Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-09-02Clinical Trial Update: Phase II Study of Azacitidine and Sargramostim as Maintenance Treatment for Poor-Risk AML or MDS [Phase 2]
Phase II study evaluating azacitidine with sargramostim as maintenance therapy for poor-risk AML or MDS has completed; results posted in 202…
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CLINICAL_TRIALS trial_result · 2021-08-25Clinical Trial Update: A Phase II Study of Selinexor Plus Cytarabine and Idarubicin in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) [Phase 2]
Phase II trial evaluating selinexor with cytarabine and idarubicin in relapsed/refractory acute myeloid leukemia has completed with posted r…
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: Study of Quizartinib in Japanese Patients With Newly Diagnosed Acute Myeloid Leukemia (AML) [Phase 1]
This is a Phase 1 trial evaluating quizartinib in Japanese patients with newly diagnosed acute myeloid leukemia; the study has completed and…
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CLINICAL_TRIALS trial_result · 2021-08-16Clinical Trial Update: Rollover Study for Subjects Who Have Participated in an Astellas Sponsored ASP2215 Trial [Phase 1, Phase 2]
Rollover extension study for subjects who participated in an ASP2215 (gilteritinib) trial, enrolling patients with acute myeloid leukemia; s…
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CLINICAL_TRIALS trial_result · 2021-08-11Clinical Trial Update: TET2 Mutations in Myelodysplastic Syndromes and Acute Myeloid Leukemia With Azacitidine + Ascorbic Acid [Phase 2]
Phase 2 trial updating TET2 mutation targeting with azacitidine plus ascorbic acid in myelodysplastic syndromes and acute myeloid leukemia h…
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: A Phase II Study of Pembrolizumab as Post-Remission Treatment of Patients ≥ 60 With AML [Phase 2]
Phase II study evaluating pembrolizumab as post-remission treatment in adults aged ≥60 with acute myeloid leukemia has completed accrual and…
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CLINICAL_TRIALS trial_result · 2021-08-09Clinical Trial Update: A Study Of Treatment Patterns And Clinical Outcomes In Patients Diagnosed With Acute Myeloid Leukemia Who Received Mylotarg in the Real-World
A completed real-world study evaluating treatment patterns and outcomes in acute myeloid leukemia patients who received Mylotarg (gemtuzumab…
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CLINICAL_TRIALS trial_result · 2021-08-05Clinical Trial Update: Eltrombopag in Elderly Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial of eltrombopag in elderly patients with acute myeloid leukemia has been terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-08-02Clinical Trial Update: Nalbuphine Versus Morphine for Mucositis Pain in Pediatric Cancer Patients [Phase 3]
Phase 3 clinical trial comparing nalbuphine to morphine for mucositis pain in pediatric cancer patients has completed.
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CLINICAL_TRIALS trial_result · 2021-08-02Clinical Trial Update: Study Evaluating Venetoclax in Subjects With Hematological Malignancies [Phase 1, Phase 2]
Clinical trial update for venetoclax in hematological malignancies at phases 1 and 2; study status completed.
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FDA label_change · 2021-07-26FDA Approved: IDHIFA — Supplemental Application (Celgene Corporation)
This FDA notice indicates that Celgene filed a supplemental application for IDHIFA (enasidenib mesylate), seeking changes to the approved la…
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CLINICAL_TRIALS trial_result · 2021-07-22Clinical Trial Update: An Extension Study to Determine the Safety and Anti-Leukemic Effects of Imatinib Mesylate in Adult Participants With Ph+ Leukemia [Phase 2]
An extension Phase 2 trial evaluating the safety and anti-leukemic effects of imatinib mesylate in adults with Ph+ leukemias has completed a…
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CLINICAL_TRIALS trial_result · 2021-07-15Clinical Trial Update: Alvocidib Biomarker-driven Phase 2 AML Study [Phase 2]
A Phase 2, biomarker-driven trial of alvocidib in acute myeloid leukemia was terminated; results were posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-07-06Clinical Trial Update: AML-02: Omacetaxine With Standard-of-Care Induction With Cytarabine & Idarubicin in Newly-Diagnosed AML Patients [Phase 1, Phase 2]
Phase 1/2 trial of omacetaxine with standard induction therapy (cytarabine and idarubicin) in newly diagnosed acute myeloid leukemia; study …
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CLINICAL_TRIALS trial_result · 2021-07-02Clinical Trial Update: A Dose Optimisation Study of ASLAN003 in Acute Myeloid Leukemia [Phase 2]
Phase 2 dose optimisation study of ASLAN003 in acute myeloid leukemia completed; results posted.
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FDA approval · 2021-07-02FDA Approved: DECITABINE — Original Application (Meitheal Pharmaceuticals Inc.)
FDA approved Meitheal Pharmaceuticals’ decitabine as an Original Application (ANDA), providing a generic injectable option. The approval cov…
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CLINICAL_TRIALS trial_result · 2021-07-01Clinical Trial Update: A Study of MRX2843 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial update for MRX2843 in relapsed/refractory acute myeloid leukemia (Phase 1/Phase 2) with unknown status.
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CLINICAL_TRIALS trial_result · 2021-06-30Clinical Trial Update: High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia [NA]
Clinical trial update on high-throughput drug sensitivity assay and genomics-guided treatment for relapsed or refractory acute leukemia; stu…
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FDA approval · 2021-06-25FDA Approved: DECITABINE — Supplemental Application (Mylan Institutional LLC)
FDA approved a supplemental application for decitabine (generic) submitted by Mylan Institutional LLC.
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CLINICAL_TRIALS trial_result · 2021-06-25Clinical Trial Update: A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid Leukemia [Phase 3]
Phase 3 trial evaluating intensive chemotherapy with or without glasdegib or azacitidine with or without glasdegib in patients with previous…
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CLINICAL_TRIALS trial_result · 2021-06-24Clinical Trial Update: CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma [Phase 2]
Phase 2 trial evaluating CD8+ memory T-cells as consolidative therapy after donor non-myeloablative hematopoietic cell transplant in leukemi…
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CLINICAL_TRIALS trial_result · 2021-06-23Clinical Trial Update: Laboratory-Treated (Central Memory/Naive) CD8+ T Cells in Treating Patients With Newly Diagnosed or Relapsed Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 trial evaluating laboratory-treated central memory/naive CD8+ T cells for newly diagnosed or relapsed acute myeloid leukemia; th…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine [Phase 1, Phase 2]
Phase II extension study of oral rigosertib in combination with azacitidine in myelodysplastic syndrome and related conditions has completed…
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CLINICAL_TRIALS trial_result · 2021-06-14Clinical Trial Update: Intensity Modulated Total Marrow Irradiation (IM-TMI) for Advanced Hematologic Malignancies [NA]
A completed clinical trial evaluating intensity modulated total marrow irradiation (IM-TMI) for advanced hematologic malignancies, with resu…
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CLINICAL_TRIALS trial_result · 2021-06-11Clinical Trial Update: Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation [Phase 2]
Phase 2 trial update on Total Body Irradiation with or without Total Lymphoid Irradiation and Anti-Thymocyte Globulin in non-myeloablative h…