Acute Myeloid Leukemia
📧 Sign up to get email alerts when something new happens for Acute Myeloid Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS other · 2025-07-03Clinical Trial Update: Connect® Myeloid Disease Registry
The Connect Myeloid Disease Registry sponsored by Celgene has been terminated. The registry involved conditions including primary myelofibro…
-
CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Prospective Evaluation of Ivosidenib Maintenance Following Allogeneic Stem Cell Transplantation in Patients With Acute Myeloid Leukemia or High-risk Myelodysplastic Neoplasia With IDH1 (Isocitrate Dehydrogenase 1) Mutation [Phase 2]
Phase 2 trial evaluating maintenance therapy with ivosidenib after allogeneic stem cell transplantation in patients with acute myeloid leuke…
-
CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Allo HSCT Using RIC and PTCy for Hematological Diseases [Phase 2]
Phase 2 clinical trial evaluating allogeneic hematopoietic stem cell transplantation using reduced-intensity conditioning and post-transplan…
-
CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: CD33KO-HSPC Infusion Followed by CART-33 Infusion(s) for Refractory/Relapsed AML [Phase 1]
Phase 1 trial of CD33KO-HSPC infusion followed by CART-33 infusion for refractory/relapsed acute myeloid leukemia is recruiting.
-
CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: A Study to Investigate Treatment of HU and VPA, or 6-MP and VPA in Unfit AML/HR-MDS Patients [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study of combining hydroxyurea with valproic acid or 6-mercaptopurine with valproic acid in…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: HM2023-05: GTB-3650 Trike for High Risk MDS and R/R AML [Phase 1]
Phase 1 clinical trial update for GTB-3650 Trike in high-risk myeloid malignancies, including acute myeloid leukemia and myelodysplastic syn…
-
CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Study to Evaluate PK and Safety With Uproleselan Combined With Chemotherapy to Treat Chinese R/R AML Patients [Phase 1]
Phase 1 study evaluating the pharmacokinetics and safety of uproleselan in combination with chemotherapy for Chinese patients with relapsed/…
-
CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of oral LY3410738 in patients with IDH1/IDH2-mutant hematologic malignancies is currently active but not recruiting.
-
CLINICAL_TRIALS trial_result · 2025-06-27Clinical Trial Update: Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML [Phase 3]
Phase 3 trial evaluating Uproleselan in combination with chemotherapy for Relapsed/Refractory acute myeloid leukemia in Chinese patients has…
-
CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning [Phase 2]
Phase 2 trial evaluating vedolizumab with post-transplant cyclophosphamide and tacrolimus to prevent graft-versus-host disease in patients u…
-
CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Open-label Study of FT-2102 With or Without Azacitidine or Cytarabine in Patients With AML or MDS With an IDH1 Mutation [Phase 1, Phase 2]
Open-label Phase 1/2 trial of FT-2102 in IDH1-mutant acute myeloid leukemia and myelodysplastic syndrome, evaluating FT-2102 with or without…
-
CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Lentivirally Redirected CD123 Autologous T Cells in AML [Phase 1]
A Phase 1 clinical trial update evaluating lentivirally redirected CD123 autologous T cells for acute myeloid leukemia; the study is active …
-
CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Acute Myeloid Leukemia and Markers of Leukemia Stem Cells (CLL1 and CD45RA)
A clinical trial examining acute myeloid leukemia and leukemia stem cell markers CLL1 and CD45RA is currently recruiting, sponsored by Suhu …
-
CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: CART-38 in Adult AML and MM Patients [Phase 1]
Phase 1 study of CART-38 in adults with acute myeloid leukemia and multiple myeloma has been terminated; this update notes the status of the…
-
CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Feasibility of Telehealth Palliative Care and Digital Symptom Monitoring for Patients With Acute Myeloid Leukemia [NA]
A completed feasibility study evaluating telehealth palliative care and digital symptom monitoring for patients with Acute Myeloid Leukemia.
-
CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS) [Phase 2]
A Phase 2 clinical trial evaluating intensity-modulated total marrow irradiation in fully matched and partially matched allogeneic transplan…
-
CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Clinical Study of U32 in Patients With Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial of the investigational agent U32 in patients with acute myeloid leukemia is currently recruiting.
-
CLINICAL_TRIALS research · 2025-06-24Clinical Trial Update: Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders [Phase 2]
Phase 2 clinical trial evaluating myeloablative allogeneic hematopoietic stem cell transplantation from related or unrelated donors for a br…
-
CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers [Phase 2]
Phase 2 study of E7820 in people with bone marrow (myeloid) cancers, including Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Chroni…
-
CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia [Phase 1]
A Phase 1 clinical trial evaluating total marrow and lymphoid irradiation with chemotherapy before donor transplantation in patients with my…
-
CLINICAL_TRIALS withdrawal · 2025-06-22Clinical Trial Update: A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias [Phase 1]
A Phase 1 trial of JNJ-75276617 in combination with conventional chemotherapy for pediatric and young adult patients with relapsed/refractor…
-
EMA approval · 2025-06-18EMA Authorised: Phelinun (melphalan hydrochloride) — ADIENNE S.r.l. S.U.
The EMA authorised Phelinun (melphalan hydrochloride) for multiple cancers including multiple myeloma, Hodgkin lymphoma, non-Hodgkin lymphom…
-
CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Evaluation of 3 Different Doses of IV Busulfan [Phase 2]
Clinical Trial Update on a Phase 2 study evaluating three different doses of intravenous busulfan in patients with myelodysplastic syndrome …
-
CLINICAL_TRIALS trial_result · 2025-06-15Clinical Trial Update: Alpha/Beta T Cell and CD19+ B Cell Depletion in Allogeneic Stem Cell Transplantation in Patients With Malignant Diseases [Phase 2]
A Phase 2 clinical trial is testing alpha/beta T cell and CD19+ B cell depletion in allogeneic stem cell transplantation for malignant disea…
-
CLINICAL_TRIALS research · 2025-06-15Clinical Trial Update: Early Prophylactic Donor Lymphocyte Infusion After Allo-HSCT for Patients With AML [Phase 2]
This clinical trial update describes a Phase 2 study of early prophylactic donor lymphocyte infusion after allogeneic stem cell transplantat…