Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-01-14Clinical Trial Update: SGI-110 in Adults With Untreated Acute Myeloid Leukemia (AML), Not Considered Candidates for Intensive Remission Induction [Phase 3]
Phase 3 clinical trial update on SGI-110 (guadecitabine) in adults with untreated acute myeloid leukemia who are not candidates for intensiv…
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor [Phase 2]
Phase 2 trial evaluating two doses of ATIR101 (T-lymphocyte enriched, host alloreactive T-cell depleted) in hematologic malignancy patients …
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CLINICAL_TRIALS trial_result · 2021-01-12Clinical Trial Update: Safety and Efficacy of Donor T-lymphocytes Depleted ex Vivo of Host Alloreactive T-cells (ATIR) in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor [Phase 2]
Phase 2 trial update on ATIR, donor T-lymphocytes depleted ex vivo of host alloreactive T-cells, in patients with hematologic malignancies p…
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CLINICAL_TRIALS trial_result · 2020-12-31Clinical Trial Update: Trial Evaluating Induction Therapy With Idarubicin and Etoposide Plus Sequential or Concurrent Azacitidine and Maintenance Therapy With Azacitidine [Phase 2]
Phase 2 trial evaluating induction therapy with idarubicin and etoposide followed by sequential or concurrent azacitidine and maintenance az…
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CLINICAL_TRIALS trial_result · 2020-12-22Clinical Trial Update: Dec+Flu+Bu Conditioning Regimen for Elderly AML in CR Undergoing Allo-HSCT [Phase 2, Phase 3]
Phase 2/3 clinical trial update on a Dec+Flu+Bu conditioning regimen for elderly AML patients undergoing allogeneic hematopoietic stem cell …
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Efficacy and Safety of Cladribine in Combination With CAG in Newly Diagnosed Unfit Patients With AML [Phase 2]
Phase 2 trial update evaluating cladribine in combination with CAG for efficacy and safety in newly diagnosed unfit patients with acute myel…
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CLINICAL_TRIALS trial_result · 2020-12-10Clinical Trial Update: Combination of Quizartinib and Omacetaxine Mepesuccinate for AML Carrying FLT3-ITD [Phase 2]
Phase 2 trial update investigating the combination of Quizartinib and Omacetaxine Mepesuccinate for AML with FLT3-ITD mutation.
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Pharmacokinetics of Micafungin Given Twice Weekly Intravenously Compared to Micafungin Given Daily to Patients at Risk for Developing an Invasive Fungal Disease [Phase 2]
Phase 2 trial update comparing twice-weekly intravenous micafungin pharmacokinetics to daily dosing in patients at risk for invasive fungal …
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Clofarabine Combinations in Relapsed/Refractory Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS) and Myeloid Blast Phase Chronic Myeloid Leukemia (CML) [Phase 2]
Phase 2 trial update of clo farabine combinations in relapsed/refractory AML and MDS (and myeloid blast phase CML) with results posted.
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CLINICAL_TRIALS trial_result · 2020-11-27Clinical Trial Update: QUILT-3.033: Haplo NK With SQ ALT-803 for Adults With Relapsed or Refractory AML [Phase 2]
Phase 2 trial update for haploidentical NK cells with ALT-803 in adults with relapsed or refractory acute myeloid leukemia has completed wit…
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FDA label_change · 2020-11-24FDA Approved: IDHIFA — Supplemental Application (Celgene Corporation)
The FDA lists a supplemental labeling application for IDHIFA (enasidenib) by Celgene Corporation.
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CLINICAL_TRIALS trial_result · 2020-11-24Clinical Trial Update: Eltrombopag Olamine in Improving Platelet Recovery in Older Patients With Acute Myeloid Leukemia Undergoing Chemotherapy [Phase 2]
Phase 2 trial evaluating eltrombopag olamine to improve platelet recovery in older patients with acute myeloid leukemia undergoing chemother…
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CLINICAL_TRIALS research · 2020-11-23Clinical Trial Update: GVHD Prophylaxis With Post-transplantation Bendamustine in Refractory Leukemia [Phase 1, Phase 2]
Clinical trial exploring bendamustine as GVHD prophylaxis after transplantation in refractory leukemia, reported in Phase 1/Phase 2.
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CLINICAL_TRIALS trial_result · 2020-11-20Clinical Trial Update: Personalized Targeted Preparative Regimen Before T-depleted Allogeneic HSCT in Children With Chemoresistent Acute Leukemias [Phase 3]
Phase 3 trial evaluating a personalized preparative regimen prior to T-depleted allogeneic HSCT in children with chemoresistant acute leukem…
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CLINICAL_TRIALS trial_result · 2020-11-17Clinical Trial Update: Phase II Study of Bexarotene in Patients With Acute Myeloid Leukemia [Phase 2]
Phase II study of bexarotene in Acute Myeloid Leukemia was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-11-06Clinical Trial Update: Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission [Phase 3]
Phase 3 trial results evaluating maintenance therapy with oral azacitidine plus best supportive care in adults with acute myeloid leukemia w…
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CLINICAL_TRIALS trial_result · 2020-10-29Clinical Trial Update: Pevonedistat and Azacitidine as Maintenance Therapy After Allogeneic Stem Cell Transplantation for Non-Remission AML [Phase 2]
Phase 2 trial evaluating pevonedistat plus azacitidine as maintenance therapy after allogeneic stem cell transplantation in non-remission ac…
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Study of Vosaroxin With Azacitidine in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome With Excess Blasts-2 [Phase 2]
Phase 2 trial evaluating vosaroxin with azacitidine for newly diagnosed acute myeloid leukemia or Myelodysplastic Syndrome with excess blast…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: Avelumab and Azacitidine in Treating Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial evaluating avelumab plus azacitidine for refractory or relapsed acute myeloid leukemia (AML) arising from prior myelodysplast…
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CLINICAL_TRIALS trial_result · 2020-10-22Clinical Trial Update: NK Cell Therapy Recurrent/Refractory Elderly AML [Phase 1, Phase 2]
Clinical trial update for NK cell therapy in recurrent/refractory elderly AML spanning Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Donor Lymphocyte Infusion With Azacitidine to Prevent Hematologic Malignancy Relapse After Stem Cell Transplantation [Phase 2]
Phase 2 clinical trial evaluating donor lymphocyte infusion with azacitidine to prevent relapse after stem cell transplantation.
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CLINICAL_TRIALS trial_result · 2020-10-12Clinical Trial Update: Cellular Immunotherapy for Patients With High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia [Phase 1, Phase 2]
A clinical trial evaluating cellular immunotherapy for high-risk myelodysplastic syndromes and acute myeloid leukemia in Phase 1/Phase 2.
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: Selinexor (KPT-330) in Older Patients With Relapsed AML [Phase 2]
Phase 2 clinical trial update for selinexor (KPT-330) in older patients with relapsed acute myeloid leukemia (AML) has completed with result…
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CLINICAL_TRIALS trial_result · 2020-10-05Clinical Trial Update: NK Cells as Consolidation Therapy of Acute Myeloid Leukemia in Children/Adolescents [Phase 2]
Phase 2 clinical trial assessing NK cells as consolidation therapy after initial treatment for acute myeloid leukemia in children and adoles…
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CLINICAL_TRIALS trial_result · 2020-10-01Clinical Trial Update: PH 2 ADI-PEG 20 Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial update for ADI-PEG 20 in Acute Myeloid Leukemia has completed.