Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-04-25Clinical Trial Update: Treatment of Relapsed or Refractory Acute Myeloblastic Leukemia [Phase 1, Phase 2]
This document reports an update on a Phase 1/2 clinical trial evaluating treatment for relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS withdrawal · 2017-04-20Clinical Trial Update: Open Label Study of Sargramostim Among Patients Receiving Myelosuppressive Induction Chemotherapy for Acute Myelogenous Leukemia [Phase 2]
Open-label Phase 2 trial of sargramostim in patients receiving myelosuppressive induction chemotherapy for acute myeloid leukemia has been w…
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: All-Trans Retinoic Acid in Combination With Standard Induction and Consolidation Therapy in Older Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 3]
This document reports on a Phase 3 trial evaluating all-trans retinoic acid added to standard induction and consolidation therapy in older p…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: MS-275 and GM-CSF in Treating Patients With Myelodysplastic Syndrome and/or Relapsed or Refractory Acute Myeloid Leukemia or Acute Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating MS-275 (entinostat) in combination with GM-CSF in adults with myelodysplastic syndromes and/or relapsed or refracto…
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CLINICAL_TRIALS trial_result · 2017-04-17Clinical Trial Update: Treatment for Relapsed/Refractory AML Based on a High Throughput Drug Sensitivity Assay [NA]
Clinical trial update on using a high-throughput drug sensitivity assay to guide treatment for relapsed/refractory acute myeloid leukemia.
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CLINICAL_TRIALS research · 2017-04-13Clinical Trial Update: B7.1/IL-2 Leukaemia Cell Vaccine for Non-Transplant AML RFUSIN2-AML2 (NTX) [Phase 1]
Phase 1 clinical trial update of a B7.1/IL-2 leukemia cell vaccine for non-transplant acute myeloid leukemia and myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia
This clinical trial update reports results from a completed study evaluating saline-washed platelet and red cell transfusions in adults with…
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CLINICAL_TRIALS trial_result · 2017-04-07Clinical Trial Update: A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs [Phase 2]
A Phase 2 safety and tolerability trial evaluating CDX-301 with or without plerixafor for stem cell mobilization in matched related donor/re…
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CLINICAL_TRIALS trial_result · 2017-04-06Clinical Trial Update: Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders [Phase 2]
Phase 2 clinical trial evaluating nonmyeloablative allogeneic stem cell transplantation for various hematologic disorders has completed.
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CLINICAL_TRIALS withdrawal · 2017-04-05Clinical Trial Update: A Study of Volasertib Plus Induction Chemotherapy for Acute Myeloid Leukemia [Phase 1]
Phase 1 study of volasertib plus induction chemotherapy for acute myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Bortezomib in Treating Patients With High-Risk Acute Myeloid Leukemia in Remission [Phase 2]
Phase 2 clinical trial update evaluating bortezomib for high-risk acute myeloid leukemia in remission; the study was terminated with results…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: Chemosensitization With Plerixafor Plus G-CSF in Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 trial evaluating chemosensitization with plerixafor plus G-CSF in acute myeloid leukemia has completed, with results posted in 2…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: High Dose Donor Hematopoietic Stem Cell Infusion for Relapsed/Refractory AML [Phase 1, Phase 2]
This clinical trial update covers high-dose donor hematopoietic stem cell infusion being evaluated for relapsed or refractory acute myeloid …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Decitabine Followed by Idarubicin and Cytarabine in Treating Patients With Relapsed or Refractory AML and MDS [Phase 2]
Phase 2 clinical trial evaluated a sequence of decitabine followed by idarubicin and cytarabine in adults with relapsed or refractory acute …
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CLINICAL_TRIALS trial_result · 2017-03-31Clinical Trial Update: Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies [NA]
A terminated clinical trial evaluated mobilizing donor peripheral blood stem cells with plerixafor and filgrastim before donor transplant in…
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CLINICAL_TRIALS trial_result · 2017-03-30Clinical Trial Update: Safety Assessment of Two Schedules of Intravenous Infusions of SNS-595 for the Treatment of Hematologic Malignancies [Phase 1]
Phase 1 clinical trial update describing safety assessments for two infusion schedules of SNS-595 in patients with hematologic malignancies.…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Trial of Pimasertib in Hematological Malignancies [Phase 2]
Phase 2 trial of pimasertib in acute myeloid leukemia and other hematologic neoplasms was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Biological Therapy in Treating Patients With Advanced Myelodysplastic Syndrome, Acute or Chronic Myeloid Leukemia, or Acute Lymphoblastic Leukemia Who Are Undergoing Stem Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial update reports completion of a study evaluating an investigational biological therapy in adults with advanced mye…
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CLINICAL_TRIALS trial_result · 2017-03-29Clinical Trial Update: Granulocyte-colony Stimulating Factor (G-CSF) and Plerixafor Plus Sorafenib for Acute Myelogenous Leukemia (AML) With FLT3 Mutations [Phase 1]
Phase 1 trial evaluating the combination of filgrastim, plerixafor, and sorafenib in FLT3-mutated acute myeloid leukemia; the study has comp…
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CLINICAL_TRIALS trial_result · 2017-03-22Clinical Trial Update: Sorafenib Maintenance Therapy for Patients With AML After Allogeneic Stem Cell Transplant [Phase 1]
Phase 1 results evaluating sorafenib as maintenance therapy in patients with acute myeloid leukemia after allogeneic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2017-03-17Clinical Trial Update: Use of Hyperbaric Oxygen Therapy to Improve Umbilical Cord Blood Stem Cell Homing and Subsequent Engraftment [NA]
Clinical trial results posted on using hyperbaric oxygen therapy to improve umbilical cord blood stem cell homing and engraftment in patient…
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Reduced Intensity Donor Peripheral Blood Stem Cell Transplant in Treating Patients With De Novo or Secondary Acute Myeloid Leukemia in Remission [Phase 2]
Phase 2 clinical trial evaluating reduced intensity donor peripheral blood stem cell transplantation in patients with de novo or secondary a…
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CLINICAL_TRIALS trial_result · 2017-03-16Clinical Trial Update: Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies [Phase 2]
Phase 2 trial evaluating alemtuzumab, fludarabine phosphate, and low-dose total body irradiation as a conditioning regimen before donor stem…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Prophylaxis Trial of Posaconazole Versus Standard Azole Therapy for Neutropenic Patients (Study P01899) [Phase 3]
This Phase 3 trial comparing posaconazole prophylaxis against standard azole therapy in neutropenic patients has completed. It includes pati…
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CLINICAL_TRIALS trial_result · 2017-03-10Clinical Trial Update: Ixazomib (MLN9708) in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update of ixazomib in relapsed or refractory acute myeloid leukemia has been terminated; results were posted previous…