Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MB-dNPM1-TCR.1 in Relapsed/Refractory AML [Phase 1, Phase 2]
Miltenyi Biomedicine is conducting early-phase (Phase 1/2) trials of MB-dNPM1-TCR.1 for relapsed/refractory acute myeloid leukemia, and the …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Venetoclax, Azacitidine and Liposomal Mitoxantrone for Newly Diagnosed AML [NA]
Clinical trial update for a newly diagnosed acute myeloid leukemia study combining venetoclax, azacitidine, and liposomal mitoxantrone; the …
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning using treosulfan and fludara…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: The Efficacy of Allo-HSCT in ND HR-CBF-AML
A clinical trial sponsored by Ruijin Hospital is evaluating the efficacy of allogeneic hematopoietic stem cell transplantation in newly diag…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies [Phase 2]
Phase 2 study evaluating a two-step reduced-intensity conditioning approach for bone marrow transplant in adults with hematologic malignanci…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations [Phase 2]
This entry outlines a Phase 2 clinical trial testing olutasidenib in combination with a co-targeted therapy for relapsed or refractory IDH1-…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 trial update evaluating venetoclax with sequential busulfan, cladribine, and fludarabine phosphate as conditioning before donor stem…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial update evaluating a combination of venetoclax, decitabine, and cedazuridine for relapsed or refractory acute myeloi…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A Single-arm, Prospective Study of a Clad-LABU Conditioning Regimen in HSCT for R/R MDS/AML in Elderly Patients [NA]
A single-arm, prospective study evaluating a Clad-LABU conditioning regimen in hematopoietic stem cell transplantation for elderly patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene [Phase 1]
A Phase 1 clinical trial assessing adding SNDX-5613 to standard daunorubicin/cytarabine chemotherapy for newly diagnosed acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Multi-modality Imaging and Collection of Biospecimen Samples in Understanding Bone Marrow Changes in Patients With Acute Myeloid Leukemia Undergoing TBI and Chemotherapy [EARLY_Phase 1]
An early-phase study at City of Hope evaluating imaging techniques and biospecimen collection to understand bone marrow changes in patients …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia [Phase 1]
A Phase 1 clinical trial from MD Anderson tests combinations of palbociclib with sorafenib, decitabine, or dexamethasone in patients with re…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
This entry describes a Phase 2 clinical trial evaluating Orca-T after reduced-intensity or nonmyeloablative conditioning in patients with ac…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer Survivors [NA]
A clinical trial update describing a high-intensity electronic health intervention aimed at reducing learning disparities among childhood ca…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating CD45RA-depleted stem cell addback to prevent viral or fungal infections following TCRab/CD19-deplet…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Massage Impact on Sleep in Pediatric Oncology [NA]
A pediatric oncology clinical trial from Children's Hospital of Philadelphia is investigating whether massage can improve sleep for children…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update for MiRisten to treat relapsed or refractory acute myeloid leukemia. The study is currently recruiting.
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelodysplastic Syndrome (MDS) Monitored at the Nantes University Hospital
This clinical trial update describes the creation of a biocollection of patients with acute myeloid leukemia, acute lymphoblastic leukemia, …
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant [Phase 1, Phase 2]
This is a Phase 1/2 clinical trial update. It evaluates a conditioning strategy using chemotherapy, total body irradiation, and post-transpl…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: A Phase I-II Study Investigating the All-Oral Combination of the Menin Inhibitor SNDX-5613 With Decitabine/Cedazuridine (ASTX727) and Venetoclax in Acute Myeloid Leukemia (SAVE) [Phase 1, Phase 2]
A Phase I–II trial in Acute Myeloid Leukemia evaluating an all-oral combination of the menin inhibitor SNDX-5613 (revumenib) with decitabine…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
This Clinical Trial Update describes an ongoing Phase 1 study evaluating the safety and tolerability of ziftomenib in combination regimens f…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms [Phase 1]
Phase 1 study evaluating FLAG-Ida chemotherapy plus pivekimab sunirine (IMGN632) for newly diagnosed adverse-risk acute myeloid leukemia and…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating Tagraxofusp in combination with a low-intensity chemotherapy regimen for CD123-positive relapsed or re…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: ONC201 in Treating Patients With Relapsed or Refractory Acute Leukemia or High-Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating ONC201 for relapsed or refractory acute lymphoblastic leukemia, relapsed or refractory acute mye…
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FDA approval · 2026-04-13FDA Approved: VANFLYTA — Supplemental Application (Daiichi Sankyo Inc.)
FDA approved a supplemental application for VANFLYTA (quizartinib) submitted by Daiichi Sankyo Inc., resulting in changes to the drug's labe…