Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Clinical Study of Novel CAR-ITNK Cells Targeting CD70 and CLL1 for Refractory/Relapsed AML [EARLY_Phase 1]
A first-in-human early-phase trial of CAR-ITNK cells targeting CD70 and CLL1 for refractory/relapsed acute myeloid leukemia, not yet recruit…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Clinical Study of CLL-1 CAR-T in the Treatment of Children With R/R AML [EARLY_Phase 1]
This early phase 1 clinical trial evaluates a CAR-T therapy targeting CLL-1 (CLEC12A) in children with relapsed or refractory acute myeloid …
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI) in Addition to Fludarabine/Busulfan Conditioning for Allogeneic Transplantation in High Risk AML and Myelodysplastic Syndromes [Phase 2]
This is a Phase 2 study evaluating intensity-modulated total marrow irradiation added to fludarabine/busulfan conditioning for allogeneic tr…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Molecular Evaluation of AML Patients After Stem Cell Transplant to Understand Relapse Events
A clinical trial is evaluating molecular features of acute myeloid leukemia patients after stem cell transplant to understand relapse events…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission [Phase 2]
Phase 2 clinical trial evaluating azacitidine plus venetoclax as maintenance therapy in patients with acute myeloid leukemia in remission, i…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: A Study of MGD024 in Patients With Relapsed or Refractory Hematologic Malignancies [Phase 1]
MacroGenics reports a Phase 1 study of MGD024 in relapsed or refractory hematologic malignancies is currently recruiting across multiple dis…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: CART123 T Cells in Relapsed or Refractory CD123+ Hematologic Malignancies: A Dose Escalation Phase I Trial [EARLY_Phase 1]
This update describes an early-phase dose-escalation trial evaluating CART123 T cells in relapsed or refractory CD123+ hematologic malignanc…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Niclosamide in Pediatric Patients With Relapsed and Refractory AML [Phase 1]
A Phase 1 clinical trial evaluating niclosamide in pediatric patients with relapsed or refractory acute myeloid leukemia is currently recrui…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial at MD Anderson evaluating a triple combination of Quizartinib, Decitabine, and Venetoclax for untreated or relaps…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Study to Assess Adverse Events and Change in Disease Activity of Oral Venetoclax in Combination With Subcutaneous (SC) or Intravenous (IV) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Standard Induction Therapy in India [Phase 4]
Phase 4 clinical trial evaluating safety and changes in disease activity for oral venetoclax in combination with azacitidine (SC or IV) in n…
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CLINICAL_TRIALS trial_result · 2026-01-12Clinical Trial Update: Venetoclax to Augment Epigenetic Modification and Chemotherapy [Phase 1]
Phase 1 clinical trial evaluating venetoclax to augment epigenetic modification and chemotherapy in relapsed or refractory acute myeloid leu…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 clinical trial update evaluating FH-FOLR1 CAR T-cell therapy in pediatric patients with relapsed or refractory acute myeloid leukemi…
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EMA approval · 2026-01-09EMA Authorised: Onureg (azacitidine) — Bristol-Myers Squibb Pharma EEIG
The European Medicines Agency authorised Onureg (azacitidine) for acute myeloid leukemia in adults in the European Union, with Bristol-Myers…
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: A First-in-Human, JAB-8263 in Adult Patients With Advanced Tumors [Phase 1, Phase 2]
A first-in-human Phase 1/2 trial of JAB-8263 in adults with advanced tumors is currently recruiting across multiple cancer types including l…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Trial Testing Safety of IL-21 NK Cells for Induction of R/R AML [Phase 1]
Phase 1 clinical trial completed evaluating the safety of IL-21–stimulated natural killer (NK) cells for induction in relapsed/refractory ac…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Decitabine and Cedazuridine in Combination With Venetoclax for the Treatment of Patients Who Have Relapsed Acute Myeloid Leukemia After Donor Stem Cell Transplant [Phase 2]
A Phase 2 trial of decitabine/cedazuridine with venetoclax for relapsed acute myeloid leukemia after donor stem cell transplant was terminat…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation [Phase 2]
Enasidenib is being studied for relapsed or refractory IDH2-mutant acute myeloid leukemia in a Phase 2 trial. The study status is Active Not…
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CLINICAL_TRIALS trial_result · 2026-01-08Clinical Trial Update: Study of Regorafenib in Patients With Advanced Myeloid Malignancies [Phase 1]
This update reports on a Phase 1 study of regorafenib in patients with advanced myeloid malignancies, including acute myeloid leukemia; the …
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Pharmacokinetic and Safety Study of MRX-2843 in Adolescents and Adults With Relapsed/Refractory AML, ALL, or MPAL [Phase 1]
Phase 1 pharmacokinetic and safety study of MRX-2843 in adolescents and adults with relapsed/refractory acute myeloid leukemia, acute lympho…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS [Phase 1]
Phase 1 clinical trial evaluating Venetoclax in combination with intensive chemotherapy for acute myeloid leukemia and advanced myelodysplas…
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: Venetoclax and Bomedemstat in Patients With Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial is evaluating the combination of venetoclax and bomedemstat in patients with relapsed or refractory acute myeloid leukemi…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Hu8F4 in Treating Patients With Advanced Hematologic Malignancies [Phase 1]
Hu8F4 is being studied in a Phase 1 trial for multiple advanced hematologic malignancies; the study is currently active but not recruiting.
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 dose-escalation study of Minnelide for relapsed or refractory acute myeloid leukemia was terminated.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Pre-DLI or Pro-DLI in Relapsed/Refractory Myeloid Neoplasms After HSCT [NA]
This clinical trial (NCT07319793) sponsored by Peking University People's Hospital is evaluating pre-DLI or pro-DLI approaches in relapsed o…
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) [NA]
A completed clinical trial update reporting long-term outcomes of alternative donor allogeneic transplantation across multiple hematologic d…