Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Dociparstat Sodium (CX-01) Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia [Phase 2]
A Phase 2 trial assessing dociparstat sodium (CX-01) in combination with standard induction therapy for newly diagnosed acute myeloid leukem…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Haematopoietic Stem Cell Transplantation (HSCT) in Comparison to Conventional Consolidation Therapy for Patients With Acute Myeloid Leukemia (AML) (Intermediate Risk) </= 60y. After First CR [Phase 3]
A Phase 3 trial comparing hematopoietic stem cell transplantation to conventional consolidation therapy in intermediate-risk acute myeloid l…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: A Study to Evaluate the Tolerance and Efficacy of Mitoxantrone Hydrochloride Liposome Injection Combined With Cytarabine in Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Early-stage study evaluating mitoxantrone hydrochloride liposome injections with cytarabine in treatment-naive or relapsed/refractory acute …
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CLINICAL_TRIALS trial_result · 2021-10-18Clinical Trial Update: Vinblastine for Leukoreduction in Newly Diagnosed AML and Hyperleukocytosis [Phase 2]
Phase 2 trial update evaluating vinblastine for leukoreduction in newly diagnosed acute myeloid leukemia with hyperleukocytosis.
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CLINICAL_TRIALS trial_result · 2021-10-15Clinical Trial Update: GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia [Phase 2]
Phase 2 trial update for GLAD-AML using Glasdegib with two decitabine regimens in older patients with poor-risk acute myeloid leukemia; stud…
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CLINICAL_TRIALS trial_result · 2021-10-14Clinical Trial Update: HCT Versus CT in Elderly AML [Phase 3]
Phase 3 trial comparing hematopoietic cell transplantation (HCT) versus conventional therapy (CT) in elderly patients with acute myeloid leu…
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML [Phase 3]
Phase 3 trial comparing CBA vs FBA conditioning followed by allogeneic HSCT in high-risk and refractory AML is underway; current status is u…
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CLINICAL_TRIALS trial_result · 2021-10-12Clinical Trial Update: CBA Versus FBA Conditioning Followed by Haploidentical Allogeneic HSCT in Treatment of High Risk and Refractory AML [Phase 3]
A Phase 3 clinical trial comparing conditioning with cytoablative chemotherapy (CBA) versus family-blood-availability (FBA) conditioning fol…
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CLINICAL_TRIALS trial_result · 2021-10-11Clinical Trial Update: Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogenous Leukemia (AML) or High-Risk Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 trial evaluating milademetan alone and with 5-azacitidine in acute myeloid leukemia or high-risk myelodysplastic syndrome; study ter…
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CLINICAL_TRIALS trial_result · 2021-10-08Clinical Trial Update: International Randomised Phase III Clinical Trial in Children With Acute Myeloid Leukaemia [Phase 3]
Phase III international randomized trial in children with acute myeloid leukaemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2021-10-07Clinical Trial Update: Study of Idarubicin, Cytarabine, and Nivolumab in Patients With High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
Phase 1/2 trial evaluating idarubicin, cytarabine, and nivolumab in high-risk myelodysplastic syndrome and acute myeloid leukemia; study com…
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CLINICAL_TRIALS trial_result · 2021-10-06Clinical Trial Update: Study of Crenolanib in Combination With Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Activating FLT3 Mutations [Phase 3]
Phase 3 trial of crenolanib in combination with chemotherapy for relapsed or refractory acute myeloid leukemia with activating FLT3 mutation…
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CLINICAL_TRIALS trial_result · 2021-10-06Clinical Trial Update: Peginterferon Alfa-2a to Enhance Anti-leukemic Responses After Allogeneic Transplantation in Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial updates the use of peginterferon alfa-2a to enhance anti-leukemic responses after allogeneic transplantation in acute myeloid…
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia [Phase 2]
Phase 2 trial update on a targeted therapy for relapsed/refractory acute lymphoblastic leukemia and acute myeloid leukemia; trial status ter…
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Ex-vivo Primed Memory Donor Lymphocyte Infusion to Boost Anti-viral Immunity After T-cell Depleted HSCT [Phase 1, Phase 2]
Clinical trial update on ex-vivo primed memory donor lymphocyte infusion to boost antiviral immunity after T-cell depleted hematopoietic ste…
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of Max-40279-01 in Combination With Azacitidine (AZA) in Patients With Myelodysplastic Syndrome (MDS) or Relapsed/Refractory Acute Myeloid Leukemia (R/R AML) [Phase 1, Phase 2]
Phase 1/2 trial investigating Max-40279-01 with azacitidine for myelodysplastic syndrome and relapsed/refractory acute myeloid leukemia; saf…
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: A PALG Prospective Multicenter Clinical Trial to Compare the Efficacy of Two Standard Induction Therapies (DA-90 vs DAC) and Two Standard Salvage Regimens (FLAG-IDA vs CLAG-M) in AML Patients ≤ 60 Years Old [Phase 3]
A Phase 3 clinical trial comparing induction therapies DA-90 vs DAC and salvage regimens FLAG-IDA vs CLAG-M in adults up to 60 with Acute My…
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FDA approval · 2021-09-29FDA Approved: DECITABINE — Supplemental Application (Accord Healthcare Inc.)
FDA approved a supplemental application for decitabine from Accord Healthcare Inc. under an ANDA, marking an updated approval for the generi…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) [Phase 2]
Phase 2 clinical trial evaluating a conditioning regimen (busulfan, melphalan, fludarabine) with peri-transplant palifermin followed by T-ce…
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Isavuconazole in Preventing Invasive Fungal Infections in Adult Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome and Neutropenia [Phase 2]
Phase 2 trial evaluating isavuconazole for preventing invasive fungal infections in adults with newly diagnosed acute myeloid leukemia or my…
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Dasatinib, Cytarabine, and Idarubicin in Treating Patients With High-Risk Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating dasatinib, cytarabine, and idarubicin in high-risk acute myeloid leukemia was terminated; results post…
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: An Investigational Immuno-therapy Study of Ulocuplumab in Combination With Low Dose Cytarabine in Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 trial evaluating ulocuplumab plus low-dose cytarabine in newly diagnosed acute myeloid leukemia was terminated; results posted i…
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CLINICAL_TRIALS trial_result · 2021-09-14Clinical Trial Update: A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) [Phase 3]
Phase 3 trial of idasanutlin with cytarabine in relapsed/refractory AML was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-09-09Clinical Trial Update: Pinometostat and Azacitidine in Treating Patients With Relapsed, Refractory, or Newly Diagnosed Acute Myeloid Leukemia With 11q23 Rearrangement [Phase 1, Phase 2]
Phase 1/2 trial evaluating pinometostat and azacitidine in patients with 11q23/MLL rearranged AML across relapsed, refractory, or newly diag…
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: High Dose Cytarabine Followed by Pembrolizumab in Relapsed/Refractory AML [Phase 2]
Phase 2 trial evaluating high-dose cytarabine followed by pembrolizumab in relapsed/refractory acute myeloid leukemia has completed with res…