Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-03-22Clinical Trial Update: Allogenic Stem Cell Transplantation for Children, Adolescents and Young Adults With Relapsed or Refractory AML [Phase 3]
Phase 3 trial assessing allogeneic stem cell transplantation for children and young adults with relapsed or refractory acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2021-03-18Clinical Trial Update: The Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plus Unrelated Cord Donor Search Versus Matched Unrelated Donor Search For AML And High-Risk MDS Patients [Phase 2]
Phase II randomized trial evaluating rapid haploidentical plus unrelated cord donor search versus matched unrelated donor search for AML and…
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FDA approval · 2021-03-17FDA Approved: DECITABINE — Supplemental Application (BluePoint Laboratories)
The FDA approved a supplemental application for decitabine by BluePoint Laboratories, authorizing a generic version of the drug.
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Standard of Care +/- Midostaurin to Prevent Relapse Post Stem Cell Transplant in Patients With FLT3-ITD Mutated AML [Phase 2]
Phase 2 trial update evaluating Standard of Care with or without Midostaurin to prevent relapse after stem cell transplant in FLT3-ITD mutat…
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CLINICAL_TRIALS trial_result · 2021-03-16Clinical Trial Update: Safety and Activity of Digoxin With Decitabine in Adult AML and MDS [Phase 1, Phase 2]
Phase 1/2 trial evaluating safety and activity of digoxin in combination with decitabine for adults with acute myeloid leukemia and myelodys…
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CLINICAL_TRIALS trial_result · 2021-03-08Clinical Trial Update: A Phase I Study of OCV-501 in Acute Myeloid Leukemia Patients [Phase 1]
Phase I trial update of OCV-501 in acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients [Phase 1]
A Phase 1 trial evaluating the combination of glasdegib (PF-04449913) with azacitidine in untreated myelodysplastic syndrome, acute myeloid …
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Phase 1 Study of SGI-110 in Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 trial update of SGI-110 in patients with acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: Outpatient Induction Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Advanced Myelodysplastic Syndrome [NA]
Clinical trial update for outpatient induction chemotherapy in adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome; trial complet…
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: Study of OCV-501 in Patients With Acute Myeloid Leukemia (AML) (Extension From Study 311-10-001) [Phase 1]
Phase 1 extension study of OCV-501 in acute myeloid leukemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-26Clinical Trial Update: Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia [Phase 2]
Phase 2 trial evaluating treosulfan, fludarabine phosphate, and total-body irradiation as conditioning before donor stem cell transplant in …
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms [Phase 1, Phase 2]
Phase 1b/2 trial assessing APR-246 plus azacitidine in TP53-mutant myeloid neoplasms completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-24Clinical Trial Update: Bortezomib and Doxil for the Treatment of Patients With Acute Myelogenous Leukemia [Phase 2]
A Phase 2 clinical trial evaluating bortezomib and Doxil for acute myeloid leukemia has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-02-21Clinical Trial Update: Haploidentical Stem Cell Transplantation for Children With Therapy Resistant Leukemia [Phase 2]
Phase 2 clinical trial evaluating haploidentical stem cell transplantation for children with therapy-resistant leukemia (ALL and AML) has be…
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FDA approval · 2021-02-10FDA Approved: IDAMYCIN PFS — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for Idamycin PFS (idarubicin hydrochloride) from Pfizer, updating the drug’s approval to include a n…
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CLINICAL_TRIALS trial_result · 2021-02-09Clinical Trial Update: Safety and Efficacy Study of Pracinostat With Azacitadine in Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 safety and efficacy study of pracinostat with azacitidine in elderly patients with newly diagnosed acute myeloid leukemia completed …
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CLINICAL_TRIALS trial_result · 2021-02-08Clinical Trial Update: A Study of ARRY-520 in Patients With Advanced Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 study of ARRY-520 in advanced myeloid leukemia and myelodysplastic syndromes has completed.
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Mitoxantrone, Etoposide, and Cytarabine (MEC) Plus Lenalidomide for Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluating MEC chemotherapy (mitoxantrone, etoposide, cytarabine) with lenalidomide for relapsed or refractory acute myeloid…
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CLINICAL_TRIALS trial_result · 2021-02-03Clinical Trial Update: Evaluate Efficacy and Safety/Tolerability Profiles of Antroquinonol in Acute Myeloid Leukemia (AML) Adult Patients [Phase 2]
Phase 2 clinical trial evaluating antroquinonol for efficacy and safety/tolerability in adults with acute myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Prospective Study of Mylotarg and G-CSF in Acute Myeloid Leukemia Treatment [Phase 2]
A Phase 2 prospective study evaluating Mylotarg (gemtuzumab ozogamicin) with G-CSF in Novo Acute Myeloid Leukemia has completed with posted …
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CLINICAL_TRIALS trial_result · 2021-01-26Clinical Trial Update: Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating busulfan, fludarabine, and clofarabine conditioning followed by allogeneic stem cell transplantation in pa…
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FDA approval · 2021-01-25FDA Approved: DECITABINE — Supplemental Application (Novadoz Pharmaceuticals LLC)
FDA approved a supplemental application for decitabine (generic) submitted by Novadoz Pharmaceuticals LLC. The approval relates to the ANDA …
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Stem Cell Transplant for Hematological Malignancy [NA]
Clinical trial update on stem cell transplantation for hematologic malignancies; status terminated with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-19Clinical Trial Update: IV Busulfan With Allo-BMT: Study for Patients With Acute Myelogenous Leukemia and Myelodysplastic Syndrome [Phase 3]
Phase 3 trial evaluating intravenous busulfan with allogeneic hematopoietic stem cell transplant for patients with myelodysplastic syndrome …
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CLINICAL_TRIALS trial_result · 2021-01-14Clinical Trial Update: CPX-351 in Treating Patients With Newly Diagnosed, High-Risk Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial of CPX-351 (Vyxeos) for newly diagnosed high-risk acute myeloid leukemia has completed with results posted.