Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome [Phase 3]
Phase 3 trial evaluating response-based chemotherapy in younger patients with Down syndrome who have newly diagnosed acute myeloid leukemia …
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: A Dose-finding Study of CC-90009 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher-risk Myelodysplastic Syndromes [Phase 1]
A Phase 1 dose-finding study of CC-90009 in adults with relapsed or refractory acute myeloid leukemia or relapsed/refractory higher-risk mye…
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CLINICAL_TRIALS trial_result · 2025-06-11Clinical Trial Update: Clinical Trial of WBC100 Capsule in Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluates WBC100 Capsule in relapsed/refractory acute myeloid leukemia. The trial is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: CRISPR-Edited Allogeneic Anti-CLL-1 CAR-T Cell Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update of CRISPR-edited allogeneic anti-CLL-1 CAR-T cells for relapsed or refractory acute myeloid leukemia; the stud…
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CLINICAL_TRIALS withdrawal · 2025-06-11Clinical Trial Update: Optimized Dual CD33/CLL1 CAR T Cells in Subjects With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating dual CD33/CLL1 CAR T cells for patients with refractory or relapsed Acute Myeloid Leukemia has been with…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Oral-ATO for TP53-mutated Myeloid Malignancies [Phase 2]
A Phase 2 clinical trial evaluating oral arsenic trioxide for TP53-mutated myeloid malignancies, including acute myeloid leukemia and myelod…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation [Phase 1]
This Phase 1 trial update discusses orally administered AG-120 (ivosidenib) for IDH1-mutated hematologic malignancies, including relapsed/re…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: a New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia [Phase 2]
This clinical trial update describes a Phase 2 study evaluating a new treatment for newly diagnosed IDH1-mutant acute myeloid leukemia and i…
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Vaccination Against Human Papillomavirus (HPV) After Allogeneic Stem Cell Transplantation [Phase 2]
This Phase 2 trial investigates HPV vaccination in recipients of allogeneic stem cell transplantation and is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD [Phase 2]
Phase 2 clinical trial assessing selective depletion of CD45RA+ T cells from allogeneic stem cell grafts to prevent graft-versus-host diseas…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell Transplantation [Phase 2]
Phase 2 trial comparing three GVHD prophylaxis regimens in nonmyeloablative or reduced-intensity conditioning unrelated donor transplantatio…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Efficacy of HAD Induction With Intensified Cytarabine in Newly-diagnosed CEBPA Double Mutated Acute Myeloid Leukemia [Phase 2]
Phase 2 clinical trial evaluating HAD induction with intensified cytarabine in newly diagnosed CEBPA double-mutated acute myeloid leukemia; …
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Sabatolimab as a Treatment for Patients With Acute Myeloid Leukemia and Presence of Measurable Residual Disease After Allogeneic Stem Cell Transplantation. [Phase 1, Phase 2]
A clinical trial update reports that Sabatolimab was studied for acute myeloid leukemia with measurable residual disease after allogeneic st…
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CLINICAL_TRIALS withdrawal · 2025-06-03Clinical Trial Update: Daunorubicin, Cytarabine Liposomes Plus Venetoclax vs Azacitidine Plus Venetoclax in AML Patients Unfit for Intensive Chemotherapy [Phase 2]
Phase 2 trial evaluating Vyxeos (daunorubicin/cytarabine liposome) plus venetoclax versus azacitidine plus venetoclax in acute myeloid leuke…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: A Clinical Study to Evaluate the Safety and Efficacy of CLL1 and CD38 Dual-Target CAR-T Cell Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial is evaluating the safety and preliminary efficacy of a CD38 and CLL-1 dual-target CAR-T cell therapy for relapsed o…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Mitoxantrone Hydrochloride Liposome Combined With Chemotherapy in Untreated de Novo Acute Myeloid Leukemia [NA]
Clinical trial update on the use of mitoxantrone hydrochloride liposome in combination with chemotherapy for untreated de novo acute myeloid…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: Phase I/II Trial of CPX-351 + Palbociclib in Patients With Acute Myeloid Leukemia [Phase 1, Phase 2]
Results from a Phase I/II trial evaluating CPX-351 in combination with palbociclib for acute myeloid leukemia have been completed with poste…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: A Study to Assess the Safety of Xospata in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-Like Tyrosine Kinase 3 (FLT3) Mutation
A completed clinical trial assessed the safety of Xospata (gilteritinib) in patients with relapsed or refractory acute myeloid leukemia harb…
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CLINICAL_TRIALS research · 2025-05-31Clinical Trial Update: Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies [Phase 1]
This is a Phase 1, multi-institutional trial evaluating expanded multi-antigen oriented lymphocytes for very high-risk hematologic malignanc…
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CLINICAL_TRIALS trial_result · 2025-05-31Clinical Trial Update: Study of CC-96191 in Participants With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial of CC-96191 in participants with relapsed or refractory acute myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Efficacy of Idarubicin, Cytarabine and Cyclophosphamide (IAC) Regimen in Relapsed/Refractory AML [Phase 2]
A Phase 2 trial evaluated the efficacy of the idarubicin, cytarabine, and cyclophosphamide (IAC) regimen in relapsed/refractory acute myeloi…
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Efficacy and Safety of Chidamide in CBF Leukemia [Phase 1, Phase 2]
Phase 1/2 trial update reports on the efficacy and safety of chidamide in patients with acute myeloid leukemia; the study is currently activ…
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Efficacy and Safety of rhTPO for the Treatment of Thrombocytopenia After Chemotherapy in AML Patients [Phase 4]
Phase 4 clinical trial update evaluating the efficacy and safety of recombinant human thrombopoietin (rhTPO) for chemotherapy-induced thromb…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia [Phase 2, Phase 3]
Clinical trial evaluating intensive therapy combined with venetoclax for adult acute myeloid leukemia is currently active but not recruiting…