Acute Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: CART123 Cells With or Without Ruxolitinib in Relapsed/Refractory Acute Myeloid Leukemia [Phase 1]
Phase 1 trial evaluating CART123 CAR-T cells with or without the JAK2 inhibitor ruxolitinib in relapsed/refractory acute myeloid leukemia; t…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating combinations of ivosidenib and venetoclax with or without azacitidine in IDH1-mutated hematologic mali…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: GRanulocyte Augmented Cord Blood Transplantation for Poor Risk leukaEmia [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study of granulocyte-augmented cord blood transplantation for patients with poor-risk…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Azacitidine, Venetoclax, and Pevonedistat in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial is evaluating a three-drug combination of azacitidine, venetoclax, and pevonedistat in newly diagnosed acute myel…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant [Phase 2]
Phase 2 clinical trial evaluating CMV-MVA Triplex vaccination in HLA-matched related stem cell donors to prevent cytomegalovirus infection i…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Master Framework For Relapse or Refractory Acute Myeloid Leukemia
A clinical trial update describes a master framework for relapse or refractory acute myeloid leukemia and notes that the study is currently …
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment [Phase 1]
Phase 1 study evaluating the pharmacokinetics and safety of the oral decitabine and cedazuridine combination in cancer patients with renal i…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: A Study of ADCLEC.syn1 in People With Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating ADCLEC.syn1 in adults with acute myeloid leukemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome [Phase 2]
Phase 2 study of venetoclax in combination with decitabine for relapsed/refractory acute myeloid leukemia or relapsed high-risk myelodysplas…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Optimised CD33 (FL-33) CAR T Therapy for Refractory/Relapsed Acute Myeloid Leukaemia [Phase 1]
A Phase 1 clinical trial investigating an optimised CD33 CAR T cell therapy (FL-33) for refractory/relapsed acute myeloid leukemia; currentl…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment [Phase 1]
A phase 1 trial is evaluating the pharmacokinetics and safety of orally administered decitabine in combination with cedazuridine in cancer p…
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Ivosidenib as Post-HSCT Maintenance for AML [Phase 2]
Phase 2 trial assessing Ivosidenib as post-transplant maintenance in patients with IDH1-mutant acute myeloid leukemia; the study is currentl…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: Effectiveness and Safety of ONUREG (Oral Azacitidine) in Chinese Patients With Acute Myeloid Leukemia
This clinical trial update reports on the effectiveness and safety of ONUREG (oral azacitidine) in Chinese patients with acute myeloid leuke…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Phase 1B/2A Trial of NADUNOLIMAB in Combination With Azacitidine (With/Without Venetoclax) in Patients With Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML) [Phase 1, Phase 2]
A Phase 1b/2a clinical trial evaluating Nadunolimab in combination with azacitidine, with or without venetoclax, for myelodysplastic syndrom…
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CLINICAL_TRIALS research · 2026-03-09Clinical Trial Update: A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy [Phase 2]
A Phase 2 trial is evaluating the combination of tagraxofusp with venetoclax and azacitidine in adults with untreated CD123+ acute myeloid l…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Role of Adrenomedullin in Leukemic Endosteal/Vascular Niches [NA]
This clinical trial update examines the role of adrenomedullin in the leukemic endosteal and vascular niches in acute myeloid leukemia. The …
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders [NA]
This update reports the completed status of a trial assessing bone marrow and kidney transplant for patients with chronic kidney disease and…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting [Phase 2]
This clinical trial update describes a Phase 2 study of venetoclax plus azacitidine for acute myeloid leukemia in the post-transplant settin…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Selinexor With Combination With Induction/Consolidation Therapy in Acute Myeloid Leukemia Patients [Phase 2]
A Phase 2 trial evaluating selinexor in combination with induction/consolidation therapy for untreated adult acute myeloid leukemia; the stu…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: A Study of the Combination of Ivosidenib, Azacitidine, and Venetoclax Followed by Ivosidenib Alone in People With Acute Myeloid Leukemia [Phase 2]
A Phase 2 clinical trial at Memorial Sloan Kettering Cancer Center is evaluating a combination of Ivosidenib, Azacitidine, and Venetoclax fo…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Evaluation of Chemotherapy-induced Cognitive Disorders During the Treatment of Hematological Malignancies
A clinical trial update notes a study evaluating chemotherapy-induced cognitive disorders in patients treated for hematological malignancies…
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker [Phase 2]
This Phase 2 trial compares hypomethylating agents to intensive chemotherapy in Acute Myeloid Leukemia, using 5hmC as a blood-based minimal …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid Leukemia [Phase 1]
A Phase 1 clinical trial evaluating a CD33-targeted CAR T cell therapy for recurrent or refractory acute myeloid leukemia, currently recruit…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy
Clinical trial update from University Health Network, Toronto evaluating the risk of myelodysplastic syndrome and acute myeloid leukemia in …
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant [Phase 1]
Phase 1 clinical trial update evaluating maintenance therapy with tagraxofusp and azacitidine in CD123-positive acute myeloid leukemia and m…