Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-03Clinical Trial Update: A Phase I/II Trial of the MUC1 Inhibitor, GO-203-2C in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This clinical trials update covers a Phase I/II study of the MUC1 inhibitor GO-203-2C in adults with relapsed or refractory acute myeloid le…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Phase1b/2 Trial Of AZA + APG1252 In Patients With High-Risk AML [Phase 1, Phase 2]
Phase 1b/2 clinical trial evaluating azacitidine (AZA) in combination with APG1252 for high-risk acute myeloid leukemia; the study is not ye…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Clinical Study of Venetoclax Combined With CACAG Regimen in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia [Phase 2]
Phase 2 study evaluating venetoclax in combination with the CACAG regimen for relapsed/refractory acute myeloid leukemia is currently recrui…
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CLINICAL_TRIALS other · 2026-04-02Clinical Trial Update: Oral Decitabine Plus Ivosidenib as First Line for Older/Unfit Adult AML Patients [Phase 2]
A Phase 2 study is evaluating the combination of oral decitabine and ivosidenib as first-line therapy for older or unfit adults with gene-mu…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Exploratory Study of Venetoclax, Homoharringtonine, Azacitidine Plus G-CSF for Newly Diagnosed AML (VHAG) [Phase 2]
An exploratory Phase 2 study evaluating VHAG (venetoclax, homoharringtonine, azacitidine, plus G-CSF) for newly diagnosed acute myeloid leuk…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood [Phase 1, Phase 2]
This ClinicalTrials.gov update describes a Phase 1/Phase 2 trial evaluating the safety and efficacy of quizartinib in children and young adu…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Efficacy and Safety of Lisafotoclax Plus Decitabine and Homoharringtonine in Venetoclax/Azacitidine Pretreated AML Patients [Phase 2]
Phase 2 trial evaluating lisafotoclax in combination with decitabine and omacetaxine mepesuccinate (homoharringtonine) for acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: A Study of GDX012 in Adults With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
The clinical trial update reports termination of a Phase 1/2 study of GDX012 in adults with relapsed or refractory acute myeloid leukemia.
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Immune Profile of Acute Myeloid Leukemia Patients Receiving Azacitidine Plus Venetoclax Induction Chemotherapy
A clinical trial update notes an ongoing study evaluating the immune profile of acute myeloid leukemia patients receiving azacitidine plus v…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: BCL2i CLAG-M in R/R Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial is evaluating a BCL-2 inhibitor in combination with the CLAG-M regimen for relapsed or refractory acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 study of C6 Ceramide NanoLiposome (CNL) in relapsed/refractory acute myeloid leukemia; the trial is currently recruiting.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML [Phase 3]
A Phase 3 clinical trial compares quizartinib plus chemotherapy to placebo plus chemotherapy in newly diagnosed FLT3-ITD negative acute myel…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Decisional Intervention for Older Adults With Acute Myeloid Leukemia and Their Caregivers [NA]
University of Rochester is conducting a clinical trial evaluating a decisional intervention for older adults with acute myeloid leukemia and…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) [Phase 1]
Phase 1 clinical trial of CD123-directed T-cell therapy for acute myeloid leukemia and related hematologic diseases is currently recruiting …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating the safety, tolerability, and antileukemic activity of Debio 1562M in adul…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Study to Evaluate S227928 as a Single Agent and in Combination With Venetoclax in Patients With R/R AML, MDS/AML, or CMML [Phase 1, Phase 2]
Clinical trial update for S227928 as a single agent and in combination with Venetoclax in relapsed/refractory AML, MDS/AML, and CMML shows t…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Digital PCR of CHIP and MR for MRD Monitoring After Allo-HSCT in AML
The trial tests digital PCR methods for monitoring minimal residual disease after allogeneic hematopoietic stem cell transplantation in acut…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Efficacy and Pharmacogenomics of Cladribine Based Salvage Chemotherapy in Patients With Relapse/Refractory and Secondary Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 salvage chemotherapy trial using cladribine in relapsed/refractory and high-risk myeloid diseases (acute myeloid leukemia and myel…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: A Phase I Open-Label Dose Escalation Study of Intravenous INKmune In Patients With MDS or AML [Phase 1]
A Phase I open-label dose-escalation study of intravenous INKmune in patients with myelodysplastic syndromes or acute myeloid leukemia was t…
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant [Phase 1]
Phase 1 trial of intensity-modulated total marrow irradiation with fludarabine phosphate and melphalan for relapsed hematologic cancers unde…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 trial evaluating a multi-agent regimen of fludarabine phosphate, cytarabine, filgrastim-sndz, gemtuzumab ozogamicin, and idarubicin …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Ruxolitinib + Allogeneic Stem Cell Transplantation in AML [Phase 2]
A Phase 2 trial assesses combining ruxolitinib with allogeneic stem cell transplantation for acute myeloid leukemia, including AML in remiss…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant [Phase 1]
Phase 1 clinical trial evaluating CMV-MVA Triplex Vaccine to enhance CMV-specific immunity and prevent CMV viremia in patients undergoing ha…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia [Phase 1]
Phase 1 study to identify the highest dose of Revumenib (SNDX-5613) after hematopoietic stem cell transplant in children with acute lymphobl…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: CPX-351 vs Intensive Chemotherapy in Patients With de Novo Intermediate or Adverse Risk AML Stratified by Genomics [Phase 2]
This Phase 2 clinical trial compares CPX-351 to intensive chemotherapy in adults with de novo intermediate- or adverse-risk acute myeloid le…