Patients Presenting an Acute Myeloid Leukemia (AML) With Intermediate Risk [Phase 3]
Phase 3 trial update evaluating the efficacy of gemtuzumab ozogamicin in adults with intermediate-risk acute myeloid leukemia; the study has…
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CLINICAL_TRIALS withdrawal · 2017-01-27Clinical Trial Update: Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia [Phase 1]
A Phase 1 dose-escalation study in relapsed or refractory acute myeloid leukemia and relapsed/refractory B-cell acute lymphoblastic leukemia…
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CLINICAL_TRIALS withdrawal · 2017-01-27Clinical Trial Update: A Study to Find a Safe Dose of Volasertib Given in Addition to Standard Salvage Chemotherapy in Children (Age 3 Months to Less Than 18 Years) With Acute Myeloid Leukaemia, in Whom Front-line Chemotherapy Failed [Phase 1]
A Phase 1 trial to determine a safe dose of volasertib added to salvage chemotherapy in children with acute myeloid leukemia after frontline…
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CLINICAL_TRIALS trial_result · 2017-01-25Clinical Trial Update: A Study of RO5503781 as a Single Agent or in Combination With Cytarabine in Participants With Acute Myelogenous Leukemia [Phase 1]
Phase 1 study of RO5503781 as a single agent or in combination with cytarabine in participants with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2017-01-25Clinical Trial Update: Study of SCH 900776 (MK-8776) With and Without Cytarabine in Participants With Acute Leukemias (P05247) [Phase 1]
Phase 1 study of SCH 900776 (MK-8776) with and without cytarabine in acute leukemias; the trial is terminated with posted results.
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CLINICAL_TRIALS research · 2017-01-25Clinical Trial Update: Study to Evaluate the Effect of Aprepitant in Children and Adolescents Receiving AML Remission Induction Chemotherapy [Phase 3]
A Phase 3 clinical trial evaluates aprepitant for preventing chemotherapy-induced vomiting in children and adolescents undergoing remission …
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CLINICAL_TRIALS trial_result · 2017-01-23Clinical Trial Update: Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT [Phase 1, Phase 2]
The document reports the completion of a Phase 1/2 trial evaluating a TCR alpha-beta depleted graft in pediatric patients with acute lymphob…
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CLINICAL_TRIALS trial_result · 2017-01-20Clinical Trial Update: Decitabine Versus Conventional Chemotherapy for Maintenance Therapy of Acute Myeloid Leukemia With t(8;21) [Phase 4]
Phase 4 clinical trial update comparing Decitabine maintenance therapy to conventional chemotherapy in patients with acute myeloid leukemia …
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CLINICAL_TRIALS trial_result · 2017-01-19Clinical Trial Update: DTGM Fusion Protein in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial of DTGM Fusion Protein in patients with recurrent or refractory acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2017-01-18Clinical Trial Update: Sorafenib In Relapse of FMS-like Tyrosine Kinase 3 (FLT3)-Internal Tandem Duplication (ITD) AML Trial
A clinical trial evaluating sorafenib for relapsed FLT3-ITD acute myeloid leukemia has completed.
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CLINICAL_TRIALS research · 2017-01-12Clinical Trial Update: ED-TBI Followed By Allogeneic Stem Cell Transplantation For The Treatment Of Refractory AML And Advanced MDS [Phase 2]
Phase 2 trial evaluating external total body irradiation followed by allogeneic stem cell transplantation for refractory acute leukemia and …
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CLINICAL_TRIALS research · 2017-01-10Clinical Trial Update: Research Study for Treatment of Children and Adolescents With Acute Myeloid Leukaemia 0-18 Years [Phase 3]
Phase 3 clinical trial investigating treatments for children and adolescents (0-18 years) with acute myeloid leukemia. The current trial sta…
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CLINICAL_TRIALS withdrawal · 2017-01-10Clinical Trial Update: Telomere and Telomerase
A clinical trial investigating telomere and telomerase in acute myeloid leukemia was withdrawn.
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CLINICAL_TRIALS trial_result · 2017-01-06Clinical Trial Update: Physical Activity as Self-Management Approach to Improve Health Outcomes in AML [NA]
A completed clinical trial evaluated physical activity as a self-management approach to improve health outcomes in acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2016-12-29Clinical Trial Update: Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome [Phase 2]
A Phase 2 trial evaluating CPI-613 for refractory or relapsed Acute Myeloid Leukemia and Myelodysplastic Syndrome has been withdrawn.
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CLINICAL_TRIALS trial_result · 2016-12-28Clinical Trial Update: Biomarker To Evaluate Protein Profiles of Neutropenic Fever/Infection With Acute or Chronic Leukemias
This completed clinical trial investigates protein biomarker profiles in neutropenic fever/infection among patients with acute or chronic le…
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CLINICAL_TRIALS trial_result · 2016-12-13Clinical Trial Update: Assessment of Body, Liver and Labile Plasma Iron and Their Association With Outcome and Immunological Recovery in Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) Patients Undergoing Allogeneic Stem Cell Transplantation - ALLIVE (ALLogeneic Iron inVEstigators) Observational Trial
An observational study (ALLIVE) completed that evaluated body, liver, and labile plasma iron metrics and their associations with clinical ou…
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Safety Study of Thioridazine in Combination With Cytarabine to Treat Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A completed Phase 1 safety trial evaluated the combination of thioridazine and cytarabine in relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2016-12-07Clinical Trial Update: Decitabine in Combination With Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia [Phase 3]
Phase 3 clinical trial evaluating decitabine in combination with low-dose cytarabine for elderly patients with acute myeloid leukemia; curre…
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy in CD7 Positive Leukemia and Lymphoma [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating CAR-pNK cell immunotherapy for CD7-positive leukemias and lymphomas. The available snippet does n…
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CLINICAL_TRIALS research · 2016-12-06Clinical Trial Update: CAR-pNK Cell Immunotherapy for Relapsed/Refractory CD33+ AML [Phase 1, Phase 2]
This entry reports a clinical trial update for CAR-pNK cell immunotherapy in relapsed/refractory CD33+ acute myeloid leukemia. The trial spa…
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CLINICAL_TRIALS trial_result · 2016-11-08Clinical Trial Update: Study of Molecular and Genetic Abnormalities in Patients With Myeloid Neoplasms [Phase 2]
Phase 2 clinical trial update studying molecular and genetic abnormalities in patients with myeloid neoplasms, including Acute myeloid leuke…