Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Azacitidine in Treating Patients With Relapsed Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, or Acute Myeloid Leukemia Who Have Undergone Stem Cell Transplant [Phase 2]
Phase 2 trial of azacitidine in patients with relapsed myelodysplastic syndromes, chronic myelomonocytic leukemia, or acute myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2017-05-24Clinical Trial Update: Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer [NA]
Clinical trial update reports results of a conditioning regimen using fludarabine and total-body irradiation followed by donor stem cell tra…
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Biomarkers in Blood Samples From Patients With Acute Myeloid Leukemia
Clinical trial update describing biomarker analyses in blood samples from patients with acute myeloid leukemia; the study is completed.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating cyclophosphamide as GVHD prophylaxis after allogeneic peripheral blood stem cell transplantation in patients with h…
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CLINICAL_TRIALS research · 2017-05-19Clinical Trial Update: Studying Tissue Samples to Learn More About Drug Resistance in Patients With Acute Myeloid Leukemia
A completed clinical trial update describing a study that analyzes tissue samples from acute myeloid leukemia patients to learn more about d…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Haploidentical Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancer [Phase 2]
Phase 2 trial evaluating haploidentical donor bone marrow transplantation in patients with high-risk hematologic cancers; results completed …
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Biomarkers in Bone Marrow Samples From Patients With Acute Myeloid Leukemia
This is a completed clinical trial update focusing on biomarkers in bone marrow from patients with acute myeloid leukemia. The study is spon…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Biomarker Study of Chemotherapy Resistance and Outcomes in Samples From Older Patients With Acute Myeloid Leukemia
This update summarizes a biomarker study assessing chemotherapy resistance and outcomes in samples from older adults with acute myeloid leuk…
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CLINICAL_TRIALS trial_result · 2017-05-17Clinical Trial Update: Biomarkers in Bone Marrow and Blood Samples From Older Patients With Acute Myeloid Leukemia Treated With Cytarabine-Based Therapy
Biomarker study analyzing bone marrow and blood samples from older adults with acute myeloid leukemia treated with cytarabine-based therapy;…
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CLINICAL_TRIALS research · 2017-05-17Clinical Trial Update: Alternative Splicing and Leukemia Initiating Cells
An update on a clinical trial investigating how alternative splicing influences leukemia-initiating cells in acute myeloid leukemia. The cur…
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: Transfusional Iron Overload Among Leukemia Survivors
A completed study examining the occurrence and implications of transfusional iron overload in survivors of acute lymphoblastic leukemia and …
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Clofarabine and Cytarabine in Treating Patients With Acute Myeloid Leukemia With Minimal Residual Disease [Phase 2]
Phase 2 study of the combination of clofarabine and cytarabine in adults with acute myeloid leukemia across various cytogenetic subtypes and…
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CLINICAL_TRIALS trial_result · 2017-05-12Clinical Trial Update: Safety and Tolerability of HSC835 in Patients With Hematological Malignancies [Phase 1, Phase 2]
Phase 1/2 trial assessing safety and tolerability of HSC835 in patients with various hematologic malignancies completed with results posted …
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CLINICAL_TRIALS research · 2017-05-12Clinical Trial Update: Early Tapering of Immunosuppressive Agents to Immunomodulation to Improve Survival of AML Patients [Phase 4]
Clinical trial update on a Phase 4 study evaluating early tapering of immunosuppressive agents to modulate the immune system and potentially…
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Haploidentical Allogeneic Transplant With Post-transplant Infusion of Regulatory T-cells [Phase 1, Phase 2]
A terminated Phase 1/2 clinical trial evaluated haploidentical allogeneic transplantation with post-transplant regulatory T-cell infusion in…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Study of Vosaroxin or Placebo in Combination With Cytarabine in Patients With First Relapsed or Refractory AML [Phase 3]
Phase 3 trial evaluating vosaroxin with cytarabine vs placebo with cytarabine in patients with first relapsed or refractory acute myeloid le…
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CLINICAL_TRIALS withdrawal · 2017-05-09Clinical Trial Update: Decitabine and Vaccine Therapy for Patients With Relapsed AML Following Allogeneic Stem Cell Transplantation [Phase 1]
A Phase 1 study of Decitabine combined with a vaccine therapy for relapsed acute myeloid leukemia after allogeneic stem cell transplantation…
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CLINICAL_TRIALS trial_result · 2017-05-04Clinical Trial Update: Pentostatin and Lymphocyte Infusion in Preventing Graft Rejection in Patients Who Have Undergone Donor Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating pentostatin and lymphocyte infusion to prevent graft rejection after donor stem cell transplantation—compl…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Plerixafor and Sargramostim (GM-CSF) for Mobilization of Allogeneic Sibling Donors [Phase 2]
Phase 2 clinical trial evaluating the combination of plerixafor and GM-CSF (sargramostim) for mobilizing hematopoietic stem cells from allog…
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CLINICAL_TRIALS withdrawal · 2017-05-03Clinical Trial Update: Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 trial of the Wee1 inhibitor AZD1775 (adavosertib) with combination chemotherapy for relapsed or refractory acute myeloid leukemia …
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FDA approval · 2017-04-28FDA Approved: RYDAPT — Original Application (Novartis Pharmaceuticals Corporation)
FDA approved RYDAPT (midostaurin) under its original application for an indication in adults with acute myeloid leukemia with FLT3 mutation,…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission [Phase 2]
A Phase 2 trial evaluating conditioning with fludarabine and busulfan followed by allogeneic stem cell transplantation in older adults with …
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Lithium Carbonate and Tretinoin in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial assessing the combination of lithium carbonate and tretinoin in adults with relapsed or refractory acute myeloid leukemia has …
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CLINICAL_TRIALS trial_result · 2017-04-27Clinical Trial Update: Dual Energy CT vs Standard Triple Phase CT-A Randomised Control Trial [NA]
This entry notes a completed randomized trial comparing Dual Energy CT to Standard Triple Phase CT Angiography. The study involved patients …
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CLINICAL_TRIALS research · 2017-04-26Clinical Trial Update: DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia
This completed clinical trial updates DNA analysis of bone marrow and blood samples from young patients with acute myeloid leukemia or acute…