Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Olutasidenib With Azacitidine Followed by Olutasidenib Maintenance for the Treatment of IDH1-mutated Acute Myeloid Leukemia in Patients With Prior Treatment With Venetoclax Plus a Hypomethylating Agent [Phase 2]
This Phase 2 trial evaluates olutasidenib plus azacitidine, followed by olutasidenib maintenance, for IDH1-mutated acute myeloid leukemia in…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Enasidenib and Azacitidine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia and IDH2 Gene Mutation [Phase 2]
Phase 2 trial update on enasidenib with azacitidine for recurrent or refractory acute myeloid leukemia with IDH2 mutation, currently recruit…
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CLINICAL_TRIALS trial_result · 2026-03-05Clinical Trial Update: CLAG-M or FLAG-Ida Chemotherapy and Reduced-Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia [Phase 1]
A Phase 1 trial is evaluating CLAG-M or FLAG-Ida chemotherapy with reduced-intensity conditioning donor stem cell transplant for relapsed or…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Anti-Leukemia Immune Responses After Irradiation of Extramedullary Tumors [EARLY_Phase 1]
An early-phase trial is exploring anti-leukemia immune responses after irradiation of extramedullary tumors in patients with acute myeloid l…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant [Phase 1]
A Phase 1 clinical trial update assessing olutasidenib for IDH1-mutated acute myeloid leukemia, myelodysplastic syndrome, or chronic myelomo…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Study of BL-M11D1 in Combination With Cytarabine + Daunorubicin or Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia [Phase 2, Phase 3]
This clinical trial update describes a Phase 2/Phase 3 study of BL-M11D1 in combination with cytarabine plus daunorubicin or venetoclax plus…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Pembrolizumab and Decitabine With or Without Venetoclax in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome That Is Newly-Diagnosed, Recurrent, or Refractory [Phase 1]
A Phase 1 clinical trial evaluating pembrolizumab plus decitabine, with or without venetoclax, for patients with acute myeloid leukemia or m…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Venetoclax With Combination Chemotherapy in Treating Patients With Newly Diagnosed or Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
This ongoing Phase 1/2 clinical trial is evaluating venetoclax in combination chemotherapy for newly diagnosed or relapsed/refractory acute …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant [Phase 1]
A Phase 1 clinical trial evaluating Revumenib for acute leukemia in patients after allogeneic stem cell transplant; the study is currently r…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Venetoclax Plus Hypomethylating Agents and Subcutaneous Cytarabine for CEBPA-Mutated AML [Phase 1, Phase 2]
A Phase 1/2 trial evaluating venetoclax with hypomethylating agents and subcutaneous cytarabine in patients with CEBPA-mutated acute myeloid…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors
A pediatric cancer survivor study focusing on symptom cluster heterogeneity and gut microbiota mechanisms is currently recruiting, including…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: BLAST MRD AML-1: BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1- A Randomized Phase 2 Study of Anti-PD-1 Pembrolizumab in Combination With Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia [Phase 2]
A randomized Phase 2 trial (BLAST MRD AML-1) evaluates adding pembrolizumab to intensive chemotherapy as frontline therapy for acute myeloid…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: TCRαβ-depleted Progenitor Cell Graft With Additional Memory T-cell DLI, Plus Selected Use of Blinatumomab, in Naive T-cell Depleted Haploidentical Donor Hematopoietc Cell Transplantation for Hematologic Malignancies [Phase 2]
Phase 2 clinical trial update evaluating TCRαβ-depleted progenitor cell graft with added memory T-cell donor lymphocyte infusion and selecti…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia [Phase 1]
This Phase 1 trial tests a triple-drug regimen of Revumenib, azacitidine, and venetoclax in pediatric and young adult patients with refracto…
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CLINICAL_TRIALS trial_result · 2026-03-04Clinical Trial Update: Study of Venetoclax in Combination With Decitabine in Subjects With Acute Myeloid Leukemia [Phase 1]
This document provides an update on a Phase 1 trial of venetoclax in combination with decitabine for acute myeloid leukemia, with the study …
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Phase 1b/2 Open-label, Dose-ranging Safety and Efficacy Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML) [Phase 1, Phase 2]
A Phase 1b/2 open-label study is evaluating the safety and efficacy of oral cladribine in patients with acute myeloid leukemia, with the tri…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: A Study of Gilteritinib, Venetoclax and Azacitidine as a Combined Treatment for People Newly Diagnosed With Acute Myeloid Leukemia [Phase 1, Phase 2]
Clinical trial update for a first-line combination of gilteritinib, venetoclax, and azacitidine in newly diagnosed acute myeloid leukemia, i…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies [Phase 1]
A Phase 1 clinical trial update for a study of novel anti-leukemia agents used in Flu/Mel reduced-intensity conditioning transplant for myel…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: Study of the Relationship Between the Pharmacokinetics (PK) and Pharmacodynamics of Venetoclax in Patients With Acute Myeloblastic Leukemia [NA]
This clinical study investigates how the pharmacokinetics of venetoclax relate to its pharmacodynamics in patients with acute myeloid leukem…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: IFN-α in Relapse Prevention. [Phase 2]
Phase 2 clinical trial update evaluating interferon alpha for relapse prevention in acute myeloid leukemia and myelodysplastic syndromes; no…
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CLINICAL_TRIALS trial_result · 2026-03-03Clinical Trial Update: Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1]
Phase 1 study of pevonedistat in combination with belinostat for relapsed or refractory acute myeloid leukemia or myelodysplastic syndromes …
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: A Longitudinal Multi-Center Molecular Biomarker Discovery Registry for Patients With Hematologic Malignancies
A multi-center registry sponsored by Tempus AI aims to discover molecular biomarkers across hematologic malignancies, including acute myeloi…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML. [Phase 2]
A Phase 2 clinical trial evaluating venetoclax and azacitidine with homoharringtonine, followed by allogeneic hematopoietic stem cell transp…
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Phase 1 Study of AUTX-703 in Relapsed/Refractory AML and MDS [Phase 1]
Phase 1 study of AUTX-703 for relapsed or refractory acute myeloid leukemia and relapsed/refractory myelodysplastic syndromes is active but …
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: FHD-286 With Low-Dose Weekly Decitabine/Venetoclax in Patients With Acute Myeloid Leukemia [Phase 1]
Phase 1 study evaluating FHD-286 in combination with low-dose weekly decitabine and venetoclax in adults with acute myeloid leukemia or myel…